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Acromegaly is a rare disease produce generalize and serious alteration in the patient with active disease. Many of these
patients are also diabetic. Many analytes, hormones, markers are change in these disease. The objective of study is to
assess the modification in a number of parameters that changed during the acromegaly as a result of excess in GH and IGF1 levels. The study included 36 patients and 38 healthy controls, paired by sex and age and BMI. Serum concentration of
GH and the other parameters including (insulin, glucose, lipid profile, uric acid ) were determined by biochemical method
.Compared to controls, acromegalic patients had increased levels of GH, insulin, glucose, triglyceride, very low density
lipoprotein(VLDL) (p<0.05)
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