SYNTHESIS, CHARACTERIZATION, AND  STUDY THE BIOLOGICAL  ACTIVITY OF SOME SCHIFF'S BASES, AND 1,3 - OXAZEPINE COMPOUNDS DERIVED  FROM  SULFAMETHOXAZOLE  DRUG: SYNTHESIS, CHARACTERIZATION, AND  STUDY THE BIOLOGICAL  ACTIVITY OF SOME SCHIFF'S BASES, AND 1,3 - OXAZEPINE COMPOUNDS DERIVED  FROM  SULFAMETHOXAZOLE  DRUG

Enaam F. Mousa; Ibtisam K. Jassim

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Publication Date

Wed Jun 30 2021

Journal Name

Iraqi Journal Of Market Research And Consumer Protection

Volume

13

Issue Number

1

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SYNTHESIS, CHARACTERIZATION, AND STUDY THE BIOLOGICAL ACTIVITY OF SOME SCHIFF'S BASES, AND 1,3 - OXAZEPINE COMPOUNDS DERIVED FROM SULFAMETHOXAZOLE DRUG: SYNTHESIS, CHARACTERIZATION, AND STUDY THE BIOLOGICAL ACTIVITY OF SOME SCHIFF'S BASES, AND 1,3 - OXAZEPINE COMPOUNDS DERIVED FROM SULFAMETHOXAZOLE DRUG

Keywords: Sulfamethoxazole

Schiff base

1

3-Oxazepine

antibacterial activity .

Enaam F. Mousa

Ibtisam K. Jassim

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This study including synthesis of some new Schiff bases compounds [1‐6] from the reaction of Sulfamethoxazole drug with some aromatic aldehydes in classical Schiff base method then treatment Schiff bases with succinic anhydride to get oxazepines rings [7-11]These derivatives were characterized by melting point, FT‐IR, ¹H NMR and mass spectra. Some of synthesized compounds were evaluated in vitro for their antibacterial activities against three kinds of pathogenic strains Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa by agar diffusion disk method, and against the fungal species (Candida). The results showed that some of these derivatives have good antibacterial activities compared to biological activity of parent drug.

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Publication Date

Tue Oct 21 2025

Journal Name

American Journal Of Research In Humanities And Social Sciences

Jurisdiction In Outer Space From The Perspective Of International Law

Outer space

Criminal jurisdiction

space law

International Space Station.

Mohammed

Ahmed Amer

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This research aims to clarify the principles governing the exploration and utilization of outer space, emphasizing the role of international law, particularly international criminal law, in addressing crimes committed beyond Earth whether aboard spacecraft, the International Space Station, or in outer space generally. It examines relevant international treaties governing outer space activities, evaluates their strengths and ambiguities, and highlights deficiencies in their provisions. Furthermore, the study analyzes traditional principles of state criminal jurisdiction territoriality, nationality, universality, and protection and assesses their applicability to offenses committed in outer space.

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Publication Date

Wed Oct 02 2013

Journal Name

Journal Of Biology, Agriculture And Healthcare

The Prevalence of Aerobic Bacteria Isolated from Horses Fecal Samples

Aseel

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Dietary components and changes cause shifts in the gastrointestinal microbial ecology that can play a role in animal health and a wide range of diseases. However, most information about the microbial populations in the gut of horses has not been quantitative. The objective of this study was to characterize the fecal bacterial and its prevalence in healthy horses and diarrheal one in a period from September 2010 to July 2013. Out of 100 Fecal samples of horses (from farms in Al-furusyia club) in Baghdad were examined for microbial differentiation founded eighty percent of the fecal samples isolated from healthy horses. The most common pathogen found were Streptococcus spp. (33.7%), Escherichia coli (20.9%), , and Staphylococcus aureus (9.2

Publication Date

Tue Jan 09 2024

Journal Name

مجلة واسط للعلوم الریاضیة

The development of judo from a historical perspective (1880-1980)

development of sports

martial arts

judo

sports history.

زينب

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Judo has witnessed tremendous developments since its inception until the present day. It has been distinguished by its adaptation to the various challenges it has faced throughout the ages. Judo is one of the sports that have been affected by social, technological and cultural changes. These changes reflect its transformation from the traditional Japanese martial art to a global sport practiced. All over the world, therefore, studying the historical development of judo is important, as it provides valuable insights into the development of martial arts over a century, by studying the origins, principles and techniques of judo for the period (1880 - 1980), and also enables us to gain an understanding A deeper understanding of how the art form

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Publication Date

Mon Feb 16 2026

Journal Name

Journal Of Studies And Researches Of Sport Education

The effect of using the educational bag on the level of learning some offensive skills with the epee weapon

The effect of using the educational bag on the level of learning some offensive skills with the epee weaponDr. Lamia Hassan Al-Diwan

D. Fatima Abdel-Maliki

Dr. Kholoud Laith Abdel Karim2005 Technical and technological development has been increasing day after day and has included all areas of life

including the educational process

which has benefited from technologies such as (computer

video

and pictorial models) in introducing them as tools to aid the learning process. Educational packages have proven their effectiveness in education as they prepare learners with different areas of experience. Sensory audio-visual

through which the learner acquires different educational experiences through interaction

practice

participation

and communication with the data of the surrounding environment through the diversity of knowledge sources that suit his inclinations and needs. The research aimed to prepare an educational bag to teach some offensive skills in the epee weapon. And to find out the effect of using the proposed educational bag on the level of learning some offensive skills in the epee weapon. We hypothesized that the proposed educational package has a positive impact on the level of learning some offensive skills with the epee weapon. There were statistically significant differences in testing the level of learning some offensive skills with the epee weapon between the post-tests of the experimental and control groups

and in favor of the experimental group. The researchers used the experimental method to suit the nature of solving the research problem

and the research sample was chosen intentionally from the girls’ fencing club players (beginners) in the governorate. Basra for the year 2005. The number of players was (16)

which represented the entire study population. The experiment was conducted in the sports hall of the South Oil Sports Club in Basra. We concluded that the educational package has a positive impact on the level of learning some offensive skills in the epee weapon. There were statistically significant differences in the learning level test for some offensive skills in the epee weapon between the experimental group and the control group in the post-tests and in favor of the experimental group. We recommended the necessity of using the proposed educational curriculum to learn some offensive skills in the epee weapon in fencing lessons or in sports clubs. Adopting modern techniques in training

teaching or teaching fencing skills and searching for new methods. Conducting similar studies on other skills or different samples.Keywords: educational bag

offensive skills with an epee weapon

fencing game. Teaching methods. Basra Girl Sports ClubLamya Hassan Aldewan [email protected] of Basra - College of Education and Sports Scienceshttps://orcid.org/0000-0003-0377-6915 Keywords educational bag

offensive skills with an epee weapon

fencing game. Teaching methods. Basra Girl Sports Club

‏Lamyaa

Fatima

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Publication Date

Sun Dec 07 2014

Journal Name

Baghdad Science Journal

Synthesis of N –sulfamethoxazolederivative imide on polymeric chain

Sulfamethoxzole drug

poly acryloyl chloride

polyamides derivatives.

Sameaa J. Khammas

Amal S.

Tamador A.

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The present work involved synthesis of several new N-Sulfamethoxazol derivatives imide on Polymeric chain by two steps. The first stip involved preparation of N- (sub.orunsub benzoyl and sub unsub acetyl) amidyl sub sulfamethoxazole (1-5) by condensation of sulfamethoxazole drug with many substituted acid chloride, then the second step include, preparation new five N-(acrly-N–sub or unsub benzoyl) imidyl substituted sulfamethoxazol(6-10) by reaction of poly acryloyl chloride with the prepared compound (1-5) in first stepin asuitable solvent in the presenceamount triethylamine (Et3N) with heating. The structure confirmations of all polymers wereconfirmed using FT-IR,1H-NMR,13C-NMR and UV spectroscopy. Other physical properties including so

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Publication Date

Sun Jun 07 2009

Journal Name

Baghdad Science Journal

Synthesis of Fibrous Hydroxyapatite through Sol-Gel Route

"Bioceramic

hydroxyapatite

sol-gel

biocompatibility

agar"

Abdulsalam K.

Maria.

Thair

Hameed

Murtda A

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The sol-gel route using an agar gel with calcium nitrate and phosphate solution as starting materials for producing hydroxyapatite (HAP). The product formed were needle like, zigzag and straight fibres. The fibrous products on sintering transformed into stoichiometric HAP with a biological Ca/P ratio of 1.67. The influences of pH, temperature, nature of base and phosphate solution on the growth of fibrous HAP were studied. The pH of the solution was found to greatly influence the growth rate and morphology of the resultant product. The optimum gel temperature was found to be 60oC and sintering temperature of 900oC for 1 hour. The crystalline, thermal, functional and morphological characteristics of the fibrous HAP were investigated.

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Publication Date

Mon Jul 01 2019

Journal Name

J. Pharm. Sci. & Res.

Synthesis of coumarin by Pechman reaction - A Review

Coumarin

Pechman reaction

phenols

β-keto esters

Kawther

Nebeas

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Phenol condensed with β-keto esters via Pechmann condensation to form derivatives of Coumarin in various reaction conditions by two ways. Present paper is comparative study of synthesis Coumarin with the yield of product , reaction time and reaction conditions.

Publication Date

Fri Jul 05 2013

Journal Name

Pharmacie Globale International Journal Of Comprehensive Pharmacy

SYNTHESIS OF NEW PROPRANOLOL DERIVATIVES AS POSSIBLE PRODRUGS

propranolol

prodrugs

bioavailability

first- pass metabolism

Mohammed H

May Mohammed Jawad

Amera Abbas

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Propranolol is a nonselective-adrenergic blocker used in the treatment of hypertension, cardiac arrhythmias, and angina pectoris. A significant problem in propranolol therapy is that it undergoes extensive presystemic metabolism after oral administration leading to reduced bioavailability. In this study, two new propranolol derivatives have been designed, synthesized and characterized. These compounds were formed by acylation of propranolol followed by nucleophilic substitution reaction of acylated propranolol, these derivatives were analyzed for IR, CHN, melting points, and evaluated for their lipophilic properties compared with propranolol. The lower partition coefficient of these two derivatives revealed that the prodrug approach may be

Publication Date

Thu Jan 01 2015

Journal Name

International Journal Of Engineering And Applied Sciences

SYNTHESIS OF CIPROFLOXACIN LACTATE PROCAINAMIDE AS MUTUAL PRODRUG

Taghreed

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In this research, two drugs were bonded through amide and ester attachment, using lactic acid as aspacer binder, produced di pro drug such as Procain and Ciprofloxacin. Since Procain has ailocail anesthetic action and Ciprofloxacin as antibacterial drug was reacted with lactic acid produced ester compound (1), then the carboxylic acid of lactic acid could reacted with free Procain oil produced amide attachment, the controlled drug release in different pH values at 37C˚was studied to improve their characteristic and to minimize the side effect of the drug could be used in broad spectrum activity as atherapeutic material.This mutual prodrug was used with another biological active drug instead of single action. The prepared prodrug was charac

Publication Date

Wed Jun 29 2022

Journal Name

Periodicals Of Engineering And Natural Sciences (pen)

The impact of the internet of things on information institutions from the perspective of library employees

Abdul Rahman M.

Suaad H. Hassan

Huda Abbas

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