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DETERMINATION OF CEFALAXIN IN PHARMACEUTICAL PREPARATION BYMOLECULARY IMPRENTED POLYMER IN PVC MATRIX MEMBRANE: DETERMINATION OF CEFALAXIN IN PHARMACEUTICAL PREPARATION BYMOLECULARY IMPRENTED POLYMER IN PVC MATRIX MEMBRANE
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This current study was built on creating four electrodes based on molecularly imprinted polymers (MIPs). As the template using Cefalexin (CFX), 1-vinyl imidazole (VIZ) and vinyl acetate (VA) as monomer, and N, N-methylene bis acrylamide (MBAA) as cross-linkers and benzoyl peroxide as the initiator, two MIPs were prepared. The same composition was used in non-impressed polymers (NIPs) preparation, but without the template (Cefalexin). For the membranes preparation, numerous plasticizers, such as tri-oly phosphate (TOP) and di-octyl phthalate (DOP), were used in the PVC matrix, slop, detection limit, lifetime, and linearity range of CFX-MIPs electrodes are characteristics   studied.  To describe the created MIP, scanning electron microscopy (SEM) was used to study the properties of the electrodes, the slope, the detection limit, and the life time and linearity range. The effect of PH and interference on the efficiency of the electrode MIP was also investigated. The study has shown that the molecularly imprinted electrodes have high sensitivity and responsiveness to cefalaxin. The DPV value was linearly dependence on the aspirin concentration and a linear curve was obtained within the range of (1×10−1 - 5×10-4) M of cefalaxin with correlation coefficients are about (0.9941, 0.9899, 0.9936 and 0.9837) with slops value of (-18.48, -18.84, -18.60 and -19.47) and the detection limit for all electrodes ranging from (6×10-1-9×10-1) M.In the selectivity measurements results that we obtained there's no interaction with the cefalexin drug on interfering cations (K+, Ca+2, Al+3) and certain pharmaceutical additives such as methylparaben, propylparaben and trisodium citrate. The preparation electrodes have been shown good response including testing pharmaceutical analysis.The strategy employed is easy and fast. CFX membranes also have a short reaction speed, excellent mechanical stability, are removable and quick to create.

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Publication Date
Wed Oct 20 2021
Journal Name
Ibn Al- Haitham Journal For Pure And Applied Sciences
Polymer Chain Reaction (PCR): Principle and Applications
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The new, standard molecular biologic system for duplicating DNA enzymatically devoid of employing a living organism, like E. coli or yeast, represents polymerases chain reaction (PCR). This technology allows an exponential intensification of a minor quantity of DNA molecule several times. Analysis can be straightforward with more DNA available. A thermal heat cycler performs a polymerization chain reaction that involves repeated cycles of heating and cooling the reactant tubes at the desired temperature for each reaction step. A heated deck is positioned on the upper reaction tube to avoid evaporating the reaction mixture (normally volumes range from 15 to 100 l per tube), or an oil layer can be placed on a reaction mixture su

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Publication Date
Tue Sep 01 2009
Journal Name
Journal Of Economics And Administrative Sciences
Determine the optimal decision in the process of production planning usingDynamic programming style
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The operation of production planning is a difficult operation and it's required High effect and large time especially it is dynamic activity which it's basic variables change in continuous with the time, for this reason it needs using one of the operation research manner (Dynamic programming) which has a force in the decision making process in the planning and control on the production and its direct affect on the cost of production operation and control on the inventory.

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Publication Date
Mon Nov 01 2021
Journal Name
International Journal Of Nonlinear Analysis And Applications
Solution of Riccati matrix differential equation using new approach of variational ‎iteration method
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To obtain the approximate solution to Riccati matrix differential equations, a new variational iteration approach was ‎proposed, which is suggested to improve the accuracy and increase the convergence rate of the approximate solutons to the ‎exact solution. This technique was found to give very accurate results in a few number of iterations. In this paper, the ‎modified approaches were derived to give modified solutions of proposed and used and the convergence analysis to the exact ‎solution of the derived sequence of approximate solutions is also stated and proved. Two examples were also solved, which ‎shows the reliability and applicability of the proposed approach. ‎

Publication Date
Fri Mar 01 2019
Journal Name
Spatial Statistics
Efficient Bayesian modeling of large lattice data using spectral properties of Laplacian matrix
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Spatial data observed on a group of areal units is common in scientific applications. The usual hierarchical approach for modeling this kind of dataset is to introduce a spatial random effect with an autoregressive prior. However, the usual Markov chain Monte Carlo scheme for this hierarchical framework requires the spatial effects to be sampled from their full conditional posteriors one-by-one resulting in poor mixing. More importantly, it makes the model computationally inefficient for datasets with large number of units. In this article, we propose a Bayesian approach that uses the spectral structure of the adjacency to construct a low-rank expansion for modeling spatial dependence. We propose a pair of computationally efficient estimati

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Publication Date
Tue Feb 01 2022
Journal Name
Journal Of Engineering
Permanent Deformation Characterization of Stone Matrix Asphalt Reinforced by Different Types of Fibers
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This paper focused on the stone matrix asphalt (SMA) technology that was developed essentially to guard against rutting distress. For this procedure, fibers play a racy role in stabilizing and preventing the drain down problem caused by the necessity of high binder content coupled with their strengthening effect. A set of specimens with cylindrical and slab shapes were fabricated by inclusions jute, polyester, and carbon fibers. For each type, three contents of 0.25%, 0.5%, and 0.75% by weight of mixture were added by lengths of 5, 7.5, and 10 mm. The prepared mixtures were tested to gain the essential pertained parameters discriminated by the values of drain down, Marshall quotient, rut depth, and dynamic stability. It

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Publication Date
Fri Jan 01 2021
Journal Name
Journal Of Economics And Administrative Sciences
Predicting Social Security Fund compensation in Iraq using ARMAX Model
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Time series have gained great importance and have been applied in a manner in the economic, financial, health and social fields and used in the analysis through studying the changes and forecasting the future of the phenomenon. One of the most important models of the black box is the "ARMAX" model, which is a mixed model consisting of self-regression with moving averages with external inputs. It consists of several stages, namely determining the rank of the model and the process of estimating the parameters of the model and then the prediction process to know the amount of compensation granted to workers in the future in order to fulfil the future obligations of the Fund. , And using the regular least squares method and the frequ

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Publication Date
Fri May 29 2026
Journal Name
Analytical Methods In Environmental Chemistry Journal
A review of comparative analytical methods for β-lactam antibiotics and heavy metals in pharmaceutical products and human biological matrices
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A review of comparative analytical methods for β-lactam antibiotics and heavy metals in pharmaceutical products and human biological matrices

Publication Date
Sat Dec 30 2023
Journal Name
Iraqi Journal Of Pharmaceutical Sciences( P-issn 1683 - 3597 E-issn 2521 - 3512)
Preparation, In-vitro, and Ex-vivo Evaluation of Ondansetron Loaded Invasomes for Transdermal Delivery
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Invasomes are newly developed types of nanovesicles. A vesicular drug delivery system is considered one of the approaches for transdermal delivery to enhance permeation and improve drug bioavailability. Ondansetron is a serotonin receptor antagonist used for treating vomiting associated with different clinical cases. The study aimed to prepare invasomal dispersions for improving permeation of ondansetron across the skin with a controlled release pattern. Twenty-seven formulas of ondansetron-loaded invasomes were prepared by a modified mechanical dispersion method. These formulas were optimized by studying the effect of variables on entrapment efficiency. Vesicle size, polydispersity, zeta potential, in-vitro release and ex-vivo perm

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Publication Date
Thu Mar 30 2017
Journal Name
Iraqi Journal Of Pharmaceutical Sciences ( P-issn 1683 - 3597 E-issn 2521 - 3512)
Preparation and In Vitro Permeation of Chlopheniramine Maleate (CPM) from Gel through Rat Skin
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Chlopheniramine maleate ( CPM ) , is  one  of   the  H- receptor antagonist  ,  widely used  in allergic  diseases ,like skin rash  and  pruritis .CPM 3%w/w was successfully  loaded in  2%w/w  sodium alginate (SA)    as a gel    base ,  and  to be considered   as  a  selected  formula .It was found  that  the diffusion   of  CPM    through   the  skin  of  albino  rat   was     increased   as  the concentration  of  CPM  increased from 2 %w/w sodium alginate  ,  More

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Publication Date
Wed Oct 17 2018
Journal Name
Journal Of Economics And Administrative Sciences
comparison between the methods estimate nonparametric and semiparametric transfer function model in time series the Using simulation
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 The transfer function model the basic concepts in the time series. This model is used in the case of multivariate time series. As for the design of this model, it depends on the available data in the time series and other information in the series so when the representation of the transfer function model depends on the representation of the data In this research, the transfer function has been estimated using the style nonparametric represented in two method  local linear regression and cubic smoothing spline method The method of semi-parametric represented use semiparametric single index model, With four proposals, , That the goal of this research is comparing the capabilities of the above mentioned m

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