Background Over the past decade there has been a growing awareness of, and interest in, the trace element concentration differences between normal and diseased tissues. Significant changes in tissue concentrations of Zinc (Zn) and Copper (Cu) have been previously reported in inflammation and cancer of certain human tissues.
Aim:(1)To correlate between Zn and Cu concentrations and the histological picture of normal and certain inflamed human tissues, namely the gall bladder (GB) the vermiform appendix (VA), visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT). (2) to detect whether there is a difference in the above-mentioned parameters between VAT and SAT. (3) to obtain recordings for trace element levels in human tissues.
Methods: Diseased GB (10), VA (10), VAT (10) near these organs and SAT (10) were removed by surgery. Tissues from these organs were then processed for histopathology and analyzed for trace elements concentration by Atomic Absorption Flame-Emission Spectrophotometer.
Results: Zn concentration was high in VAT (0.410 μg/g ± 0.181), GB (0.478 μg/g ±0.531) and VA (0.419 μg/g ±0.123) when compared to its level in SAT (0.1329 μg/g ± 0.0129) and the difference was significant (<0.007,<0.056 and <0.000 respectively).
Cu concentration was high in VAT (0.640 μg/g ± 0.150) and GB (0.919 μg/g ± 0.564) when compared to SAT (0.3893 μg/g ± 0.0130) and the difference was significant (<0.005 and <0.011 respectively). Cu concentration in the VA was low (0.2055 μg/g ±0.0654) and significantly different from all the other tissues (VA vs VAT <0.000, VA vs GB <0.002 and VA vs SAT <0.000).
The histology findings were typical of chronic inflammatory reactions in the GB and of acute inflammation in the VA.
Conclusions: The increase in tissue concentrations of Zn in VAT, GB & VA is due to inflammation.
The high Cu level in chronically inflamed GB and neighboring VAT is due to the increased need for this element during inflammation.
Our results, together with findings reported by others, allow us to think of using trace elements, namely Zn and Cu, as tools for diagnosis and treatment in appropriate conditions.
In the field of implantology, peri-implantitis is still a common complication of implant failure. Similar to periodontal disease, this kind of pathological condition is characterized by inflammation of the tissues surrounding dental implants or fillings. The sources of infection have been shown to be chronic periodontitis and poor maintenance of the communion. A thorough examination of the intricate components of peri-implantitis was sought in this review in order to identify common characteristics of the disease with regard to bacteria, biofilm formation, host immunological responses, diagnostic tools, and therapeutic treatments. The aim of this study was to provide a detailed overview of the different bacterial species associated
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This study aims to deeply analyze the character of serial killers in Thomas Harris’ novels and focuses on his novel Red Dragon. The Study searches in these complex and deep characters through the use of Erich Fromm's concepts about the destructive nature of the human psyche and what are the factors affecting serial killers in all social psychological, and biological aspects. This study Concluded: Thomas Harris portrayed the characters of serial killers in a professional and complex and made the reader go on a contemplative journey in the mind and soul of the serial killer, thus reaching the climax of artistic perfection.
Psychosocial Alienation is a modern concept that arises from the capitalist and materialistic conceptions of individuals. The evergrowing competitive nature of domestic societies crystallised the concept in its modern form. The intensity of the rapid changes in the urbanised societies prevents the individuals from exploring their inner selves. Thus, a new generation is created with an alienation crisis which is reflected inward towards the self and outwards toward society. Alan Ayckbourn (1939), A British playwright, presents Alienated characters inspired by his life on and off stage. He explores their Alienation and their path toward recovery and self-realization. A Brief History of Women (2017) Ayckbourn explores the depth of the individu
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Suggestion Plan for the Reclassification of U.N Publications in Central Library