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jkmc-702
The Influences of Aminophylline and Indomethacin in Glycerol-Induced Acute Renal Failure in Rats
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Background: Adenosine mediates homodynamic
changes and resulted in the production of acute renal
failure (ARF) in female Albino-Wister rats, therefore,
adenosine level increases highly in ARF.
Objective: This experiment was designed to
investigate the effect of the adenosine antagonist
aminophylline and the adenosine agonist indomethacin on glycerol-induced ARF.
Method: Glycerol induced ARF was produced by a
single dose (10ml/kg, 50%v/v with distilled water i.m)
in rats, which were restricted to drinking water.
Aminophylline was used in our study in a dose of
25mg/kg, i.p) while the dose of indomethacin was
10mg/kg, i.p), assessment of renal function was done
by measuring blood urea
nitrogen (BUN), serum creatinine (Scr), and creatinine
clearance (Ccr)
Results: Aminophylline exert its protective effect
against glycerol induced-ARF by lowering the
elevation in concentrations of BUN, Scr, and mortality
rate with a markedly attenuation of the sever
impairment Ccr. On the other hand, indomethacin
potentiates glycerol induced-ARF by significantly
increase the elevation in concentrations of BUN, Scr
and mortality rate with severely suppressed the
decrement in Ccr.
Conclusion: Aminophylline has ameliorating effect on
glycerol induced ARF while the prostaglandin inhibitor
indomethacin has reversed effect

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Publication Date
Tue Oct 01 2019
Journal Name
Journal Of Economics And Administrative Sciences
الادارة بالرؤية المشتركة وانعكاساتها على التسويق الابداعي بحث استطلاعي لعينة من موظفي الشركة العامة للصناعات الكهربائية
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ان السبب الرئيسي لاختيار الموضوع كونه من الاساليب الادارية الحديثة التي تهدف الى انجاح المنظمة او الشركة المبحوثة, اذ تمثلت مشكلة البحث في ما دور الادارة بالرؤية المشتركة في تعزيز التسويق الابداعي بالشركة المبحوثة, يهدف البحث الى تسليط الضوء على مفهوم الادارة بالرؤية المشتركة وانعكاساتها على التسويق الابداعي للمنظمة ، باعتبارها منهج اداري حديث يسهم في تغيير وتجديد وتطوير واقع المنظمة المبحوثة( الشرك

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