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jih-2271
Automated Reconstruction and Manual Curation of Amino Acid Biosynthesis Pathways in Sulfolobus solfataricus P2
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The efficient sequencing techniques have significantly increased the number of genomes that are now available, including the Crenarchaeon Sulfolobus solfataricus P2 genome. The genome-scale metabolic pathways in Sulfolobus solfataricus P2 were predicted by implementing the “Pathway Tools” software using MetaCyc database as reference knowledge base. A Pathway/Genome Data Base (PGDB) specific for Sulfolobus solfataricus P2 was created. A curation approach was carried out regarding all the amino acids biosynthetic pathways. Experimental literatures as well as homology-, orthology- and context-based protein function prediction methods were followed for the curation process. The “PathoLogic” component of the “Pathway Tools” programme was able to predict many amino acid biosynthetic metabolic pathways. The total number of the metabolic pathways was modified to 168 pathways by adding extra pathways that have not been detected by the “PathoLogic”. Amino acid biosynthetic pathways such as alpha-aminoadipic acid (AAA) pathway of Lysine biosynthesis and Alanine biosynthesis as well as the super-pathway of Phenylalanine, Tyrosine and Tryptophan biosynthesis variation II were added to the Pathway/Genome data base of Sulfolobus solfataricus P2. Discovery of the missing enzymes that have to fill in the metabolic holes in the pathways under study was the main curation task. This approach and the curated amino acid biosynthetic pathways in the PGDB of Sulfolobus solfataricus P2 can be used for genomic annotations and metabolic pathway reconstructions of closely related Bacteria and Archaea.

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Publication Date
Wed Oct 07 2020
Journal Name
Indian Journal Of Forensic Medicine & Toxicology
Biological Activity of Complexes of Some Amino Acid: Review
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Publication Date
Thu Sep 13 2012
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
Density and Viscosity of Amino Acid Serine in aqueous dimethyl sulfoxide solution at deferent temperatures
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Publication Date
Sun Jul 02 2006
Journal Name
Journal Of The Faculty Of Medicine Baghdad
activation of complements pathways in patients with bachcet's disease
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Background:

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Publication Date
Sat Jan 11 2025
Journal Name
Al–bahith Al–a'alami
Qualitative Researches in Media and Communication Sciences: Theoretical Highlights and Applied Pathways
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The debate on the methodology of media and communication research is no longer subject to the logic of the contradiction between the quantitative and the qualitative approach, nor the logic of the comparison between them. The nature of the topics presented for research, the problems they raise, the goals to be achieved from the research, and the epistemological positioning of researchers are among the critical factors that dictate the appropriate approach or methodological approaches to conduct their research. This positioning means the implicit philosophical principles upon which any researcher relies and which determine the path he/ she takes to produce scientifically approved knowledge. The method of the researcher's access to the phe

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Publication Date
Mon Sep 03 2018
Journal Name
Al-academy
Typographic Accomplishment between the Manual Skill and Contemporary Technology
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     The typographic accomplishment is the most important means of cognitive communication and carries a message from the sender to the recipient which serves a certain objective functionally, economically and advertisingly.

            The design of typographic accomplishment depends on two different techniques, the first is manual, which depends on the skill, training and individual achievement of the designer and his ability to design and produce typographic accomplishment with manual skill effects. The second one is the contemporary digitization which is represented by computers, programs and printers attached to them. The problem of the current resear

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Publication Date
Wed Apr 26 2017
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
Synthesis and Antibactrial Study of New 2-Amino-5-Aryl- 1,3-Thiazole-4-Carboxylic Acid Derivatives
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2-Amino-5-aryl- 1,3-thiazole-4-carboxylic acid (A1-A3) were synthesized from the reaction of various aromatic aldehyde with dichloro acetic acid and thiourea. The synthesis of 2-[[(Saminosulfinim-idoyl)(aryl)methyl](benzoyl)amino]-5-aryl-1,3-thiazole-4-carboxylic acid (A22-A30) was perfomed starting from (A1-A3) by two steps using Schiff's base (A4-A12) prepared  from the reactant compounds (A1-A3) with different aromatic aldehyde. Finally two types of imide derivatives were obtained from reactant compounds (A1-A3) with malic anhydride (A31-A33) and phthalic anhydride (A34-A36) in the presence of glacial acetic acid. All proposed structures were supported by FT-IR and UV-Visible spectroscopic data.  
 

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Publication Date
Sun Dec 25 2022
Journal Name
International Journal Of Drug Delivery Technology
Effect of Zinc drug on amino acid concentration in liver of white mice, Mus musculus
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Zinc is one of the essential trace elements, it plays a key role in many biochemical and functional processes. It is less harmful than many other minerals, in the case of exposure to high doses of zinc, poisoning occurs, and this poisoning may mostly result from the accidental ingestion of household products containing zinc or nutritional supplements, this study was conducted to find out the effects of zinc on the concentration of amino acid. A total of 30 adult white mouse males were taken and divided into three groups; the first group (control) of 10 mice taken with distilled water for 30 days, the second group includes 10 mice that were dose with Zn drug concentration of 50 mg/kg/day for 30 days, the third group includes 10 mice that wer

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Publication Date
Sun Dec 04 2016
Journal Name
Baghdad Science Journal
Synthesis and Characterization of some New 1,3,4-Oxadiazole derivatives based on 4-amino benzoic acid
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Various of 2,5- disubstituted 1,3,4-oxadiazole (Schiff base, ?- lactam and azo) were synthesized from 2,5-di (4,4?-amino-1,3,4-oxadiazole which usequently synth-esized from mixture of 4- amino benzoic acid and hydrazine arch of polyphosphorus acid. The synthesized compounds were cherecterized by using some spectral data (UV, FT-IR , and 1H-NMR)

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Publication Date
Thu Mar 30 2023
Journal Name
Iraqi Journal Of Science
Evaluation of Antioxidant Activity of Acoholic Extracts from Pleurotus ostreatus (P2) In Vivo
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In this study found treatment mice exposed to CCl4 with the alcoholic extract of Pleurotus ostreatus (P2) at (25) mg/ml appeared to exert a beneficial effect since the activities of catalase, was significantly (p<0.05) higher in liver treatment with alcoholic extract of P. ostreatus (P2) (37.290+2.638) μmol/mg than in aqueous extract for the same fungus (36.557+2.231) μmol/mg. Super oxide dismutase (SOD) was significantly (p<0.05) higher in liver treatment with alcoholic extract of P. ostreatus (P2) at (25) mg/ml (17.863+0.454)U/mg than in aqueous extract (17.863+0.454) U/mg for the same fungus and same concentration. Glutathione peroxidase (Gpx) was significantly (p<0.05) higher in liver treatment with alcoholic extract of P.

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Publication Date
Wed Mar 29 2017
Journal Name
Iraqi Journal Of Pharmaceutical Sciences ( P-issn 1683 - 3597 E-issn 2521 - 3512)
Validity of Generalized Standard Addition Method for a Mixture of Amino Acid Analysis
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A Modified version of the Generlized standard addition method ( GSAM) was developed. This modified version was used for the quantitative determination of arginine   (Arg) and glycine ( Gly) in arginine  acetyl salicylate – glycine complex . According to this method two linear equations were solved to obtain the amounts of (Arg) and (Gly). The first equation was obtained by spectrophotometic measurement of the total absorbance of (Arg) and (Gly) colored complex with ninhydrin . The second equation was obtained by measuring the total acid consumed by total amino groups of (Arg) and ( Gly). The titration was carried out in non- aqueous media using perchloric acid in glacial acetic acid as a titrant. The developed metho

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