Objective: Aimed to asses the role of PT estimation in early diagnosis and predicting the extent and the outcome of head injury with ICerH and/ or Contusion
Method :PT was measured by Digiclot 818
Group –1: One hundred consecutive head injured patients admitted at Neurosurgical and Al Ramadi teaching hospitals were initially estimated for prothrombin time and subsequently scanned
Group-2 : Two hundred twenty five consecutive non scanned head injured patients admitted to Neurosurgical and Al Ramadi teaching hospitals were estimated with prothrombin time at the time of insult and subsequently for the next two weeks Al – Kindy Col Med J 2012; Vol. 8 No. 1 P: 54
Clinical and neurological evaluation (GCS) score in addition to computerized tomography scan was done for both groups
Result :Group -1: Twenty eight (28%) of the initially estimated head injured patients had prolonged prothrombin time in which their subsequent CT scan revealed an ICer H and/or contusion
Seventy six (76%) percent of those with severely head injured patients (GCS≤8) were having an initial prothrombin time prolongation..While those with mild head injury (GCS≥12) only thirty (30%) of them were having the initial prothrombin time prolongation
Group-2 Those patients who survived the initial insult and subsequently thereafter (surgically or conservatively treated) even with a deficit.. Daily estimation of prothrombin time showed a decline within the 7-14 days
Those patients who finally died (surgically or conservatively treated) daily estimation of prothrombin time showed a persistent elevation or a fluctuation within the next 7-14 day
Conclusion Prothrmbin time is an important
parameter in :
1-Reflecting the severity of head injury (GCS)
3-Early detection of ICerH and /or contusion
2-Prognostic value in cases of of ICerH and /or contusion
Abb : ICerH = Intracerebral hematomas,SDH=subdural hematomas,EDH=epidural hematomas,SAH=subarachnoid hemorrhages,PT=Prothrombin time,Pts=Patients,CT scan=computarized tomography.
ackground An autoimmune and inflammatory illness called rheumatoid arthritis (RA) occurs when your immune system mistakenly attacks normal cells in your body. Interleukin-35 is a brand-new cytokine that belongs to the immunosuppressive and anti-inflammatory IL-12 family. β -herpesvirus that produces inflammation and stays dormant in its host for life is the human cytomegalovirus. Human herpesvirus (HCMV) has been at the core of several RA-related theories. Objective The current study looked at the association between RA and serum IL-35 levels as well as the association between RA and CMV. Patients and methods Blood samples were taken in the Baghdad Teaching Hospital and Typical Rheumatology Unit from January 2022 to Mars 2022 for the curre
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