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Background and Objectives: Wound healing is a complex process with overlapping phases
haemostasis, inflammation, proliferation and maturation/matrix remodeling. Each phase of
wound healing requires different management strategies, and inappropriate treatment can delay
wound healing. The aim of the present study was to evaluate the efficacy of topical application
of calmodulin as a significant augmentation of the granulation tissue production process of
wound healing and to express of genes CaMKK2, MaP2K6 and CXCR4 at site of wound
defect, that have versatile effects on the body and they belong to Ca/camodulin related genes.
Material and Methods: In this study thirty albino male rats, weighting (300-400) gram, aged
(6-8) months, wil
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