Background: Laparoscopic cholecystectomy
has become the standard of care for the
elective management of cholelithiasis. Little
information exists, however, regarding the
appropriateness of this procedure in the setting
of acute symptomatology.
Objective: This study was designed to
evaluate the outcome of laparoscopic
cholecystectomy in acute and severe acute
cholecystitis based on early and late biliary
complications, their incidence and
management, and conversion rates to open
surgery.
Methods: A prospective study done between
April 2007 and November 2010, in the
department of general surgery, medical city
teaching hospital, Baghdad. Includes patients
with acute cholecystitis admitted for
laparoscopic cholecystectomy; they were
divided into two groups, (group 1) including
patients with acute cholecystitis; (group 2)
including patients with severe acute
cholecystitis.
Results: 306 patients were admitted for
laparoscopic cholecystectomy, 71 (23.2%) of
them with acute cholecystitis and was involved
in this study; they were divided into two
groups, (group 1) patients with acute
cholecystitis 61(85.9%), (group 2) patients
with severe acute cholecystitis 10 (14%);
including gangrenous gallbladder 3(30%), and
empyematous gallbladder 7(70%). Patients in
group 2 were significantly older than in group
1. Female sex was more significant in group 1,
while male sex was more significant in group.
There was no procedure related mortality.
Conclusion: laparoscopic cholecystectomy
for acute cholecystitis is safe and associated
with a low morbidity, mortality, and a low
conversion rate.
Many of the dynamic processes in different sciences are described by models of differential equations. These models explain the change in the behavior of the studied process over time by linking the behavior of the process under study with its derivatives. These models often contain constant and time-varying parameters that vary according to the nature of the process under study in this We will estimate the constant and time-varying parameters in a sequential method in several stages. In the first stage, the state variables and their derivatives are estimated in the method of penalized splines(p- splines) . In the second stage we use pseudo lest square to estimate constant parameters, For the third stage, the rem
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