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jih-1660
A New Biological System For Detecting Environmetal Carcinogens And /Or Mutagenes And Their Adversary
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A  new  test  system  for  detecting  environment  carcinogenes and/or  mutagenes  and  their  adversary  It  has  been  induced.  One hundred and fifty   mutants   were isolated from   the basidiomycete fungus Coprinus cinereus   which were   resistant to guanine analogue S- az.aguanine .All the spontaneous and induced with UV light origin mutants were isolated from the wild type strains Bc9/6.6 and  Hd5.5

.These mutants were te ted on selective medium containing  different

concentrations of the analogue and also to their ability to usc purine bases and their degredated  products as  a sole  nitrogene source were tested ; and their ability to grow on HAT   medium was tested . According  to  the results obtained  from these test;  mutants  were

classified into four phenotypic groups for each  iJd -type strain .

All  the  8-az.aguanine  resistant  mutants  were  d.ikaryotized   with

compatible wild strains. The dikaryons produced were unable to grow on  medium           containing        8-az.aguanine                     which               establish the recessiveness of the mutations to their respective wi ld-type alleles. Complementation   test  detcrmind  four  genes   which  controll   the resi stance  to 8- azaguaninc in Coprinus cincres   .These genes were desi gnated  azg-1, azg-2, azg'-3, azg-4.Three of these genes azg-1, azg-2 and azg'-4werc carried by Bc9/6.6 and Hl /5.5 mutants. While, azg-3 gene  was found in Bc9/6.6 mutants only.

These  genes  are determ.ind for  the  first  time  in  fungus coprinus cinereus  .

Mutants which carry azg-1  gene were characterized by their inability to use   hypozanthine and                                              guanine as a sole nitrogen source in the

medium ; their failure to grow  on HAT medium  and their resistance

to all concentrations of 8- az.aguanine used.This gene is considered to

 

 

 

 

IBN AL- HAITHAM J.FOH PURE & API'L.SCI.         VOL.19(4) 2006

 

represent  a mutation led to   lose or   modify the specificity of the enzyme hypoxauthine -guanine phosphoribosyl transferase (HGPRT) whi ch play an important role in transferring hypoxauthine and guanine to their nucleotides  by salvage pathway.

Spore analysis indi cated that azg'-1  gene locted in linkage group II

,since it gave a distance of 28 map units with the mating type gene

B.

The assessment of the cytotoxic , mutagn ic and antimutagc•tic role of

the  aqueous extract of  garl ic     (Allium  sativum  L.)  against the genotoxic effect of mitomycin - C

( MMC ) evaluate the ability of the mutagen to induce mutation in

HGPRT gene by    using the asexual spores (oidia )of Copninus cineraus for the strain AZG78 and by depending on the viabil ity and mutation rate in HGPRT gene test .To assess cytotoxity and mutagenecity of garlic extract , gradual concentrations were prepared . The concentration of choice was considered with respect to  two factors ; high survi val rate and low mutagenic  activity (similar to negative control ). To examine the antimutagenic  effects of  the extract, an interation was made between the crude  extract and the mutagen   MMC with respect to three kinds of treatments before , aOer and with mutagen . The study concentrated on two sides 1- on the toxic and /or m utagenic effect of the aqueous extract of garlic . 2 - Antimutagenic activity of the extract with respect to   the mutageen MMC . However,   this activity was dependent on the type of the treatment . The extract showed best antimutagenic activity when it was used before the mutagen , so itis considered as desmutagen to the genotox i c effects of MMC.

These data support the hypothesis that garlic compounds may be eflicacius in preventions of cancer and also we could use the HGPRT

gene as  a  sensitive biological  system  in  detecting environmental mutagenes or carcinogens and their adversary .

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Publication Date
Thu Dec 09 2021
Journal Name
Iraqi Journal Of Pharmaceutical Sciences ( P-issn 1683 - 3597 E-issn 2521 - 3512)
Cressa cretica Pharmacognosy, and Pharmacology (A review )
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Cressa cretica (Shuwwayl) is a halophytic that belongs to Convolvulaceae, naturally grown in the Middle East including Iraq. Traditionally the plant is used as a paste for sore treatment, also it is used for fever, jaundice, and other illness. Regarding nonclinical use it is used as goat, sheep, and camel feed also as an oil source. Flavonoids including quercetin, kamepferol, apigenin, and their glycosides, phenolic acid as chlorogenic acid, and phytosterols mainly ?–sitosterol were the most important phytochemicals that were detected in this halophyte. Crude ethanolic, methanolic extracts and ethyl acetate fraction of the areal parts were used in clinical studies and demonstrated various effe

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Publication Date
Thu Sep 13 2018
Journal Name
Baghdad Science Journal
Design and Evaluation of a Polarizer Filter
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This research includes theoretical and evaluation design of a polarizer filter of high transmission in the near IR region of (900-1200nm) for different incidence angles to obtain a long wave and short wave pass filter using analytical calculations. Results refer to a new configuration design in fewer layers than used in previous studies in the long wave pass at incidence angles (45o,50o,55o). Adopted Hafnium dioxide (HfO2) and Magnesium fluoride (MgF2) as coating material at design wavelength (933nm), the study also included design short wave pass polarizer by using the same coating material.

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Publication Date
Wed Sep 12 2012
Journal Name
Journal Of Engineering
Design and Implementation of a Vlsm Simulator
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Variable-Length Subnet Masks (VLSM), often referred to as "subnetting a subnet", is used to maximize addressing efficiency. The network administrator is able to use a long mask on networks with few hosts, and a short mask on subnets with many hosts. This addressing scheme allows growth and does not involve wasting addresses. VLSM gives a way of subnetting a network with minimal loses of IP addresses for a specific range. Unfortunately, the network administrator has to perform several mathematical steps (or use charts) to get the required results from VLSM. In this paper, a simple graph simulator is proposed (using Visual Basic 6.0 Language) to perform all the required mathematical steps and to display the obtained required information (the

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Publication Date
Fri Oct 02 2020
Journal Name
Biochemical & Cellular Archives
Retinoids and rexinoids as vitamin A analogs.
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Vitamin A, namely retinol is still the most proper agent for modulating so many biochemical reactions and biological functions in different tissues and organs. In addition to the provitamins A and α, βand γ-carotenoids that are present in various foods from either animal or plant origin, retinoids and rexinoids form the natural and synthetic analogs that are chemically related or unrelated and can be added as food supplements for deficiency disorders of vitamin A or used to alleviate or treat certain health problems such as skin carcinoma, acne, skin aging and dermatitis.

Publication Date
Tue Aug 02 2022
Journal Name
Journal Of Legal Sciences
Jurisprudence and its controls - A Comparative study
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Judicial jurisprudence is one of the important legal solutions to address the shortcomings of legislation. Throughout its long history, human societies have known many cases in which the judge finds himself facing a legislative vacuum in addition to civil legal texts that are difficult for the judge to implement due to ambiguity or contradiction, which requires diligence. To rule on resolving disputes before him in order not to deny justice, but the judge in his jurisprudence was not absolute, but rather bound by certain controls represented by observing the wisdom of legislation on the one hand and taking into account the nature of the texts on the other side, and from here this research came to shed light on the jurisprudence and its cont

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Publication Date
Wed Jan 01 2014
Journal Name
Journal Of The College Of Languages (jcl)
A comparison between Objective and subjective tests
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This paper aims at presenting a comparison between objective and subjective tests . This paper attemptsto shed light on these two aspects of tests and make do a compression by using suitable techniques for objective and subjective tests .

     The paper compares between the two techniques used by the objective and subjective tests respectively, the time and efforts required by each type, the extent to which each type can be reliable, and the skills each type is suitable to measure.

     The paper shows that objective tests, on the contrary of the subjective ones, encourages guess> Objective tests are used to test specific areas of langua

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Publication Date
Thu Jun 15 2023
Journal Name
Journal Of Baghdad College Of Dentistry
Molar tubes and failure rates–A review
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Objectives: To review the failure rates of molar tubes and the effect of molar tube base design, adhesive type, and bonding technique on the failure rates of molar tubes. Data: The revolution of molar bonding greatly impacted fixed orthodontic appliance treatment by reducing chair-side time and improving patient comfort. Even with the many advantages of molar bonding, clinicians sometimes hesitate to use molar tubes due to their failure rates. Sources: Internet sources, such as Pubmed and Google Scholar. Study selection: studies testing the bond failure rate of molar tubes. Conclusions: The failure rate of the molar tubes can be reduced and the bond strength of the molar tubes can be improved by changing the design of the molar tube base

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Publication Date
Mon Apr 20 2020
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
A Review: Saccharin Discovery, Synthesis, and Applications
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    Saccharin is firstly synthesized in 1879. It is a very well-known as an inexpensive substitute for sugar as it is a non-caloric sweetener. The article shows the properties, use, metabolism and various synthesis and reactions of saccharine. Moreover, the toxicological reports explain that saccharin is mostly responsible for the bladder tumors observed in the male rats, the relationship between the consumption of saccharin and bladder cancer is afforded by epidemiological studies.  The benefit-risk evaluation for saccharin is hardly to indicate. Saccharin is a sugar substitute, frequently used either in food industry, or in pharmaceutical formulations and even in tobacco products. The chemistry of saccharin is inter

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Publication Date
Mon Jul 01 2019
Journal Name
Journal Of Educational And Psychological Researches
Constructing a Scale for the Nine Types of Students Personality: Constructing a Scale for the Nine Types of Students Personality
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Abstract

The current research aims to construct a scale for the nine types of students’ personality according to Rob Fitzel model. To do this, (162) items were formed that present the nine types of personality with (18) items for each type. To test the validity of the scale, a sample of (584) students of Al-Mustansrya University were chosen. The data of their responses was analyzed by using factor analysis. The findings explored (9) factors as one factor for each type of personality with (12) items for each one. Then, the reliability of the scale was found by using the test-retest method and Alfa Cronbach method.

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Publication Date
Wed Dec 04 2024
Journal Name
المورد
((The effect of mentioning, deleting, or changing the form of some Arabic letters on the meaning of the context of the sentence in Arabic))
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The letters are exposed in some texts of the classical Arabic language (poetry or prose), or in some of the Qur’anic texts, which are the main sources that were adopted on the day when provisions, rules and linguistic controls were established. I say that some of these letters are exposed in some contexts to deletion, mention, or change in the structure and shape of the letter. As for the omission, it is one of the aspects that distinguished Arabic, as well as other languages, for many purposes that differ among their user.

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