Preferred Language
Articles
/
jih-2011
Comparison Study of the Effect of Erlotinib as a Tyrosine Kinase Inhibitor on Electrolyte Levels in Type2 Diabetic and Diabetic Nephropathy

Diabetes mellitus can be defined as  a metabolic disorder disease .Complication  of diabetes  are due to diabetic nephropathy .This study was done in vitro to study the effect of different concentrations of erlotinib inhibitor ( tyrosine kinase inhibitor) on electrolyte levels (Mg⁺²,Ca⁺²,Na⁺) in sera of Iraqi patients with  newly diagnosis type2 diabetes and diabetic nephropathy in addition to find the best percentage inhibition for utilizing different concentrations from erlotinib (6.97x10⁻⁷, 9.30x10⁻⁷ ,1.16x10⁻⁶,1.39x10⁻⁶ ,1.62x10⁻⁵ )molar  on electrolyte levels . This study was conducted in The National Diabetes Center, Al-Mustansiriya University - Baghdad and included 150 patients divided into50 patients type 2 diabetic as group (G2) , 50patients diabetic nephropathy as group(G3) and also 50 healthy as control group(G1).The period time for aggregation the blood sampling  was from July to October 2017 . All patients were within (18 to 60) years age. Erlotinib(Tyrosine kinase  inhibitor) affected  on serum Mg ⁺²levels in human as a mild effect and a slight effect on seum Na⁺ and Ca⁺².The best inhibition of erlotinib in concentration (1.62x10⁻5)M for both  serum Na⁺ and Ca⁺² in newly diagnosis diabetes type 2 and diabetic nephropathy.serum  Mg ⁺²levels showed best inhibition in  concentration (9.30x10⁻7)M

Crossref
View Publication Preview PDF
Quick Preview PDF
Publication Date
Wed Jan 02 2013
Journal Name
Journal Of The Faculty Of Medicine Baghdad
prevalence of Metabolic Syndrome in Type 2 Diabetic Patients in Baghdad Teaching Hospital

Summary: Background: There is an epidemic of several non communicable diseases and metabolic abnormalities in humans including hypertension, obesity, hyperlipidemia, low high density lipoprotein cholesterol, microalbuminurea, and insulin resistance. These diseases and metabolic abnormalities have been collectively classified as metabolic syndrome and are closely associated with type 2 diabetes and other health problems including death. objectives: To investigate the prevalence of metabolic syndrome among type 2 diabetic patients in Baghdad teaching hospital,the frequency, and distribution of risk factor

... Show More
Crossref
View Publication Preview PDF
Publication Date
Sat Aug 31 2019
Journal Name
Iraqi Journal Of Physics
Investigate Salts type and concentration on the conductivity of Polymer Electrolyte

Polymer electrolytes systems compose of (PEO+KI+I2) and (PEO+RbI+I2) with different concentration, and a fixed amount of ethylene carbonate (EC) and propylene carbonate (PC) over temperatures range 293-343 K prepared by solution cast me

... Show More
Crossref (3)
Crossref
View Publication Preview PDF
Publication Date
Mon Oct 17 2022
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Evaluation of the Role of Serum Malondialdehyde in the Pathogenesis of Diabetic Retinopathy

Background:  The most typical consequence of diabetes mellitus is diabetic retinopathy. An important part of the etiology of diabetes and diabetic retinopathy is played by oxidative stress. Malondialdehyde is a dialdehyde that is moderately toxic and is frequently used as a marker for oxidative stress as well as lipid peroxidation.                    

Objectives: To assess the serum malondialdehyde levels in diabetic patients with and those without retinopathy and to compare these levels to controls .In additions to, investigate the relationship between serum malondialdehyde level and long glycemic control, the glycated hemoglobin (HbA1c).

Pati

... Show More
Crossref
View Publication Preview PDF
Publication Date
Thu Jan 02 2014
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Microalbuminuria in children and adolescent with type 1 Diabetes mellitus attending the diabetic center of children welfare teaching hospital.

Backgrounds: Despite advances in management of diabetes mellitus, it remains one of the major causes of morbidity and mortality, yet diabetic nephropathy is one of the main complications of diabetes mellitus. .Microalbuminuria is the beginning to the renal complications of diabetes mellitus; it is a significant index of early detection as well as monitoring the progression of diabetic nephropathy.                                                       

... Show More
Crossref (1)
Crossref
View Publication Preview PDF
Publication Date
Sun Apr 02 2006
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Crossref
View Publication Preview PDF
Publication Date
Wed May 11 2011
Journal Name
Tikrit Journal Of Pure Science
Isolation and partial purification malatase isoenzymes from urine of type 2 diabetic patients

This study was performd on 50 urine specimens of patients with type 2 diabetes, in addition, 50 normal specimens were investigated as control group. The activity rate of maltase in patients (6.40±2.17) I.U/ml and activity rate of maltase in normal (0.44±0.20)I.U/ml. The results of the study reveal that maltase activity of type 2 diabetes patient's urine shows significant increase (P<0.01) compare to normal.

Publication Date
Sun Jan 30 2022
Journal Name
Iraqi Journal Of Science
The Effects of Zinc and Vitamin C Supplementation on the Glycemic Profile in Type 2 Diabetic Patients

     Diabetes mellitus (DM) is the most common endocrine disorder and one of the highly progressive diseases which is indicated by high blood sugar (hyperglycemia). The present study aims to study the effects of treatment with zinc and vitamin C on glycemic profile [fasting blood sugar (FBS), glycated haemoglobin (HbA1C), and insulin hormone level] in type 2 diabetic patients. The study included 56 diabetic patients [30 without foot ulcers (15 without zinc and vitamin C supplements, 15 with zinc and vitamin C supplements) and 26 with foot ulcers (15 without zinc and vitamin C supplements, 11 with zinc and vitamin C supplements)]. Also, 15 healthy persons were used as a control group. The patients were enrol

... Show More
Scopus (4)
Crossref (2)
Scopus Crossref
View Publication Preview PDF
Publication Date
Tue Mar 30 2021
Journal Name
Iraqi Journal Of Science
Indications of Liver and Kidney Functions in Non-Insulin Dependent Diabetic Patients

This study aimed at the investigation of abnormal liver and renal functions by biochemical manifestations of underlying metabolic abnormalities in relation to hyperglycemia in non-insulin-dependent diabetic patients. The study comprised 118 diabetic patients (56 males, 62 females) and 60 age-matched healthy non-diabetic controls (30 males, 30 females). All subjects were tested for serum levels of liver enzymatic indicators, which include aspartate transaminase (AST), alanine transaminase (ALT), and alkaline phosphatase (ALP), as well as non enzymatic parameters, including total bilirubin and total proteins.Also, serum levels of renal function markers, including microalbumin, creatinine, urea, and uric acid were measured.

The find

... Show More
Scopus (3)
Crossref (1)
Scopus Crossref
View Publication Preview PDF
Publication Date
Sun Dec 01 2013
Journal Name
The Iraqi Postgraduate Medical Journal
Comparative Study Between Glimepiride and Glibenclamide in the Treatment of Type 2 Diabetic Patients in Al-Yarmouk Hospital

Comparative Study Between Glimepiride and Glibenclamide in the Treatment of Type 2 Diabetic Patients in Al-Yarmouk Hospital

View Publication
Publication Date
Fri Jun 30 2006
Journal Name
Al-kindy College Medical Journal
Oral Carriage Rate of Candida Species in Diabetic Patients

Background: It is well known that oral carriage
of Candida species increase in many situations, like
obesity, debility, leukemia, viral infection, use of
certain drugs in addition to diabetes mellitus.
Objective: find the relation between diabetes and
its control on oral carriage of Candida.
Methods: Thirty four hundred oral swabs from
diabetic patients 67% are females and 33% are
males, 41.7% are type 1 diabetes and 58.3% are type
2.different culture media are used.
Results: we found that 37.9% of diabetics had oral
carriage, older age group had more but the
difference is not significant statistically P>0.05, in
addition females carry more Candida than males
P<0.05, while type of diabetes

... Show More
View Publication Preview PDF