isonicotinic acid hydrazide
Formazan
Schiff bases
molecular docking
antioxidant
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Objective: Synthesis, Characterization of formazan derivatives and studies the antioxidant activity
of prepared compounds and molecular docking. Methods: In this study, formazan compounds (III–XIV) were
produced by combining Schiff base compounds (I), (II) with diazonium salts resulting from reactions of different
aromatic amines with sodium nitrate in the presence of Con.HCl at 0–5°C. When isonicotinic acid hydrazide reacts
with (N,N-dimethylbenzaldehyde, 4-hydroxy-3-methoxybenzaldehyde) in the presence glacial acetic acid as a
solvent Schiff base compounds are created. Results: The prepared compounds were identified by FT-IR, 1H NMR,
13C NMR, then the antioxidant activity of the derivatives and molecular docking were studied. D
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