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Toll like receptor 2(TLR2) in acne vulgaris patients before and after oral isotretinion therapy
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Background: Acne vulgaris is one of the top three most commonly encountered dermatological problems worldwide in both primary and secondary care. Human keratinocytes express functional TLR2 heterodimers. An increased expression of TLR2 was detected in the epidermis of inflammatory acne lesions, as observed in normal skin; the expression level increased with the degree of differentiation of the keratinocytes. TLR2 expression is upregulated in inflammatory acne lesions and induced by C. acnes. The current study conducted to assess the oral isotretinion treatment effect on the acne vulgaris patients by  evaluated the Toll Like Receptor 2 as a major  immune system marker in Acne vulgaris immune response.

 Methods: 50 patients with acne vulgaris seen in  outpatient clinic of dermatology centre(Al-Baidhaa out clinic center) in Baghdad during the period 1/9/2017 to 1/8/2018. The  diagnosis of patients were done by the specialist dermatologist only sever and moderate acne cases were chosen. Fifty serum  samples were collected before oral isotretinion therapy, only forty-five serum samples were collected after 8 weeks of oral isotretinion therapy. All patients have received 0.5mg-1mg/kg/day of oral isotretinoin. The mean ages was 22 years(range, 16-36 years). A total of 50 patients, 36(72%) of patients were females and 14(28%) were males. Furthermore 43(86%) of cases have heredity history. Also control serum samples were collected from people without acne and they chose with the same mean ages. The serum samples were stored at -70°C for up to six months. ELISA test for quantitative determination of TLR2 human was done. Statistical analysis was done using T-test.

Results: Highly significant statistical difference were noticed (p<0.001) when we compare study group after therapy with control group, also highly significant statistical difference was noticed (p<0.01) when we compare study group before therapy with control group.

Conclusion: Significant decrease of TLR-2 level was noticed in study group after isotretinoin therapy in comparison with same group before therapy and also with the control group. Pronouncedly the effects of oral isotretinion suggest a path towards importance of this therapy as an anti-acne agent

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Publication Date
Tue Dec 22 2020
Journal Name
Journal Of Accounting And Financial Studies ( Jafs )
The effect of insider trading in accounting information on the investors decisions: An Applied Study In a sample of corporation listed in Iraq Securities Exchange
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This research aims to discuss an important issue because of its role in increasing the efficiency of financial markets and boost investor confidence by a insider trading, which arises as a result of leaking secret information to some investors and reliable in the process of trading shares in the Iraq Stock Exchange And thus obtain abnormal profits at the expense of other investors. Research was based on the assumption that " Where shortcomings in local regulations relating to disclosure and insider trading in accounting information leads to the activate the phenomenon of insider trading in accounting information in the Iraq Stock Exchange and including a negative impact on investors' decisions ". and Because of the difficulty the discove

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Publication Date
Wed Oct 17 2018
Journal Name
Journal Of Economics And Administrative Sciences
Implications of Financial Reporting Governance in rationalizing investors decisions In financial markets in light of An International Financial Reporting Standards (IFRS)/ An analytical study of a selected sample of the joint stock companies in Iraq
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The financial crises that occurred in South East Asia and America, and the discovery of the financial and administrative corruption that affected these companies, which led to the crisis. Since then, organizations and institutions interested in accounting have begun new ways to further rationalize the management of these companies. Hence the concept of governance, which means good governance. Al-Susiya confirmed its adoption of the financial reporting standards and adopted internal and external auditing for the purpose of increasing the reliability and credibility of the financial and reports that increase the confidence of investors in making their investment decisions in the financial markets The study dealt with the contributi

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Publication Date
Wed Jun 21 2017
Journal Name
Research Journal Of Pharmaceutical, Biological And Chemical Sciences
Synthesis and characterization of Mixed-Ligand Complexes of Oxalic Acid and Trimethoprim with Mn(II), Co(II), Ni(II), Cu(II),Zn(II), and Cr (III) Ions: and antimicrobial Activities
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Publication Date
Sat Feb 02 2019
Journal Name
Journal Of The College Of Education For Women
The Gender and Society
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Publication Date
Sun Jan 01 2023
Journal Name
Heart Transplantation
Cardioimmunology and Heart Transplantation
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Publication Date
Fri Jan 01 2021
Journal Name
Beirut: Kanz Publising House
Rumi and the Qura’n
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Publication Date
Mon Jun 01 2020
Journal Name
Journal Of Planner And Development
Senses and urban Landscape
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The city is often discussed in barren, eviscerated terms and in technical jargon by urban professionals as if it were a lifeless, detached being. In fact, it is a sensory, emotional, lived experience. How often do strategic urban plans start with the words ‘beauty’, ‘love’, ‘happiness’ or ‘excitement’, as opposed to ‘bypass’, ‘spatial outcome’ or ‘planning framework, So the research problem was formed by the weakness of the sensory perception of cities and the weakness of the sense of different spaces, which in turn leads to weakness of belonging, identity and clarity, Therefor we focus here on the sensory perception. The hypothesis Recognize Senses as helpful tool in increasing people's understanding of differe

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Publication Date
Wed May 24 2023
Journal Name
College Of Islamic Sciences
Rwandan branches and objectives
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This is a search for Al-Rwandiyah and its heretical deviant sects, and its destructive goals that targeted the Arab nation, and its true Islamic religion in order to exhale poisons of demolition and sabotage, leading to its racist, populist goals ( ) that the Magi aspire to to restore the so-called ancient Persian glories, and undermine the Abbasid caliphate.
Al-Biruni said: (And that a person will emerge who will restore the Magian state and seize all the land, and remove the king of the Arabs) (), and among the indications of Ibn Al-Nadim is that a populist man called Muhammad bin Al-Hussein who was turned into Zaidan () was (claiming... the transition of the Islamic state to a state Persia ..... and their religion, which is the rel

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Publication Date
Wed Feb 25 2026
Journal Name
Al–bahith Al–a'alami
Television and Agenda Building
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Most media studies on the development of the agenda have focused on the relationship between the content of the media and the audience of these media, and the extent of its impact on the agenda of the media, in addition to comparing it to the extent of interest in the agenda of those means. While in the construction of the agenda, we focus on the relationship between news sources and the media and the role of these sources in the process Building the agenda.These sources are institutions, parties, pressure groups, interest groups, the head of state and other media. The impact of these sources on the process of building the agenda are shown through the process of the selection of resources by the channel and communicators, and the technic

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Publication Date
Tue Jun 01 2010
Journal Name
Journal Of The College Of Languages (jcl)
Racism and blacks struggle
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    Traditionally, women playwrights in general, and black women playwrights in particular have been excluded from the American theater       because of racial and gender oppression. However, early twentieth-century African-American women playwrights, such as Angelina Weld Grimke (1880-1958), Alice Dunbar-Nelson (1875-1935), Marry Burrill (1879-1946), and Myrtle Smith Livingston (1901-1973), whose works have been overshadowed for decades, were able to express their awareness of the racial discrimination facing African-Americans. They also paved the way for the next generation of black women playwrights, such as Alice Childress (1920-1994), Lorraine Hansberry (1930-1965) and many others.

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