Background: Obesity is becoming the healthcare epidemic world wide.Obesity is associated with reduced life expectancy, increased morbidity and mortality, and greater healthcare costs.Bariatric surgery is the only effective treatment for morbid obesity and is gaining increasing popularity. There has been a steady rise in the numbers and types of bariatric operations done worldwide in recent years butnon of prove to be ideal .Animal studies and use of animal models are significant element in the evolution of medical knowledge and the use of animals as a model for bariatric surgery is of importance to study the mechanisms of these operationsa and also help to develop new technique in management of obesity.Objectives:Study of effects of sleeve gastrectomy as bariatric surgery procedures on weight of dietary induced obese rats (DIO).Methods:Eighteen adult rats with diet induced obesity (DIO) divided into two groups, the first (n=9) group exposed to sleeve gasterectomy (SG)under general anesthesia , the second(n=9) is the sham (control) group. Postoperative care of the animals done as required and the weight of the rats were measured weekly for 6 weeks .Results:. Follow up for 6 weeks post-operative . Four rats from SG group were died: two in the first day , second and 6th post operative day .Postmortem done with evidence of gastric leak in two of them. Two sham operated rats were died. The dead rats were cancelled from the study when body weight calculated. Average weight were 425gram and 420gram for SG and Sham respectively before surgery. Both groups experience some weight loss in the first week after surgery while the SG group start losing more weight , while the sham group are starting to maintain its normal weight until the end of the experiment.Conclusions:. Sleeve Gastrectomy as a bariatric procedure are successfully reduce the weight of DIO rats . Development of animal model for bariatric procedure is of great importance to test the effects of different bariatric procedures on the weight, and translate these procedures on human.
In this paper, the impact of magnetic force, rotation, and nonlinear heat radiation on the peristaltic flow of a hybrid bio -nanofluids through a symmetric channel are investigated. Under the assumption of a low Reynolds number and a long wavelength, the exact solution of the expression for stream function, velocity, heat transfer coefficient, induced magnetic field, magnetic force, and temperature are obtained by using the Adomian decomposition method. The findings show that the magnetic force contours improve when the magnitude of the Hartmann number M is high and decreases when rotation increases. Lastly, the effects of essential parameters that appear in the problem are analyzed through a graph. Plotting all figures is done using the
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We study the physics of flow due to the interaction between a viscous dipole and boundaries that permit slip. This includes partial and free slip, and interactions near corners. The problem is investigated by using a two relaxation time lattice Boltzmann equation with moment-based boundary conditions. Navier-slip conditions, which involve gradients of the velocity, are formulated and applied locally. The implementation of free-slip conditions with the moment-based approach is discussed. Collision angles of 0°, 30°, and 45° are investigated. Stable simulations are shown for Reynolds numbers between 625 and 10 000 and various slip lengths. Vorticity generation on the wall is shown to be affected by slip length, angle of incidence,
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Background and Objectives: Wound healing is a complex process with overlapping phases haemostasis, inflammation, proliferation and maturation/matrix remodeling. Each phase of wound healing requires different management strategies, and inappropriate treatment can delay wound healing. The aim of the present study was to evaluate the efficacy of topical application of calmodulin as a significant augmentation of the granulation tissue production process of wound healing and to express of genes CaMKK2, MaP2K6 and CXCR4 at site of wound defect, that have versatile effects on the body and they belong to Ca/camodulin related genes. Material and Methods: In this study thirty albino male rats, weighting (300-400) gram, aged (6-8) months, wil
... Show MoreBackground: Wound healing is a complex dynamical interaction between various cell types, the extracellular matrix, cytokines, and growth factors. osteoponetin is a substance that acts as an anti-inflammatory. Aims of study: The study was designed to identify the role of local exogenous applications of osteopontin on wound healing (in cheek skin). Materials and methods: Thirty adult male albino rats weighting an average of (250-300gm) used in this study, incisional wounds were made in the skin of the cheek of rat and they were divided into the following groups: A-Control group: 15 rats treated with 1µ l of normal saline B-Experimental groups: 15 rats treated with topical application of 1µl osteopontin. The scarification of animals we
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Background: Postoperative pain is one of the main complications following impacted mandibular third molar (IMTM) surgery. Objectives: The aim of this study was to assess the effect of the local application of bupivacaine on reducing early postoperative pain following IMTM surgery. Material and methods: A prospective, single-blinded, randomized controlled study was conducted on 40 patients who had undergone the surgical removal of an IMTM under local anesthesia. In the study group (n = 20), absorbable gelatin sponge (AGS) soaked in 3 mL of 0.5% plain bupivacaine hydrochloride was locally applied in the post-extraction socket. In the control group (n = 20), AGS soaked in 3 mL of normal saline was used. Pain intensity was assessed using a pa
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The objective of this work was to determine and compare the physiological changes in some: blood components (packed cell volume and hemoglobin) and plasma biochemical parameters (glucose, total protein, albumin, cholesterol and triglycerides) under 3 day of different types of stress: water deprivation, starvation, overcrowding and handling stress. Twenty five male Wister rats weighted 100-120 gm, were divided randomly into five groups: control, water deprivation, starvation, overcrowding and handling stress. On the third day of stress the animals anesthetized for blood collection; the results of blood component revealed a significant increase in PCV and a significant decrease in Hb of water deprivation group and starva
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The weight of larvae virgins and Alcamlat for males more than the weight of females of the roles themselves that the highest rate of loss in weight of larvae developed to virgins when field conditions were (21.5,22,21.3) mg during June and July and August respectively, recorded the highest degrees of heat and less attributed to moisture