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Effect of Some Demographic Changes on Some Oral Immune Aspects in Periodontal Disease Patients

Periodontal diseases (PD) are worldwide diseases of humans either in childhood or adults. The present study aimed to find the correlation between some demographic and saliva immunological factors including the determination of saliva TLR-2, IL6, CRP, and α- amylase in patients with periodontal diseases. For this purpose, 60 patients out of which 33were males and 27 were females participated in this study from different Dental treatment Centers (Amirya Specialized Dental Center and Almaamon Specialized Dental Center ) in Baghdad/ Iraq, for the period starting from November / 2021 to February / 2022. Both age ranges for patients and control are (13-70) years, and patients’ mean ages are 34.29±15.01. Additionally, the control specimens were collected randomly from 40 apparently healthy people. The results of some demographic parameters revealed that there were no significant differences between males 55.0% and females 45.0% in PD. As well as, periodontal disease is not directly associated with rising smoking among patients or non-smoking individuals with PD. Acidic oral pH is not significantly found in most PD patients 47.1% and control subjects 66.7%, simultaneously, smoking may not be associated with acidic oral saliva directly. Other tests in concern with PD patients are considered to be very important in many aspects, firstly interleukin (IL6) recorded high non-significant mean occurrence results in both patients’ 50161± 63869 ng/l and control 52087 ± 62756 ng/l groups. Secondly, C-reactive protein (CRP) as IL6, recorded a non-significant increase in the saliva of PD patients at 0.537 ± 0.607 mg/l and control at 0.607  ±  0.266 mg/l. Toll-like receptor-2 (TLR-2) is the third immune parameter measured in saliva which recorded significant differences between PD patients 7.384  ±  4.031 ng/ml and control 5.313  ±  3.106 ng/ml, simultaneously. Then the fourth saliva parameter is α-amylase the results recorded a significant difference between PD patients 2.444  ±  1.870 ng/ml and control 1.041  ±  1.044 ng/ml. Also, the results showed that there was no correlation between measured demographic and immunological parameters.

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Publication Date
Wed Apr 07 2021
Journal Name
Indian Journal Of Forensic Medicine & Toxicology,
Publication Date
Tue Jun 20 2023
Journal Name
Baghdad Science Journal
Estimation levels of CTHRC1and some cytokines in Iraqi patients with Rheumatoid Arthritis

Collagen triple helix repeat containing-1 (CTHRC1) is an essential marker for Rheumatoid Arthritis (RA), but its relationship with pro-inflammatory, anti-inflammatory, and inflammatory markers has been scantily covered in extant literature. To evaluate the level of CTHRC1 protein in the sera of 100 RA patients and 25 control and compare levels of tumour necrosis factor alpha (TNF-α), interleukin 10 (IL-10), RA disease activity (DAS28), and inflammatory factors. Higher significant serum levels of CTHRC1 (29.367 ng/ml), TNF-α (63.488 pg/ml), and IL-10 (67.1 pg/ml) were found in patient sera as compared to that in control sera (CTHRC1 = 15.732 ng/ml, TNF-α = 33.788 pg/ml, and IL-10 = 25.122 pg/ml). There was no significant correlation be

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Publication Date
Sun Apr 30 2023
Journal Name
Iraqi Journal Of Science
Determination the Relationship between Some genetic Aspects with the Capsule Formation for Pathogenic Klebsiella pneumoniae Serotypes K1 &K2

A total of 47 samples were collected from different clinical specimens (urine, wounds, burns, sputum, blood, stools) during the period from November 2013 to
January 2014, only 18 isolates (38.29%) were identified as Klebsiella pneumoniae ,11isolates (23.4%) as E. coli , 9 isolates (19.1%) as S. aureus, 3isolates (6.3%) as Psedomonase spp., 2 isolates (4.2 %) as K. terrigena and 4 isolates (8.5%) as K. oxytoca. The results were shown the elevation of K. pneumoniae percentage among the bacterial isolates depending on cultural, microscopically, biochemically characteristics and confirmed by using the API 20E and VITEK 2 system . Also K. pneumoniae isolates were more frequently in sputum samples then burns, stools , urine, wounds ,and blo

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Publication Date
Wed Oct 07 2020
Journal Name
Indian Journal Of Forensic Medicine & Toxicology
Effect of Insecticide “Maxxthor” on Some Hematological and Oxidative Stress Parameters in Male Albino Rats

The present study was designed to investigate the effect of different concentrations of Maxxthor on some hematological and oxidative stress parameters in male albino rats.Twenty male rats with age of 6-8 weeks and weight of 200-250gm were equally divided into four groups as follow:G1 treated with normal saline as control group,while G2,G3andG4groups were treated with(0.01,0.1,1)mg\kg body weight of Maxxthor respectively for 40 days.The following hematological parameters were measured: red blood cell(RBC),hemoglobin (Hb),white blood cell(WBC), platelets(PLT),malondialdehyde(MDA),glutathione(GSH),catalase and vitamin E. The hematological parameters results revealed highly significant(p<0.01)decreasein RBC and H,while a highly significant(p<0.

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Publication Date
Sun May 14 2017
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
Effect of GA3 on Growth and Some Physiological Characterizes in Carrot Plant (Daucus Carota L.)

             This experiment was carried out in the field of researches in Kalar Technical Institute / Field crop dept. The aim of the research is to study the effect of foliar sprays of different concentrations of Gibberellic acid on growth and some physiological characterizes in Carrot plant (local white cultivar). The experiment treatments included three concentrations of Gibberellic acid (0, 50 and 100 ppm) and were carried out as applicable agricultural project (3×4). And the results were recorded as follows:                           &n

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Publication Date
Mon Mar 08 2021
Journal Name
Baghdad Science Journal
the relationship btwen serum sialic and humoral immune response in patients with sthma

forty-six patients with asthma were tested for the scrum levels of total sialic and diffrental the results reveled a significant increased in the scra of asthmatic patients

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Publication Date
Tue Jul 01 2008
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Correlation between some immunological parameters and clinical presentation in RA patients

Background: Complement (C) & CRP in patients with Rheumatoid arthritis (RA)'could be trigger disease activity.
Aim: To study the correlation between C, CRP, IgM,, IgG, IgA & some clinical presentation in RA patients.
Methods: Latex agglutination test(AG) & single radial immunoassay(SRIA) were used to asses CRP, IgMJgGJgA,, C, in 74 patients with RA.
Results: IgA & IgG were significantly increased, while the mean ofC3, C4 were slightly elevated in RA patients .
Conclusion: There is correlation between IgG and IgM with joint deformity and joint swelling respectively, while C3 was showed statistically significant P<0.01 with joint
stiffness, joint swelling and Rheumatoid nodule, whe

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Publication Date
Wed Dec 14 2016
Journal Name
Journal Of Baghdad College Of Dentistry
Clinical and Sonographic Changes of Parotid Gland in Patients with Type I and Type II Diabetes Mellitus and Its Effect on Physical Properties of Saliva

Background: Sialosis described as a specific consequence of diabetes. In diabetic sialosis, the increased volume of the glands is due to the infiltration of adipose in the parenchyma. The B-scan ultrasonography is a generally accepted tool for determining parotid gland enlargement. Oral health is, to a greater extent, dependent on quality and quantity of saliva, both of which may be altered in diabetics. This study was established to detect the enlargement of parotid gland in diabetic patient and study the changes in physical properties of saliva and its relation with the salivary gland enlargement. Subjects, Materials and Methods: A cross-sectional study with highly specified criteria with ages ranged (20-65) years, male and female subject

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Publication Date
Sun Mar 01 2009
Journal Name
Baghdad Science Journal
Effect of leaves Extracts of Duranta repens on growth and activity of some types of Pathogenic Bacteria and Some types of Fungi

A study were conducted to examinate the effect of organic and aqueous (Hot, Cold) Extracts from leaves of Duranta repens on the growth and activities of the following types of Bacteria:- Staphylococcus aureus,Streptococcus pyogens ,Escherichia coli,Klebsilla pneumonia, in addition to the yeast Candida albicans and the fungi Aspergullis niger ,Aspergulls flavus.The result showed that gram Positive Bacteria is more sensitive to the extracts than gram negative bacteria with Minimum inhibitory concentration (MIC) value (50,25,50,100)% and Minimum Bactericidal Concentration (MBC) value (100,50,200,100)% for all types Bacteria respectively . The most active extract against A.niger ,A,flavus was cold and hot aqueous extract from the leaves with d

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Publication Date
Mon Jan 02 2012
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Disease modifying effects of simvastatin &/or telmisartan on pulmonary function in patients with mild to moderate chronic obstructive pulmonary disease(COPD)

Background: chronic obstructive pulmonary disease (COPD) is characterized by chronic airflow limitation and a range of pathological changes in the lung.

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