Background: Polycystic ovary syndrome (PCOS) is the most common endocrinopathy affecting women, at reproductive age. PCOS is a chronic hyperandrogenic state that has many significant short-term and long-term implications for patients such as oligomenorrhea, amenorrhea, infertility, diabetes mellitus, cardiovascular disease, increased risk of endometrial cancer, and hirsutism. Objectives: To evaluate the obesity and glycemic criteria among women with polycystic ovary syndrome. Method: A case control designed study was carried out at the National Diabetes Center (NDC) / Al-Mustansiryia University; on 50 participants formed the PCOS group and 50 healthy control participants. Data collected about age, age at menarche and BMI. Also, blood samples examined for FPG and 2-h OGTT test carried out for all the participants. Moreover hormonal assessment for the LH, FSH and total testosterone were done for all participants. Results : PCOS group women age and age at menarche were 27.62 ± 5.74 and 12.0 ± 1.06 years; vs. the control group were 25.42 ± 4.94 and 11.64 ± 0.69 years respectively. All PCOS group were experienced signs and symptoms of ovarian dysfunction, and infertility while the control group did not experience any of such evidences. BMI showed significant difference between study groups (t-test (P < 0.05)); 98% of the PCOS group was obese vs. 58% of the control group. The waist/hip ratio showed insignificant difference (t-test (P > 0.05). Fasting plasma glucose (FPG) showed insignificant difference between the study groups (t-test (P >0.05); about 18% of the PCOS group was prediabetic (Impaired Fasting Glucose, IFG) (100-125mg/dl) and 6% was diabetic (>126mg/dl) whereas the entire control group was normoglycemic. The OGTT showed significant difference between the study groups (ttest (P < 0.05)); about 22% of the PCOS group was prediabetic (Impaired Glucose Tolerance, IGT) (140- 199mg/dl) and 6% was diabetic (>200mg/dl) whereas the entire control group was normoglycemic. PCOS group showed highly significant elevation in the LH level vs. the control group by about four folds (t-test (P < 0.05)). Also, FSH showed similar elevation by about two folds among the PCOS group vs. the control group (t-test (P < 0.05)). Moreover the LH/FSH ratio was elevated by about two folds among the PCOS group vs. the control group (t-test (P < 0.05)). Total serum testosterone of the PCOS group showed significant raise vs. the control group (t-test (P < 0.05)). Whole the PCOS group had A total testosterone level >60 ng/dL and in contrary the entire control group didn't show any elevation >60ng/dl. Conclusion: obesity of android (central) type was frequent and prevalent among PCOS women. About 20-28% of PCOS women was prediabetic or diabetic due to insulin resistance and decreased insulin sensitivity. Hormonal assay of LH, FSH, LH/FSH ratio and total testosterone were all significantly elevated by two folds or more among the PCOS women. It is not essential that a woman who had polycystic ovaries by ultrasound to have PCOS
The increasing use of plastics in various aspects of modern life resulted in the availability of enormous amount of wastes, including a negative effect on the environment and humans. So it is necessary to find solutions to deal with these wastes and ensure to use them as solutions to use in concrete mix . In this research the production of concrete containing high and low density polyethylene has been used by (5, 10, 15)% as a replacement of part of the volume of sand, so as to obtain concrete good compressive strength as well as other benefits such as improved possibility of pumping concrete and reduce the loss of concrete for workability polymer is a material that is non-absorbable of water . It is also intended to dispose of these was
... Show MoreThe main aim of the current research is to focus the light on some bacterial contamination on cracked eggshell and egg content plus studying the sensitivity of these bacterial isolates to antibiotics. For this purpose, a total of 50 eggs were collected from the markets in Baghdad city (Iraq) and examined for bacterial isolation from cracked eggshells and from the egg contents. The bacterial isolates were cultured and purified then transferred to a specific media to study its sensitivity against antibiotics. The results revealed that bacteria isolated from both cracked eggshells (46%) and egg contents (44%). The bacteria isolated include E. coli, Staphylococcus, Enterococcus faecalis, Enterobacter and Pseudomonas. The results of antibiotic s
... Show MoreBackground: Chemotherapeutic medication treatment for cancer is typically used in conjunction with other techniques as part of a routine regimen. It is well established that the capacity of different chemotherapeutic drugs to induce apoptosis is correlated with their anticancer efficacy. Quinazolinone-based drugs have demonstrated excellent responses from several cancer cell types. These substances have a lot of potential for use as building blocks in the creation of apoptosis inducers. Objective: To assess the new quinazolinone derivatives (M1 and M2) that were recently synthesized for their potential to halt wound healing and to use the acridine orange/propidium iodide (AO/PI) double stain to assess their capacity to induce apopto
... Show MorePolyaniline organic Semiconductor polymer was prepared by oxidation polymerization by adding hydrochloric acid concentration of 0.1M and potassium per sulfate concentration of 0.2M to 0.1M of aniline at room temperature, the polymer was deposited at glass substrate, the structural and optical properties were studies through UV-VIS, IR, XRD measurements, films have been operated as a sensor of vapor H2SO4 and HCl acids.
Pulsatile drug delivery systems are time-controlled dosage forms which are designed to release the active pharmaceutical ingredient after a predetermined lag time to synchronize the disease circadian rhythm. A migraine shows circadian rhythm with a marked increase in attacks between 6 a.m. and 8 a.m.
Sumatriptan is a selective agonist at serotonin (5-Hydroxy tryptamine1 (5-HT1))receptors, is an effective treatment for acute migraine attacks.
The aim of this work is to prepare time-controlled press-coated tablet with a lag time of 5.45 hrs.
Six formulas of fast dissolving core tablets and three formulas of press-coated tablets were prepared by using direct compression method using different variables to prepa
... Show MoreThis research involves studying the influence of increasing the
number of Gaussian points and the style of their distribution, on a circular exit pupil, on the numerical calculations accuracy of the point spread function for an ideal optical system and another system having focus error of (0.25 A. and 0.5 A. )
It was shown that the accuracy of the results depends on the type of
distributing points on the exit pupil. Also, the accuracy increases with the increase of the number of points (N) and the increase of aberrations which requires on increas (N).
This research is determined by the study of the " cognitive references of the directorial imagination and modeling of the theatrical actor performance ." it has described an Iraqi theatrical model, The research began with the great importance of the director's imagination as the basic premise for crystallizing the director's vision according to its cognitive references in creating a solid performance model based on the aesthetic, intellectual and technical bases, It is also contributes to the formation of the theatrical show as a technical framework that presents the show in one unified fabric.
The research sought to reach through the problem of research, which is in the question of: What is the modeling of the
... Show MoreIn this work, magnesium aluminate spinel (MA) (MgO 28 wt%, Al2O3 72 wt%) stoichiometric compound , were synthesized via solid state reaction (SSR) Single firing stage, and the impact of sintering on the physical properties and thermal properties as well as the fine structure and morphology of the ceramic product were examined. The Spinel samples were pressed at of (14 MPa) and sintering soaking time (2h). The effect of adding oxide titania (TiO2) was studied. The obtained powders were calcined at a temperature range of 1200 and 1400 °C. The calcined samples spinel were characterized by XRD, it showed the presence of developed spinel phase end also showed that the best catalyst is titania. The SEM image showed the high sintering temperat
... Show MoreThe banking system considered as one of the most important intermediate circle between creditor and debtors it is mean the most important funding rings in economic activity, whether finance takes the a consumer or investment form and therefore it is the main base to stimulate economic activity both on the demand side, both consumption and investment and therefore of the main motivating factors for economic growth.
The banking system depends in achieve its goals on the grants and loan recovery, or what is known credit process and according to what the importance referred to the role of the banking system, it is important to ensure the safety and efficiency of the mechanisms of banking device and safety is
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