The objective of this study was to determine the concentration of trace element chromium(III) and thyroid peroxidase activity in human serum , and to find a relationship between the concentration of chromium(III) and thyroid peroxidase activity in serum of patients with hypothyroidism, hyperthyroidism and healthy subjects. Serum thyroid peroxidase was measured by enzyme linked radioimmunoassay(ELISA) method and chromium determination was by atomic absorption spectrophotometer .Comparing the values of chromium concentration and thyroid peroxidase activity in both samples showed that there were significant positive correlations between chromium levels and thyroid peroxidase activity(P<0.01, r=0.11). The results showed that Serum thyroid peroxidase activity and chromium levels were significantly higher in hyperthyroidism patients (152.0±4.6 IU/L) (2.159±0.15 ppb) respectively than normal (51.0±1.8 IU/L) (0.378±0.024 ppb) respectively and lower than normal in hypothyroidism patients (35.0±0.31 IU/L)(0.099±0.011 ppb) respectively.
Background:The technology of nanoparticles has been expanded to many aspects of modern life. Titanium dioxide nanoparticles were of many nanomaterials utilized in biomedical applications. The interactions between nanoparticles and proteins are believed to be the base for the biological effect of the nanoparticles. The oxidation reaction of many substances is catalyzed by oxidizing enzymes called peroxidases. The activity of salivary peroxidase is elevated with periodontal diseases. the aim ofthis study is to examine the action of titanium dioxide nanoparticles on salivary peroxidase activity.Material and method75 participants were enrolled in this study—Periodontitis group with 44 participants and the non-periodontitis group with 31 pa
... Show MoreBackground: 18F-FDG positron emission tomography (PET) has established itself in the field of oncology and it is useful in the initial staging and follow-up of a variety of malignancies. Significant thyroid uptake is often identified as an accidental finding on whole-body positron emission tomography for non-thyroid disease.
Aim of this study: to investigate the effect of 18F-FDG on thyroid gland function after performing PET scan compared to thyroid function prior to scan.
Materials and Methods: 43 subjects who had an 18F-FDG PET scan as part of a cancer screening program participated in this study. All cancers are diagnosed using 18F-FDG, except for prostate cancer,
... Show MoreThe aims of the present study are to evaluate the levels of CA19-9 in sera and tissues' homogenate of breast and thyroid benign patients in order to assess its use as an early diagnostic parameter in differentiation between malignant and benign cases. The study was conducted on 8 patients with breast benign tumor and 8 patients with thyroid benign tumor, by the enzyme linked immunosorbent assay (ELISA) technique. The results of CA19-9 levels in sera were (15 ±1.58 and 10.67 ±2.08)U/ml respectively compared with serum CA19-9 levels of control group which was 7.74 ±4.92 U/ml, the results were found to be highly significantly in breast tumor patients and non significantly in thyroid
... Show MoreObjectives: study the relation between the effect of time (long time duration) with high concentration of iodine
and study its effect on the activity of the thyroid gland (hormonal and histological changes).
Methodology: An experimental study was done on (30) albino rats (8 weeks of age) to know the effect of high
concentration of iodine on the activity of the thyroid gland (hormonal and histological changes) related with
time. The study last for six months for the period of 1/2/2007 to 31/7/2007, the experiment was carried out in the
research lab. of pathology department, College of Medicine, University of Baghdad.
Results: The study shows changes in hormonal levels of thyroid hormones (T3 & T4) and also histologic
Background: thyroid carcinoma is the most common endocrine carcinoma as it accounts for almost 90% of all endocrine malignancies. The term incidental denoted malignant tumors of the thyroid gland detected by post-operative biopsy results of the resected specimens resected from benign thyroid diseases. Among the incidental thyroid malignancies, papillary carcinoma is the commonest pathological type.
Objectives : To determine the incidence of incidental thyroid carcinoma and to insist on accurate preoperative diagnostic work up of patients with thyroid diseases.
Patients & Methods: A prospective study, which was conducted during the period from March 2013 to April 2014 at Baghdad teaching hospital first surgical unit by the same
The thyroid gland is a vital part of the overall endocrine system, which is regulated some of body function as oxygen use, basal metabolic rate, growth, cellular metabolism and development This study shed light on a number of extracts that have been shown to have beneficial effects on the thyroid and its function, as well as the various factors linked to thyroid dysfunction. The experiment was conducted to determine the effect of a mixture of two extracts of "Fucus vesiculosus (150 mg/ kg) with Coleus forskohlii (1000 mg/ kg) and Rosmarinus officinalis (220 mg/ kg) with Camellia sinensis (1.25 mg/ kg)" on thyroid hormones as well as lipids profile and tested the effectiveness of two drugs one of them stimulates the hormones of the thyroid (
... Show MoreThis study aimed to determine the nickel (Ni), and chromium (Cr) ions amounts and investigate their potential effects on thyroid hormones in patients' saliva who were receiving treatment with fixed orthodontic appliances (FOA). In this study, 42 FOA volunteers participated, and all samples were obtained from a specialized center for manufacturing and orthodontics in Bab Al-Moadham, Baghdad, Iraq. According to the findings, individuals with fixed orthodontics have significantly higher levels of the thyroid hormones (P<0.05) FT3 and FT4 than those who did not have orthodontic treatment, whereas there were no significant changes in TSH (P=0.599). Additionally, the amounts of Ni+2 and Cr+3
... Show MoreThyroid carcinoma incidence is increasing yearly and ranks second among the top ten cancers in Iraq, especially among women. The single nucleotide polymorphism (rs965513, A>C) near FOXE1 gene was found to be associated with papillary thyroid carcinoma risk in several Genome-wide association studies. Therefore, this is a case-control study aimed at identifying whether this variation is associated with the risk of papillary thyroid carcinoma in the Iraqi population. Association of rs965513 was investigated in one hundred and one papillary thyroid carcinoma Iraqi patients and one hundred and two controls using quantitative PCR-high resolution melting technique. The results of genotype and allele frequencies showe
... Show MoreOne of the most common forms of diabetes is Type-2 that occurs due to the failure of cells in recognizing and responding to insulin if not accurately treated. The aim of this work is to evaluate the relations of thyroid hormones, vitamins, and lipid peroxidation with the glycemic index in patients experiencing Type-2 diabetes. Some tests of biochemical parameters and vitamins were conducted on 35 patients experiencing Diabetes Mellitus (DM) and 35 healthy subjects. The results indicated the increase in the levels of MDA (3.86 ± 0.97 µmol/L), HbA1c (8.27 ± 1.66 %), FBS (198.34 ± 32.41 mg/dl) and TSH (5.67 ±0.34 mIU/L) in the blood of diabetic subjects in comparison to the controls at a P value lower than 0.05. These incr
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