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jkmc-709
Manifestation and response of Laryngopharygeal reflux to treatment in Kurdistan -IRAQ
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BACKGROUND: In 1972 complete description of the
inflammation of posterior third of the vocal cords was
done, with barium swallow confirming Gastro
Esophageal Disease [CRED] & subsequent successful
symptomatic treatment with antacid. The possible
association between GERD & chronic laryngitis was
initially known as acid laryngitis .2
*from the Department of ENT, Hawlear Medical College, Hawlear university. Department of ENT, Rezgary Teaching Hospital, Erbil.
Correspondence to :
Dr.Said Mustafa Said
Corespondence Address to : Dr.Said Mustafa Said _ E- mail: Email [email protected] Mob. 07504563829
Recived at : 15 th Dec 2009 Accepted at : 3ed Nov 2010

OBJECTIVE: To record the common presentation
symptoms of laryngopharyngeal reflux LPR in
Kurdistan- Iraq. To study the significance of fibro optic
laryngoscope in diagnosis and improvement of
laryngopharyngeal reflux [LPR] and to evaluate the
effect of medical therapy on these nonspecific
symptoms and Laryngoscopic finding.
METHODS: A prospective study was conducted over
a two year period at Rizgary teaching hospital,
Kurdistan/lraq; on 132 patients who presented
primarily with Laryngopharyngeal symptoms .They
were evaluated using special questionnaire for
recording these symptoms: persistent chronic cough,
globus sensation, throat clearing, voice change,
regurgitation, heartburn, symptoms of peptic ulcer
disease, and any other non specific respiratory
symptom. These symptom and Laryngoscopic findings
pre and post anti-reflux therapy were recorded.
Esophagogastro - duodenoscopy findings were also
recorded but only on presentation.
RESULTS: A total of 132 patients were evaluated over
a two year period .Respiratory symptoms at
presentation were persistent irritative cough [92%],
itchy throat [85%], globus pharynges [83%], and
cricopharngeal spasm [57%]. Endoscope findings
revealed gastroduodenitis in 5%, non specific gastritis
in 9%, duodenal ulcer in 2%, and normal findings in
62.7%, while Laryngoscopic finding were mainly
posterior commissure injection 82%, vocal cord edema
74%, laryngeal erythema 77% and subglottic edema
24%. Patients were treated medically with antacids, H2
antagonists, proton pump inhibitors and were followed
up and reexamined by laryngoscope; all data about
improvement in symptom and in the laryngeal sign by
Laryngoscopic findings were collected following antireflux therapy and showed significant improvement in
both ,all were analyzed in special figures and tables.
CONCLUSION: Reflux laryngitis and LPR should be
a differential diagnosis in patient with pharyngeal and
laryngeal symptoms not associated with upper
respiratory disease in the presence or absence of GERD
or peptic ulcer symptom, dyspepsia, regurgitation. The
management should be multidisciplinary.
Laryngoscopic finding were of value in the diagnosis of
the changes in laryngeal mucosa pre and post medical
treatment by Proton Pump Inhibitors empirical therapy

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Publication Date
Wed Oct 17 2018
Journal Name
Journal Of Economics And Administrative Sciences
The requirements of agricultural investment in Iraq in light of his accession Of the World Trade Organization
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Abstract              
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A Role of Therapy that Targets Immune Checkpoint Proteins for the Treatment of Melanoma Brain Metastasis, Liver, Breast, Pancreatic Cancer and Pancreatic Adenocarcinoma
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Checkpoint inhibitors are a type of immune therapy used to treat different types of cancers. These drugs block different checkpoint proteins, for example, CTLA-4, PD-1, and PD-L1 inhibitors.

They block proteins that stop the immune system from attacking the cancer cells.  Checkpoints are also described as a type of monoclonal antibody that antagonizes binding between B7 to CTLA-4 and PD-L1 to PD-1.

 Immune checkpoint inhibitors are used to treat BARCA mutated triple-negative breast cancer (TNBCS) in patients who do not respond to chemotherapy, and also in the treatment of highly mutated and solid tumors such as brain tumors, liver, and pancreatic cancers.

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Mon Jun 01 2020
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Non-polio Enterovirus Isolation in children with acute Flaccid Paralysis in Iraq
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Sun Nov 01 2015
Journal Name
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Topical 40% Loranthus europaeus Ointment Versus Topical 25% Podophyllin Solution in the Treatment of Acute Cutaneous Leishmaniasis (Single Blinded, Therapeutic, Comparative study)
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Tue Dec 30 2025
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Effect of small cardamom extracts on Mutans streptococci and Candida Albicans in comparison to chlorhexidine gluconate and de-ionized water (In vivo study (
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Publication Date
Sat May 11 2024
Journal Name
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The prevailing leadership Patterns and personal traits and their relationship to innovative thinking of female physical education teachers in middle schools in Baghdad
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Teachers play a critical role in planning, organizing, coordinating, monitoring, and instructing, hence the topic of leadership styles receives a lot of attention. As a result, the physical education school is regarded as the most significant component of the educational process because it has the ability to weave together the teaching and educational skills, attitudes, and capacities that its students develop. Fits into their identities through her relationship with them. Teachers play a critical role in planning, organizing, coordinating, monitoring, and instructing, hence the topic of leadership styles receives a lot of attention. As a result, the physical education school is regarded the most significant aspect in the educational proces

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