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Role of Diffusion-Weighted MR Imaging in Characterization of Posterior Fossa Tumors

Background: Conventional  MR imaging is essential for diagnosis and evaluation of the posterior fossa tumors  Objectives: To assess the value of diffusion weighted imaging and apparent diffusion coefficient in making distinction between different histological types of posterior fossa tumors.

Type of the study: Cross-sectional study.

Methods: Brain MRI and DWI assessed 19 patients (12 female and 7 male) with MRI diagnosis of posterior fossa tumors. absolute ADC values of contrast -enhancing solid tumor region and ADC ratio of solid tumor to ADC of normal -appearing deep White matter were compared with histological diagnosis postoperatively .The mean ADC value and ratio were determined by using a 2-tailed T test. Results: In eight of  medulloblastoma ,The mean  ADC value was 0.67±0.14x 10-3 mm 2/s  and  ratio 0.86±0.19  ,   ependymoma (n=3), ADC value 1.09 ±0.14 x10 -3 mm 2 /s and ratio 1,43±0.13   ,  pilocytic astrocytoma (n=4) ADC value 1,72 ±0.27x10 -3 mm2/s and ratio 2.19±0.4, brainstem glioma (n=2) with ADC value1.18±0.06 x10-3mm2/s and ratio 1.64±0.08 , haemangioblastoma  (n=1) with ADC value1.46x10-1mm2/s and ratio 1.87 , and meningioma with ADC value 0.72x10-3mm2/s and ratio 0.85. ADC values were higher in JPA than in ependymomas and medulloblastoma (P value <o,o5).ADC ratio were also  statistically significant difference among these three tumors type .

Conclusion: calculation of apparent diffusion coefficient value in the solid enhancing portion of tumor   seems to be reliable for  differentiate between  medulloblastoma at one end and , juvenile pilocytic astrocytoma (JPA) and ependymoma at other end as the former has ADC of < 1 while other tumors have ADC value of >1.

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Publication Date
Thu Jun 30 2022
Journal Name
Iraqi Journal Of Science
Brain MR Images Classification for Alzheimer’s Disease

    Alzheimer’s Disease (AD) is the most prevailing type of dementia. The prevalence of AD is estimated to be around 5% after 65 years old and is staggering 30% for more than 85 years old in developed countries. AD destroys brain cells causing people to lose their memory, mental functions and ability to continue daily activities. The findings of this study are likely to aid specialists in their decision-making process by using patients’ Magnetic Resonance Imaging (MRI) to distinguish patients with AD from Normal Control (NC). Performance evolution was applied to 346 Magnetic Resonance images from the Alzheimer's Neuroimaging Initiative (ADNI) collection. The Deep Belief Network (DBN) classifier was used to fulfill classification f

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Publication Date
Fri Nov 01 2013
Journal Name
East Asian Journal On Applied Mathematics
Free Boundary Determination in Nonlinear Diffusion
Abstract<p>Free boundary problems with nonlinear diffusion occur in various applications, such as solidification over a mould with dissimilar nonlinear thermal properties and saturated or unsaturated absorption in the soil beneath a pond. In this article, we consider a novel inverse problem where a free boundary is determined from the mass/energy specification in a well-posed one-dimensional nonlinear diffusion problem, and a stability estimate is established. The problem is recast as a nonlinear least-squares minimisation problem, which is solved numerically using the <italic>lsqnonlin</italic> routine from the MATLAB toolbox. Accurate and stable numerical solutions are achieved. For noisy data, inst</p> ... Show More
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Publication Date
Tue Apr 30 2024
Journal Name
International Journal On Technical And Physical Problems Of Engineering
Deep Learning Techniques For Skull Stripping of Brain MR Images

Deep Learning Techniques For Skull Stripping of Brain MR Images

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Publication Date
Wed Apr 02 2014
Journal Name
Journal Of Theoretical And Applied Information Technology
TUMOR BRAIN DETECTION THROUGH MR IMAGES: A REVIEW OF LITERATURE

Today’s modern medical imaging research faces the challenge of detecting brain tumor through Magnetic Resonance Images (MRI). Normally, to produce images of soft tissue of human body, MRI images are used by experts. It is used for analysis of human organs to replace surgery. For brain tumor detection, image segmentation is required. For this purpose, the brain is partitioned into two distinct regions. This is considered to be one of the most important but difficult part of the process of detecting brain tumor. Hence, it is highly necessary that segmentation of the MRI images must be done accurately before asking the computer to do the exact diagnosis. Earlier, a variety of algorithms were developed for segmentation of MRI images by usin

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Publication Date
Mon Jan 02 2006
Journal Name
Journal Of The Faculty Of Medicine Baghdad
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Publication Date
Sun Feb 03 2019
Journal Name
Journal Of The College Of Education For Women
New vision of Mr. Abdul Mahdi Al-Muttafiqi in the light of unpublished documents

New vision of Mr. Abdul Mahdi Al-Muttafiqi in the light of unpublished documents

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Publication Date
Mon Nov 29 2021
Journal Name
Iraqi Journal Of Science
Detection of Pan Braf in Thyroid Tumors in Iraqi Patients

The B-type Raf kinase (BRAF) is a member of RAS\RAF\MEK\ERK pathway and this pathway can lead to increased cellular growth, invasion and metastasis. The mutated BRAF protein activates MAPK signaling pathway, results in abnormal cellular growth, apoptosis resistance, tumor progression and metastasis. Pan-BRAF is one of available BRAF monoclonal antibodies and shared by both the wild and mutant BRAF.BRAF status is mostly determined by DNA sequencing methods. In this investigation we assessed the monoclonal Pan BRAF specific antibody that can identify wild and mutant type proteins together in formalin-fixed paraffin-embedded thyroid tumor tissues by Immunohistochemistry (IHC). Archival thyroid samples from 43 iraqi patients were immunohisto

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Publication Date
Mon Jan 30 2023
Journal Name
Iraqi Journal Of Science
Generalized Jacobian Weighted Modulus of Smoothness

      The topic of modulus of smoothness still gets the interest of many researchers due to its applicable usage in different fields, especially for function approximation. In this paper, we define a new modulus of smoothness of weighted type. The properties of our modulus are studied. These properties can be easily used in different fields, in particular, the functions in the  Besov spaces   when

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Publication Date
Mon Apr 20 2020
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
Some Aspects of Weighted Rayleigh Distribution

In this paper, we proposed a new class of weighted Rayleigh distribution based on two parameters, scale and shape parameters which are introduced in Rayleigh distribution. The main properties of this class are investigated and derived.

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Publication Date
Mon Nov 01 2010
Journal Name
Al-nahrain Journal Of Science