Background: Asymptomatic bacteriuria (ASB) is
defined as isolation of a specified quantitative count
of bacteria in an appropriately collected urine
specimen from an individual without symptoms or
signs of urinary tract infection.
Aim of study: To evaluate the frequency of
bacteriuria according to age, pregnancy, and type II
diabetes mellitus in a sample of Iraqi women.
Patients and Methods: A total of 125 female
individuals were involved. The study participants
were classified into the following groups: nonpregnant
women with type II diabetes mellitus,
pregnant women with type II diabetes mellitus,
pregnant women without type II diabetes mellitus, and
apparently healthy non-pregnant women. Urine and
blood specimens were tested to record positive urine
culture, pyuria, and blood glucose according to
standard microbiological and biochemical methods.
Results: Frequency of positive urine culture and
pyuria in the total pregnant women was 7 (14%) and
15 (30%), respectively, whereas frequency of positive
urine culture and pyuria in the total diabetic women
was 8 (16%) and 23 (46%), respectively. The bacterial
isolation rate in the studied groups was 13 (10%). Ecoli
recorded the highest isolation rate, 6(5%). There
was no significant culture positive of urine specimens
in the groups of diabetic non-pregnant, diabetic
pregnant, and women with normal pregnancy (Pvalue<
0.05). Pregnant women with culture positive
urine and pyuria were more likely to have perinatal
mortality. Sterile pyuria was detected in pregnant
women aged 18-45, those in third trimester, and in
multiparous pregnant women. There was significant
positive urine culture and a highly significant pyuria
in diabetic women with BMI > 25.
Conclusions: Asymptomatic bacteriuria is an
independent risk factor for perinatal mortality. Sterile
pyuria is a significant observation in pregnant and
diabetic women; therefore it should bring more
attention.
Recommendations Treatment of asymptomatic
bacteriuria is appropriate for pregnant women but it is
not recommended for diabetics. The study advised to
perform urine culture as a part of the antenatal checkup
for pregnant women.
Hormones, their receptors, and the associated signaling pathways make compelling drug targets because of their wide-ranging biological significance to study the role of asprosin in obese male patients with diabetic mellitus type II. ELISA method was used to assay asprosin and insulin. Blood was taken with drawn sample from 30 obese normal patients with age range (40-60) years, 30 diabetic patients with age range (40-60) years at duration of disease (1-5) years and 30 normal healthy patients. The mean difference between T2DM according to insulin % (23.8±0.6) was increased than the mean of IFG (17.7±1.0) (P 0.000). The mean difference between T2DM according to asprosin (122.1±21.8) was increased than the mean of IFG (51.4±2.7) (P 0
... Show MoreThis study was carried out to describe the gene expression of the micro RNA 122a gene with the development of diabetes in Iraq. The difference in gene expression between patients and healthy controls was properly considered. In this study, blood was isolated from 121 individuals divided into two groups as follows: 80 samples of diabetic patients and 41 samples from a healthy control. miRNA was isolated and transformed into cDNA, and the expression of mi122a was measured by qRT-PCR. The researchers looked at the relationship between age and gender and the occurrence of diabetes, as well as how they compared to controls. When comparing the mean gene expression level (Ct) of patient groups to the corresponding Ct means in the control group, th
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A cross-sectional study was conducted between November 1, 2024, and March 1, 2025, at the Endocrine and diabetes center in Baghdad City, Iraq, tar
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