This study aimed to synthesize a novel amide prodrug of metformin with aspirin by amide bond. The structure was characterized by (FTIR, 1H-NMR, 13C-NMR and CHNO) ,Purification of the prepared compound was using column chromatography. Using of 40 rabbit having the same weight and devided into 4 groups (4x10) the first group (G1): (the control healthy group) was given drink water and didn’t give any material, second group(G2):( the control infected group) was given hydrogen peroxide concentration % 0.5 until infecting diabetes mellitus, third group(G3): was given hydrogen peroxide concentration as in (G2) and ( 250 mg/kg) of aspirin and (348.8 mg/kg) of metformin, fourth group(G4): was given hydrogen peroxide concentration as in (G2) and (596.3 mg/kg) of the proposed prodrug. After 3 hours, blood was taken from all groups, the serum was separated, and prepared to study it with biochemical and enzymatic study. Statistical data analysis revealed significant decrease in the levels of (lactate dehydrogenase, creatinkinase) , and significant decrease in the concentration of (Glucose) , and significant increase in the concentration of (total protein, albumin, globulin) affected by the prepared Compound [A] as compared with the control infected group. Statistical analysis revealed significant decrease in the levels of (Lactate dehydrogenase) and significant increase in the levels of (creatinkinase) , and significant increase in the concentration of (Glucose, albumin, total protein and globulin) affected by prepared compound [A] as compared with the control healthy group.
The research objective was to study the amount of lost fluids, some blood components and mineral salts in volleyball players under hot weather conditions. The sample of the present study was composed of 12 volleyball players of Al-Sinaa Club (Baghdad, Iraq) in the 2022/2023 season. The variables analyzed in this study were: Heart rate before and after exercise, internal and external body temperature before and after exertion, potassium ion, sodium ion, calcium ion, and the amount of fluid lost (the player's weight) before and after the exercise. The tests were conducted at a temperature between 42-47 degrees Celsius. The maximum anaerobic exercise was performed with volleyball. The results showed that to play volleybal
... Show MoreElection study included four sites for the waters in area of Youssifiyah south of Baghdad (river water, tank water, liquefactions water, and water filtrate and seethed and purifier by alum and chloride), the samples were collected during the month of June in 2007. Temperature, electrical conductivity and acidity are measured. Also , the concentration of chloride , sulphate , carbonate , nitrate , sodium , calcium , magnesium , hard total and total dissolved substances are determined , as well as heavy metals assess environmental risk (such as Cu, Pb, Zn, Fe). It was also a study of bacterial totals included both total Bacteria (TB) and Total Coliform Bacteria (TC) and Fecal Coliform (FC) and Fecal Streptococci (FS). The stu
... Show MoreHuman cytomegalovirus (CMV) infection is associated with higher risk of cardiovascular diseases in immunocompromised organ transplant patients; it has been linked with the elevated arterial blood pressure. This study aimed to find a relationship between CMV antibody titers and blood pressure elevation by using the enzyme-linked immunosorbent assay (ELISA) to measure CMV IgG levels in the serum of 60 patients with high blood pressure, in comparison to 30 healthy persons with normal blood pressure as a control. All patients and control were 25-50 years old. The results showed that CMV antibody titers were higher in those who undergo blood pressure elevation. This finding supports the hypothesis that; the common CMV infection may leads to i
... Show MoreBackground: Coronavirus, which causes respiratory illness, has been a public health issue in recent decades. Because the clinical symptoms of infection are not always specific, it is difficult to expose all suspects to qualitative testing in order to confirm or rule out infection as a test. Methods: According to the scientific studies and investigations, seventy-three results of scientific articles and research were obtained using PubMed, Medline, Research gate and Google Scholar. The research keywords used were COVID-19, coronavirus, blood parameters, and saliva. Results: This review provides a report on the changes in the blood and saliva tests of those who are infected with the COVID-19.COVID-19 is a systemic infection that has
... Show MoreThe D.C electrical and thermoelectrically properties of randomly mixed isolator – electrolyte system as (Al/ PVC – LiF/Al) junction consisting of polyvinyl chloride (PVC)resin reinforced with Lithium Fluoride (LiF) powder were studied. A comparison is made the properties of (PVC) material with varying percentage of (LiF) powder (0%, 30%, 50%, 80%)to find out the effect of reinforcement of isolator material. The composites dissolving in 10ml form tettraHaedroflourn (THF) and Solution were the castled in Petri dish and Laved it dry in the air, The out coming Sample were disc - Like shape of a diameter of about 3cm and thickness reneged between (0.01- 0.018) cm . The composites dissolving in 10ml form tettraHaedroflourn (THF) a
... Show MorePeriodontal diseases (PD) are worldwide diseases of humans either in childhood or adults. The present study aimed to find the correlation between some demographic and saliva immunological factors including the determination of saliva TLR-2, IL6, CRP, and α- amylase in patients with periodontal diseases. For this purpose, 60 patients out of which 33were males and 27 were females participated in this study from different Dental treatment Centers (Amirya Specialized Dental Center and Almaamon Specialized Dental Center ) in Baghdad/ Iraq, for the period starting from November / 2021 to February / 2022. Both age ranges for patients and control are (13-70) years, and patients’ mean ages are 34.29±15.01. Additionally, the c
... Show MoreAloin extracted into alcohol-rich phase with high extraction efficiency,
meanwhile majority polysaccharides, proteins, mineral substances and other
impurities were extracted into salt-rich phase. Partitioning of AQs[Anthraquinones]
is dependent on hydrophobic interaction, hydrogen bond interaction, and salting-out
effect in Aqueous tow –phase system [ATPS]. Aloin was partially purified by using
1-propanol [NH4] 2SO4, the use of this solvent showed high efficiency 90.61%
compared with other solvent [2-propanol and ethanol]. The concentration of aloin
detected by HPLC technique, which reached to 91.84% as focus turns out that there
is compatibility between the sample and the standard in shape and retention time
Typhoid fever (TF) is a systemic infection caused by Salmonella Typhi (Salmonella Enterica) transmitted through contaminated water, food, or contact with infected individuals. In various infectious diseases, blood viscosity (BV) is affected by changes in hemoglobin concentrations and acute phase reactants. Inflammatory responses can lead to elevated plasma protein levels and further affect BV. This study aimed to investigate BV changes in patients with acute TF. A cross-sectional study was performed involving 55 patients with acute TF compared to 38 healthy controls. BV and inflammatory parameters were measured in both groups. TF patients showed reduced blood cells compared to healthy controls (p=0.001). Additionally, plasma total protein (
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