Background: Asymptomatic bacteriuria (ASB) is
defined as isolation of a specified quantitative count
of bacteria in an appropriately collected urine
specimen from an individual without symptoms or
signs of urinary tract infection.
Aim of study: To evaluate the frequency of
bacteriuria according to age, pregnancy, and type II
diabetes mellitus in a sample of Iraqi women.
Patients and Methods: A total of 125 female
individuals were involved. The study participants
were classified into the following groups: nonpregnant
women with type II diabetes mellitus,
pregnant women with type II diabetes mellitus,
pregnant women without type II diabetes mellitus, and
apparently healthy non-pregnant women. Urine and
blood specimens were tested to record positive urine
culture, pyuria, and blood glucose according to
standard microbiological and biochemical methods.
Results: Frequency of positive urine culture and
pyuria in the total pregnant women was 7 (14%) and
15 (30%), respectively, whereas frequency of positive
urine culture and pyuria in the total diabetic women
was 8 (16%) and 23 (46%), respectively. The bacterial
isolation rate in the studied groups was 13 (10%). Ecoli
recorded the highest isolation rate, 6(5%). There
was no significant culture positive of urine specimens
in the groups of diabetic non-pregnant, diabetic
pregnant, and women with normal pregnancy (Pvalue<
0.05). Pregnant women with culture positive
urine and pyuria were more likely to have perinatal
mortality. Sterile pyuria was detected in pregnant
women aged 18-45, those in third trimester, and in
multiparous pregnant women. There was significant
positive urine culture and a highly significant pyuria
in diabetic women with BMI > 25.
Conclusions: Asymptomatic bacteriuria is an
independent risk factor for perinatal mortality. Sterile
pyuria is a significant observation in pregnant and
diabetic women; therefore it should bring more
attention.
Recommendations Treatment of asymptomatic
bacteriuria is appropriate for pregnant women but it is
not recommended for diabetics. The study advised to
perform urine culture as a part of the antenatal checkup
for pregnant women.
The clinical spectrum of cutaneous leishmaniasis (CL), an intracellular parasitic pathogen, ranges from a single sore healing to chronic crusty lesions with a manifestation of treatment resistance. The complicated interaction between Leishmania bodies and the early immune response, including innate and adaptive mechanisms, determines the evolution of nodules. This study examined the levels of the chemoattractant interleukin 8 (IL-8), pro-inflammatory nitric oxide (NO), and immunoregulatory macrophage inhibitory factor (MIF) in the serum of subjects recently diagnosed with cutaneous leishmaniasis, in parallel with patients being monitored during consecutive sodium stibogluconate (Pentostam) treatment. A total of 161 serum samples of newly di
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... Show MoreBackground: Malignant lymphomas represent about 5% of all malignancy of the head and neck region which can involve lymph nodes as well as soft tissue and bone of the maxillofacial region. Apoptosis is considered a vital component of various processes including normal cell turnover, proper development and functioning of the immune system. Inappropriate apoptosis is a factor in many human conditions including neurodegenerative diseases, ischemic damage, autoimmune disorders and many types of cancer. Expression of p53 Proteins in Hodgkin׳s and Non Hodgkin׳s lymphomas suggested that it can help in monitoring of patients and the markers may aid in controlling the progression of lymphoma and detect the degree of aggressiveness of the diseas
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