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Introduction: Candida spp. has become increasingly resistant to antifungal
drugs, with elevated MIC levels causing a negative medical impact and
increasing the number of patients at risk of candidiasis. According to the
CDC, about 7% of Candida blood samples show reduced susceptibility
to fluconazole. Monitoring the antifungal resistance profile of Candida
spp. is vital, as non-Albicans species may limit treatment options.
Objective: Evaluate the antifungal effectiveness against clinical Candida
spp. isolates of six antifungals: amphotericin B, fluconazole, voriconazole,
itraconazole, caspofungin, and 5-fluorocytosine.
Methods: 100 samples were collected from various clinical samples at
the National Centre of Teaching Laboratories
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