Background:Oriental sore occurs mostly in the
mediteranian region , North Africa ,and the Middle East .
Rodents are the main reservoir for the parasite . The wet
type caused by L. major is rural and the dry type caused by
L. tropica is urban and humans are presumably the only
reservoir. Sand fly vectors are involved in all forms.
Objectives: This study aimed to show the most
important bacterial infections concomitant with cutaneous
leishmaniasis .
Methods; The study was performed on 75 patients (ages
1-50 years ) from both sexes were attending Skin Diseases
Department of Ramadi General Hospital during the period
extended from January to June 2000. These patients were
clinically diagnosed as patients with cutaneous
leishmaniasis. Skin specimens were taken for
bacteriological and parasitological investigations .The same
thing was done for specimens from 25 intact individuals
resembling the test group as negative controls.
Results: Children showed more lesions with Positive
cutaneous leishmaniasis, adult females, showed more l
lesions than adult males. Children showed more bacterial
isolates than adults, from both positive and negative l
lesions. Staphylococcal and Streptococcal isolates took the
first rank of isolation in all age groups and both sexes. E.
coli and fecal Streptococci were isolated from children
only.
Conclusion: Bacterial invasion for the skin lesion with
cutaneous leishmaniasis complicates the lesion and leads to
misdiagnosis, in addition to the delay of healing of the
lesion via bacterial end-products. There is a need for
accurate diagnostic techniques like polymerase chain
reaction (PCR) for both bacterial and parasitic agents,
suitable effective antimicrobial therapy, in addition to the
antileishmanial agents. Good sanitation of the lesion and
community education to prevent infections
Human cutaneous leishmaniasis (CL) is caused by Leishmania sp. parasite and endemic in Iraq. The current study was including analysis of available database from Iraqi CDC to determine the distribution of CL cases for the period (2008-2015 years) in Iraq. Total reported cases for this period were 17001 (range 2.9-10.5 per 100,000 individuals). Highest reported cases were recorded in the year 2015 (4000 cases). Male infections cases of CL (50.8%) were more than female infections (49.2%). Highest infections of CL were observed in the age group (5-14yr.) as (34.6%), While the lowest infection of CL were observed in the age group (>1yr.) as (4.3%). Highest infection case of CL was observed in the middle and west of Iraq (53%). In contrast,
... Show MoreLeishmaniasis is a group of parasitic diseases caused by Leishmania spp., an endemic infectious agent in developing countries, including Iraq. Diagnosis of cutaneous lesion by stained smears, serology or histopathology are inaccurate and unable to detect the species of Leishmania. Here, two molecular typing methods were examined to identify the promastigotes of suspected cutaneous leishmaniasis samples, on a species level. The first was species-specific B6-PCR and the second was ITS1-PCR followed by restriction fragment length polymorphism (RFLP) using restriction enzyme HaeIII. DNA was extracted from in vitro promastigote culture followed by amplification of kDNA by B6 or amplification and digestion of LITSR/L
... Show MoreAbstractBackgroundLeishmaniasis is endemic in Iraq, where both cutaneous and visceral forms of the disease are reported.ObjectivesTo determine the prevalence of cutaneous leishmaniasis (CL) and to identify associations of CL with age, sex, season, and provinces depending on some demographic and climatic aspects.MethodsThis study is retrospective and includes reported cases of infections using the available surveillance database taken from the Iraqi Ministry of Health for the years 2011, 2012, and 2013 for all provinces of Iraq.ResultsMen and boys were found to be at higher risk for CL compared with women and girls. The majority of cases were recorded among those in age groups 5–14 and 15–45 years old. Most cases were recorded from lowla
... Show MoreLeishmaniasis is a transmissible infection brought about by an obligatory intracellular protozoan from the genus Leishmania. It occurs worldwide in tropical and subtropical regions and can be burdensome in resource-constrained countries. The infection ranges in severity from mild cutaneous lesions to more severe and sometimes life-threatening visceral and distorting mucocutaneous sicknesses. Importantly, cutaneous leishmaniasis (CL) is prevalent in the Middle East with a pooled prevalence of 12%. It imposes a significant health and socioeconomic burden
Phlebotomus papatasi sand fly is the main vector of Zoonotic Cutaneous Leishmaniasis (ZCL) in Iraq. The aim of this study was to assess and predict the effects of climate change on the distribution of the cutaneous leishmaniasis (CL) cases and the main vector presently and in the future. Data of the CL cases were collected for the period (2000-2018) in addition to sand fly (SF) abundance. Geographic information system, R studio and MaxEnt (Maximum entropy niche model) software were used for analysis and predict effect of (elevation, population, Bio1-19, and Bio28-35) on CL cases distribution and SF occurrence. HadGEM2-ES model with two climate change scenarios, RCP 4.5 and RCP 8.5 were used for future projections 2050. The results showed th
... Show MoreThe study included 176 patients attended to Iben AL-Haithem hospital of ophthalmology in Baghdad city , at age of (14-77) years from the period from September 2016-April 2017, there were 138(78%) patients having a positive culture of ocular bacterial infections. Men were representing 41% while women 59%, the patients with bacterial ocular infection from Baghdad were55% while the internally displaced were 45% , the patients with ocular bacterial infections were representing 20% at mean age of 21.6±0.3y, 26% at 37.5±0.21y , 24% at53.5±0.23 y and 30% at69.5±0.10 y. The results showed 37% of the patients with ocular bacterial infections were having a history of diabetes mellitus and 44% with high blood pressure at mean age of 69.5±0.10
... Show MoreBackground: Urinary tract infection (UTI) is the most common bacterial infection in women in general and in postmenopausal women in particular. Bacteriuria occurs more often in elderly functionally impaired women but in general many of it are asymptomatic.However the risk factors associated with recurrent UTI in elderly women are not widely described.Bacteuria in elderly women is associated with high mortality rates ,however many of thus bacteriuria are asymptomatic (Assel et al.,2009).The belief that diabetes ,a common metabolic disorder is associated with ahigher risk of UTI is widespread,diabetes result in several abnormalities of the host defense system that might result in a higher risk of certain infection.
Patient and Method: T
Leishmaniasis is a global illness that is endemic in many countries, including Iraq. The characteristic of cutaneous leishmaniasis (CL) is the development of skin ulcers that are controlled by the immune system. Tumor necrosis factor-alpha (TNF-α), a cytokine generated by the innate immune response to CL infection, can influence disease clearance in the human host. The effect of this pro-inflammatory cytokine in CL ulcer development during the infection is not well established. In this study TNF-α level was detected in the patients who suffered from cutaneous leishmaniasis. This level was also assessed in the newly diagnosed patients and others who were undergoing different stages of pentostam treatment. Notably the result
... Show MoreLeishmaniasis diseases constitute an important public health problem in both tropical and subtropical areas. The aim of this study is to evaluate the epidemiological situation of cutaneous leishmaniasis (CL) in Babylon province, Iraq. The current work included the recording of 142 new cases of CL infection in Babylon province for the period from November 2019 to February 2020. Male infection was represented by 87 cases (61.27%), while females composed 55 samples (38.73%), with a significant difference (p<0.05) between the two groups. The age group of 5-14 years was found to have the highest recorded CL cases (56; 39.44%), while the age group of less than one year had the lowest cases (1; 0.70%), with the differences
... Show MoreForty five wound specimens were collected from patients suffering from wound infections and taken from various hospitals in Ibb city, Yemen. The study was to determine synergic antibacterial activity of between mountain honey and Argemone mexicana plant. Isolation, identification of bacterial isolates and antibiotic sensitivity test were done. Agar-disc and agar-well diffusion method were carried to determine antibacterial activity of honey, Argemone mexicana plant and a mixture of them against bacterial isolates. Out of 45 specimens, 29 (64.4%) gave positive cultures. Staphylococcus aureus was the predominant bacterial pathogens with percentage (72.4%) followed by Pseudomonas aeruginosa (17.2%) and Staphylococcus epidermidis (10.4%).
... Show More