Background Over the past decade there has been a growing awareness of, and interest in, the trace element concentration differences between normal and diseased tissues. Significant changes in tissue concentrations of Zinc (Zn) and Copper (Cu) have been previously reported in inflammation and cancer of certain human tissues.
Aim:(1)To correlate between Zn and Cu concentrations and the histological picture of normal and certain inflamed human tissues, namely the gall bladder (GB) the vermiform appendix (VA), visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT). (2) to detect whether there is a difference in the above-mentioned parameters between VAT and SAT. (3) to obtain recordings for trace element levels in human tissues.
Methods: Diseased GB (10), VA (10), VAT (10) near these organs and SAT (10) were removed by surgery. Tissues from these organs were then processed for histopathology and analyzed for trace elements concentration by Atomic Absorption Flame-Emission Spectrophotometer.
Results: Zn concentration was high in VAT (0.410 μg/g ± 0.181), GB (0.478 μg/g ±0.531) and VA (0.419 μg/g ±0.123) when compared to its level in SAT (0.1329 μg/g ± 0.0129) and the difference was significant (<0.007,<0.056 and <0.000 respectively).
Cu concentration was high in VAT (0.640 μg/g ± 0.150) and GB (0.919 μg/g ± 0.564) when compared to SAT (0.3893 μg/g ± 0.0130) and the difference was significant (<0.005 and <0.011 respectively). Cu concentration in the VA was low (0.2055 μg/g ±0.0654) and significantly different from all the other tissues (VA vs VAT <0.000, VA vs GB <0.002 and VA vs SAT <0.000).
The histology findings were typical of chronic inflammatory reactions in the GB and of acute inflammation in the VA.
Conclusions: The increase in tissue concentrations of Zn in VAT, GB & VA is due to inflammation.
The high Cu level in chronically inflamed GB and neighboring VAT is due to the increased need for this element during inflammation.
Our results, together with findings reported by others, allow us to think of using trace elements, namely Zn and Cu, as tools for diagnosis and treatment in appropriate conditions.
The new Schiff base 1‐[(2‐{1‐[(dicyclohexylamino)‐methyl]‐1H‐indol‐3‐yl}‐ethylimino)‐methyl]naphthalen‐2‐ol (HL) was prepared from 1‐{[2‐(1H‐Indol‐3‐yl)‐ethylimino] methyl}‐naphthalen‐2‐ol and dicyclohexyl amine. From this Schiff base, monomeric complexes [M (L)n (H2O)2 Cl2] with M = Cr, Fe, Mn, Cd, and Hg were synthesized and characterized based on elemental analysis (EA), FT‐IR, mass(MS), UV‐visible, thermal analysis, magnetic moment, and molar conductance. The results showed that the geometrical structural were octahedral geometries for the Cr(III) and Fe(III) complex
The research aims to identify the impact of managing performance's employees in building intellectual capital, Because employing the practice of managing the performance of employees may acquire familiar skills to improve their performance and reflect on the construction of intellectual capital in the surveyed area, Especially that the independent dimension represented by the management of the performance of employees is one of the important topics that has received attention in the world of management in general and human resource management in particular. While the adopted dimension was represented by Intellectual capital in the important practice of human resource management in the increasing of their knowledge, to
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The research is important statement on the importance of big capital in the banking business and the attributes of a role in the absorption of losses suffered by the bank, which reflects the willin
The aim of this study is to explain methods to be followed for the recovery Alsnav Hor, who represents the northwest portion of the Hammar Marsh in the province of Dhi Qar, after the drought in which that happened in 2008. The study included description of the region before the drought, the description of its natural and human environments, the economic events and activities, then the study included drought throughout the region, the environmental impacts caused by drought, its impact on social reality, economic and healthy for its environment, and then reached to the problems of social and economic in the region, depending on the Field studies and documented in the specialized government departments, information analysis for the
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