BACKGROUND : Bifurcational coronary lesions are
frequent and amounts to almost one fifth of routine
practice concerning up to 15 – 20 % of cases .
Revascularization by percutaneous coronary
intervention ( PCI ), of bifurcational lesion has
become easier by stenting yet it remains a frequent
challenge.
OBJECTIVE : To evaluate the success and hospital
complications of two most frequent technique of stent
deployment in bifurcational PCI.
METHODS : We prospectively analysed the data of
140 consecutive patients with bifurcational PCI at
Ibn_Al-Bitar Hospital for cardiac surgery for the
period from July 2008 to July 2009 .
Depending on whether the side branch was stented or
not, the patient has fallen into two groups : -
Group A; stenting of the main vessel and angioplasty
of the branch.
Group B; stenting of both main vessel and its branch .
The early outcome of the bifurcational PCI and all
complications during hospitalization that include;
death, acute Myocardial infarction , emergency
percutaneous treatment and coronary artery bypass
graft (CABG) were evaluated in the studied groups.
RESULTS : The studied sample consisted of 140
patients,107(76.3%)were male and 33(23.7%) were
female. Group A consisted of 90 patients (64.3%)
while group B consisted of 50 patients(35.7%).Acute
procedural success was (94.2%) in group A and (80%)
in group B while hospital major adverse cardiac
event(MACE) were noted in 3.8% of group A and
20% of group B,(PV=0.04)
CONCLUSION: In bifurcational PCI stenting of the
side branch has made no extra advantage in term of
procedural success and early outcome.
Antibiotic resistance has been a growing worldwide public health issue. The World Health Organization (WHO) has stated that the search for new antibiotics is slow, while antibiotic resistance is growing. WHO has also declared that antibiotic resistance is one of the top 10 global public health threats facing humanity in the 21st century. Therefore, this review discusses the potential of metal-based drugs as antibacterial agents from the period of the early 2000s to date. The review reveals that a lot of preliminary work has been done to assess these as potential drugs. However, their mode of action is faintly described. Furthermore, a few examples of metal-based drugs assessed for their modes of action are described. These compounds are ide
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... Show Moreالوصف A simple chemistry method approach was used to synthesise new ligand derivate from L-ascorbic acid and its complexes. All of them were water-soluble and are used quite extensively in the medical and pharmaceutical fields. This study synthesised the new ligand derivative from L-ascorbic acid-base using the following steps: A 5, 6-O-isopropylidene-L-ascorbic acid was prepared by reacting dry acetone with L-ascorbic acid followed by reacting it with trichloroacetic acid to yield [chloro (carboxylic) methylidene]-5, 6-O-isopropylidene-L-ascorbic acid in the second stage. In the third stage, the derivative was reacted with (methyl (6-methyl-2-pyridylmethyl) amine to create a new ligand (ONMILA). This novel ligand was identified using
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