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Infectious Causes of Diarrhea Among Neutropenic Children
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Background: Intestinal infections are frequently occur among children with cancer who receive chemotherapy. On the other hand, diarrhea is especially common and severe among cancer patients that develop neutropenia, either due to the disease itself or due to the intensive chemotherapy. There are many causes of diarrhea among those patients, but intestinal infections still an important etiology among them.

Objectives: to study the frequency of diarrhea among neutropenic children, with its infectious etiologies, especially the bacterial, fungal and parasitic causes.

Type of the study:Cross-sectional study.

Methods: the study was done in the Oncology Department of Nanakali Hospital for Haematological diseases and malignanciesin Erbil City, on pediatric age group. One hundred six children with cancer were followed up during the period between January – May 2017, of them only 50 patients who full fill the criteria of being (neutropenic, diarrheic, and age < 14 years), and those were regarded as the study group, compared to 20 patients who had the same criteria (diarrheic, and age < 14 years) but notneutropenic.They were investigated for the infectious causes of diarrhea especially bacterial, parasitic, and fungal agents. Data were analyzed statistically using SPSS program and Correlation test was also used. The results were regarded significant with p < 0.05.

Results: A total of 70 diarrheal episodes in 106 cancer children were detected, 50 of them were neutropenic while 20 were not. Intestinal infections were detected in 62% of the 1st group and in 45% of the 2nd one, while the causes in the remaining cases of diarrhea (38%) cannot be identified. Bacterial pathogens were the main agents that causes diarrhea followed by fungi then parasites with an infectious rates of (28%, 20%, and 14% respectively).

Conclusions: Diarrhea commonly developed among cancer children with neutropenia. Bacteria are the most incriminated pathogens followed by Candida and parasites. This study noticed the presence of other etiologies for diarrhea beside infectious causes that should be considered and investigated in the future researches and during management of diarrhea in those patients.

 

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Publication Date
Sun Dec 05 2010
Journal Name
Baghdad Science Journal
Effect of Granulocyte-colony stimulating factor with or without Moxifloxcacin therapy on capsulated Staphylococcus aureus infection in neutropenic mice
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Twenty bacterial isolates were identified as Staphylococcus aureus collected from wounds and catheters related infections. A capsulated S. aureus isolate was chosen after performing serum soft agar test, for this study Neutropenic mice were challenged with capsulated S. aureus ,and the effect of G-CSF with or without moxifloxacin was studied. The results indicated that the addition of G-CSF to moxifloxacin therapy have a synergistic effect in the killing of the bacteria, while when each G-CSF and moxifloxacin were used seperately have a similar effect on bacterial killing. It was found that the moxifloxacin has the same activity as G_CSF but is less costly than the latter one.

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Publication Date
Fri Dec 20 2024
Journal Name
Journal Of Baghdad College Of Dentistry
Maximum bite force among a group of Iraqi children in relation to mandibular growth rotation
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Publication Date
Thu Nov 01 2018
Journal Name
Iraqi National Journal Of Nursing Specialties
Study on the Prevalence of Intestinal Parasites Among Children Attending Al-Daura Health Centre-Baghdad
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Abstract The present study on the prevalence of intestinal parasitic infection from July 2003 to July 2004 ,was conducted among children aged(less than 5 -14 )years attending AL-Daura Health Centre in Baghdad City .(350) specimen were choosen randomly and examined, 160(45.7%) of these were infected , 140 (87.5%) harboured one parasite while 20 (12.5%) harboured more than one parasite.190 (54.3%) were non infected with any of intestinal parasite . It was observed that the most common intestinal protozoa among children is Giardia lamblia, followed by Entamoeba histolytica and Blastocystis hominis with pre

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Publication Date
Fri Jun 11 2021
Journal Name
Journal Of Baghdad College Of Dentistry
Traumatic dental injuries in relation to quality of life among school children in Baghdad /Iraq
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Background: One of the significant public health problems is the traumatic dental injury to the anterior teeth, it has a great impact on children’s daily. Physical and psychological disturbance, pain and other negative impacts, such as tendency to avoid laughing or smiling may be associated with traumatic dental injuries, that may affect the social relationships. To determine the occurrence of traumatic dental injuries in relation to quality of life, this study was established among children of primary schools. Material and Methods: A cross-sectional study was conducted among private (574) and governmental (1026) primary school children in Baghdad city. Dental trauma was assessed according to Ellis and Davey classification in1970

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Publication Date
Sun Aug 13 2017
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
Prevalence of malnutrition among U5 children in Iraqi south governorate (Basrah, Thi Qar and Misan)
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The field work to study morbidity & nutritional status of 3828 child aged between 659 months in Basra, Misan and Thi Qar governorate.  The results indicated that 14%, 11.7% and 5.4% of the children suffer from diarrhea, Fever & Acute Respiratory Infection (API) respectively. While the prevalence of malnutrition for the children at the three governorate indicated that the chronic was 24.8%, 25.1% and 23%, general malnutrition was 17.1%, 21.4% and 22% where as the acute malnutrition was 9.2, 9.4 and 14.2 respectively.

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Publication Date
Mon Jun 30 2014
Journal Name
Al-kindy College Medical Journal
Epidemiological, Clinical, and immunological characteristics of Mycoplasma pneumonia infections among a group of hospitalized children in Suleimani city/Iraq
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Background: Mycoplasma pneumoniae (M. pneumoniae) is an important respiratory bacterial pathogen, especially among children. It causes acute upper and lower respiratory infections.Objective: This study was aimed to measure anti- M. pneumoniae antibodies among hospitalized children who were admitted to hospital diagnosed with acute respiratory tract infections.Method: Automated ELISA technique was performed to detect anti- M. pneumoniae antibodies (IgM and IgG antibodies) in serum from 108 children less than 5 years old. The children were admitted to the Pediatric Teaching Hospital in Suleimani city/Kurdistan Region/Iraq because of acute respiratory tract infections. A questionnaire was designed to collect demographic and clinical data fr

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Publication Date
Sun Jan 03 2016
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Aortic root dilatation among children with unoperated Fallot tetralogy. A clinical and echocardiographic study.
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Bacground: Tetralogy of Fallot (TOF) is a commn congenıtal heart disease and it may be associated with aortic root dilation (ARD ) before or even years after the surgical repair. To the best knowledge this is the first study in Iraq dealing with this issue.
Objectives : To dtermine the frequency of aortic root dilatation among sample of children with Fallot teralogy in Mosul-İraq and to asses its associated risk factors.
Patients and methods : A total of 110 children ,54 with TOF compared to 56 normal chıldren by echocardiography for determining the frequency of aortic root dilatation among both groups. Among TOF children different factors like age and sex, size of the ventricular sptal defect (VSD) ,degree of overrıdıng of ao

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Publication Date
Fri Jun 15 2018
Journal Name
Journal Of Baghdad College Of Dentistry
Oral Health Status among 9 years old school Children in Al-Diwaniyah City/Iraq.
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Background: Although they are not life threatening, dental caries and periodontal disease are the most predominant and widely spread oral diseases throughout the world. Another most common dental problem seen in children is dental trauma. The aims of the study included the investigation of the prevalence and severity of dental caries, gingivitis and dental plaque in relation to gender, furthermore, the prevalence and severity of the traumatized anterior teeth were assessed. Materials and Methods: This oral health survey was conducted among primary school children aged 9 years old in Al-Diwaniyah city in Iraq. The total sample composed of 600 child (320 males and 280 females) selected randomly from different school in Al-Diwaniyah city. Dia

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Publication Date
Mon Jan 01 2024
Journal Name
Scripta Medica
Eruption of first permanent molar among a group of Iraqi children in relation to nutritional status
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Background/Aim: The timing of a tooth's eruption can be affected by a variety of factors. The nutritional status has an impact on the development of a child's body. The purpose of the study was to analyse the number of children aged 6 to 9 in an Iraqi Arab population who had erupted permanent first molars and to examine how nutritional status affected the timing and level of emergence. Methods: A total of 330 boys and girls, in first grade elementary school, made up the sample. First molars that had erupted were noted, along with the level of the eruption. Each child's nutritional status was evaluated by recording their height and weight and body mass index (BMI) value was compared to the 2007 WHO reference. Results: Girls had highe

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Publication Date
Tue Jan 01 2019
Journal Name
Indian Journal Of Public Health Research &amp; Development
Prevalence of Depression among Mothers of Children with Type 1 Diabetes Mellitus attending two Diabetes Centers
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