Background: Dyslipidemia is a major cause of
cardiovascular disease, which in turn, is the most
common cause of female morbidity and mortality.
Postmenopausal women (natural and surgical) are at
higher risk of developing cardiovascular disease,
especially coronary artery atherosclerosis.
Objective: To observe the relationship between blood
lipids: total cholesterol (TC), high density lipoproteincholesterol (HDL-C), low density lipoproteincholesterol (LDL-C), triglycerides (TGs), and very low
density lipoprotein- cholesterol (VLDL-C), LDL-C/
HDL-C ratio (atherogenic index) and menopausal
status, and to determine the co-factors that may explain
this relationship
Methods: A prospective, cross-sectional study, which
includes 279 women, age range from 35-55 years
agreed to participate in this study. They were divided
into 4 groups according to their menopausal status.
These were pre-, peri post- natural and surgical postmenopausal. Data were collected from participants in a
pre-coded questionnaire and an overnight fasting blood
sample was collected for biochemical analysis.
Results: Postmenopausal women had higher levels of
lipids than pre or peri-menopausal. TC concentration
and LDL-cholesterol levels were higher in natural and
surgical menopause than in pre and pri-menopausal
women (p<0.01 and p<0.05 respectively). While
LDL/HDL-C ratio (atherogenic index) were higher in
the surgical postmenopausal women than in premenopausal group (p<0.05). No significant inter-group
differences were found in HDL-C. Triglycerides, and
VLDL levels were higher in surgical menopause group
than in both pre- and peri-menopause groups (p<0.05).
No significant differences were demonstrated in pre-,
peri-, and natural menopausal women with regard to
triglyceride and VLDL levels and LDL/HDL-C ratio.
Conclusion : Dyslipidemia is more frequent among
women with natural and surgical menopause groups
than in the other groups. This makes those women
more susceptible to CVD. Certain co factors appear to
have direct associations with lipid levels in each group
and those were discussed.
Summary
Praise be to God, Lord of the Worlds, and prayers and peace be upon the Master of the Messengers, Muhammad, and upon all his family and companions.
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... Show MoreMn2+ and Ce3+ Doped ZnS nanocrystals were prepared by a simple microwave irradiation method under mild condition. The starting materials for the synthesis of Mn2+ and Ce3+ Doped ZnS P nanocrystals were zinc acetate as zinc source, thioacetamide as a sulfur source, manganese chloride and Cerium chloride as manganese and cerium sources respectively (R & M Chemical) and ethylene glycol as a solvent. All chemicals were analytical grade products and used without further purification. The nanocrystals of Mn2+ and Ce3+ Doped ZnS P with cubic structure were characterized by X-ray powder diffraction (XRD), the morphology of the film is seen by field effect scanning electron microscopy (FESEM). The composition of the samples is analyzed by EDS. The s
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