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Comparison between Reference Infliximab (Remicade) and its Biosimilar (Remsima) in Patients with Ankylosing Spondylitis: A Field-based Pharmacoeconomic Study
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Background: Ankylosing spondylitis is a chronic inflammatory disease that mostly involves the spine and sacroiliac joints. It is associated with a decreased quality of life. Biological medicines such as infliximab and its biosimilar are the mainstay treatments for active ankylosing spondylitis.

Objective: The study objective was to conduct a pharmacoeconomic study comparing the cost-effectiveness of the reference infliximab with its biosimilar in ankylosing spondylitis patients visiting public hospitals.

Subjects and Method: This is a two-center pharmacoeconomic study performed at two large teaching governmental hospitals in Baghdad, Iraq, which supplied infliximab to outpatients with ankylosing spondylitis. The outcome data were obtained from patient’s medical records and face-to-face interviews with the patients from December 2021 through April 2022. The Independent T-Test was used to measure the differences in areas of utility, and quality of life, between the two infliximab groups.

Results: The study recruited 62 patients with ankylosing spondylitis who received infliximab (31 received Remicade, and 31 received Remsima) for at least 12 weeks at two public teaching hospitals. The mean age of the patients was 37.85 years and 83.9% were men. In general, both reference infliximab and its biosimilar were successful in increasing the quality of life. Their importation costs were different from 2019 to 2021. The incremental cost-effectiveness ratio of reference infliximab versus biosimilar was $ 40,909/quality-adjusted life year (QALY) according to 2019 pricing. In contrast, in 2021 reference infliximab (Remicade) was less expensive and yielded slightly better quality of life improvement than biosimilar (Remsima) making Remicade more cost-effective (dominant).

Conclusion: Remicade was slightly superior to Remsima in quality of life improvement. However, it was difficult to determine whether the reference or its biosimilar was more cost-effective in 2019 because the health officials did not specify a willingness to pay per quality-adjusted life year. Compared to Remsima, Remicade was more cost-effective in 2021 because it was less expensive and more effective in terms of quality of life improvement.

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Publication Date
Thu Feb 28 2019
Journal Name
Iraqi Journal Of Science
Evaluation of Petrophysical Characteristics of Carbonate Mishrif Reservoir in Ahdeb oil Field, Central Iraq
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Ahdeb oil field is located in the central block of Mesopotamia plain in Iraq. It has three domes AD-1,   AD-2, and AD-4.The current study represents characterization of carbonate Mishrif reservoir (Cenomanian-Early Turonian) in three wells (AD-A,AD-B,AD-C) at southern dome of Ahdeb oil field. Petrophysical properties were calculated using available well logs data such as neutron, density, sonic, gamma ray, resistivity and self-potential logs. These logs are digitized and then environmental corrections and interpretations were carried out using Techlog software. Petrophysical parameters such as shale volume, porosity, water saturation, hydrocarbon saturation, bulk water volume, etc. were determined and interpreted and illustrate

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Publication Date
Wed Mar 27 2019
Journal Name
Iraqi Journal Of Science
Petrophysical characterizations of Mishrif Formation in Selected Wells of Tuba Oil Field, Southern Iraq
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The current study includes building (CPI) & Petrophysical Evaluation of the Mishrif Formation (Cenomanian-Early Turonian) in Tuba oilfield, southern Iraq by using Interactive Petrophysics Program v3.5 (IP)  to evaluate different logs parameters that control the reservoir quality of Mishrif Formation such as shale volume, effective porosity, and water saturation. Mishrif Formation is subdivided into several units, which are characterized by different reservoir properties. These units are Top of Mishrif, MA, CR2, MB1, and MB2.The results of computer processed interpretation (CPI) show that the major  reservoir unit are (MB1 and MB2), which are characterized by high effective porosity and oil saturation. In addition, these uni

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Publication Date
Thu Oct 04 2018
Journal Name
Iraqi Journal Of Science
Geological modeling using Petrel Software for Mishrif Formation in Noor Oil Field, Southeastern Iraq
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Petrel is regards one of the most important software to delineate subsurface Petrophysical properties to the reservoir. In this study, 3D Integrated geological models has been built by using Petrel software. The process includes integrated Petrophysical properties and environmental approaches.
Noor oil field within Mishrif Formation in terms of structural geology represents asymmetrical anticlinal fold with direction NW-SE. Porosity and water saturation model have been built. The reservoir was divided into several reservoirs and Nonreservoir units depends on the Petrophysical properties for each zone. In addition,
intact model for the reservoir in terms of porosity and water saturation have been b

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Publication Date
Sat Dec 01 2018
Journal Name
Journal Of Economics And Administrative Sciences
The Role of Personality Characteristics of the Leader in Business Organizations Entrepreneurship (Field Research)
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This research is aiming to find the effective role of the personality characteristics of the Leader in business organization entrepreneurship by studying the effect of the special dimensions of personality characteristics (neuroticism, extraversion, openness, Agreeableness, and conscientiousness) on business organizations entrepreneurship dimensions representing in the two main dimensions (entrepreneurship direction and strategic entrepreneurship) across field study was conducted in thirteen private colleges in Baghdad.

The problem of the research relies in asking the question, is there an effect for Leader personality characteristics on business organizations entrepreneurship. and statistical methods hav

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Publication Date
Thu Feb 01 2024
Journal Name
Journal Of Engineering
The Economic Evaluation of Various Production Scenarios for Zubair Reservoir in the Kifl Field
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This work evaluates the economic feasibility of various production scenarios for the Zubair reservoir in the Kifl oil field using cash flow and net present value (NPV) calculations. The Kifl field is an exploratory field that has not yet been developed or assessed economically. The first well was drilled in 1960, and three other wells were later drilled to assess the oil accumulation, so in this research, Different production scenarios were evaluated economically. These scenarios were proposed based on the reservoir model of the Zubair formation in the field. The research methodology used QUE$TOR software to estimate capital expenditures (CapEx) and operating expenditures (OpEx) based on field-level data, production prof

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Publication Date
Wed Sep 08 2021
Journal Name
Journal Of Accounting And Financial Studies ( Jafs )
Strategic tax planning and its impact on reducing tax evasion
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Taxes are an essential axis in the economy as the most effective and effective economic tool in any country (economy). Expanding the scope of taxation without adequate study has produced a dangerous result with a negative impact that is almost apparent, namely (tax evasion), which stands as a barrier preventing the state from reaching Therefore, the research sought to study strategic tax planning and its importance in reducing tax evasion, and the research aims from that to prove the importance of adopting strategic planning in the field of taxes according to modern and effective scientific foundations to reduce tax evasion to enhance the achievement of tax evasion. The financing objective is in addition to the other objectives,

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Publication Date
Sat Oct 01 2016
Journal Name
2016 6th International Conference On Information Communication And Management (icicm)
Enhancing case-based reasoning retrieval using classification based on associations
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Publication Date
Fri Sep 15 2023
Journal Name
Al-academy
Focus groups strategy and its impact on the achievement of primary school students in art education
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Art education is one among the fundamental subjects for elementary school students, because it contributes to assembling learners’ personalities and developing their technical skills. For this reason, this research comes, which aims to understand the effect of the task groups’ strategy in developing the performance of elementary school students in art education. to realize the goal of the research, the researcher put the subsequent hypotheses:
-There is not any statistically significant difference at the amount (5%) between the typical many students between the experimental group that studied consistent with the strategy of task groups and therefore the control group that studied in keeping with the same old method that they obt

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Publication Date
Sun Jan 01 2023
Journal Name
Iraqi Journal Of Applied Physics
Effects of Magnetic Field on Growth and Electrical Characteristics of Tornado Gliding Arc Discharge
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This study investigates the characterization and growth dynamics of a Magnetically Stabilized Gliding Arc Discharge (MSGAD) system, generating non-thermal plasma with argon gas under atmospheric pressure and flow rates of 1-5 L/min. The electrical properties and growth patterns concerning gas flow rates and applied voltages were examined utilizing a magnetic field for stability. Using a digital oscilloscope, a correlation between voltage reduction and increased current was uncovered. An algorithm analyzes digital images to compute arc length, area, and volume. Results reveal how gas flow rate and applied voltage directly impact arc growth. Furthermore, the magnetic field's role in guiding and stabilizing the plasma discharge was explored. T

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Publication Date
Thu Jul 01 2021
Journal Name
Diyala Journal For Pure Science
Survey of Air Quality and Health Risk Assessment Around East Baghdad Oil Field, Iraq
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Air pollution evaluation of the operational processes in the East Baghdad oil field was carried out. The analysis was carried out by ICP-MS technique. Total Suspended Particles (TSP) air load was higher than Iraqi Standards and world international allowable limits of World Health Organization. The mean concentrations of gases carbon monoxide, carbon dioxide, sulfur dioxide, in the air were within national and world standards, while the mean concentration of nitrogen dioxide was higher than standard limits. The air of the study area is considered a good quality for CO, CO2 and NO2 with no health effect, while it is hazardous for TSP that have serious risk for people with respiratory disease. The mean concentrations of Cd, Cr, Cu and

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