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A New Biological System For Detecting Environmetal Carcinogens And /Or Mutagenes And Their Adversary
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A  new  test  system  for  detecting  environment  carcinogenes and/or  mutagenes  and  their  adversary  It  has  been  induced.  One hundred and fifty   mutants   were isolated from   the basidiomycete fungus Coprinus cinereus   which were   resistant to guanine analogue S- az.aguanine .All the spontaneous and induced with UV light origin mutants were isolated from the wild type strains Bc9/6.6 and  Hd5.5

.These mutants were te ted on selective medium containing  different

concentrations of the analogue and also to their ability to usc purine bases and their degredated  products as  a sole  nitrogene source were tested ; and their ability to grow on HAT   medium was tested . According  to  the results obtained  from these test;  mutants  were

classified into four phenotypic groups for each  iJd -type strain .

All  the  8-az.aguanine  resistant  mutants  were  d.ikaryotized   with

compatible wild strains. The dikaryons produced were unable to grow on  medium           containing        8-az.aguanine                     which               establish the recessiveness of the mutations to their respective wi ld-type alleles. Complementation   test  detcrmind  four  genes   which  controll   the resi stance  to 8- azaguaninc in Coprinus cincres   .These genes were desi gnated  azg-1, azg-2, azg'-3, azg-4.Three of these genes azg-1, azg-2 and azg'-4werc carried by Bc9/6.6 and Hl /5.5 mutants. While, azg-3 gene  was found in Bc9/6.6 mutants only.

These  genes  are determ.ind for  the  first  time  in  fungus coprinus cinereus  .

Mutants which carry azg-1  gene were characterized by their inability to use   hypozanthine and                                              guanine as a sole nitrogen source in the

medium ; their failure to grow  on HAT medium  and their resistance

to all concentrations of 8- az.aguanine used.This gene is considered to

 

 

 

 

IBN AL- HAITHAM J.FOH PURE & API'L.SCI.         VOL.19(4) 2006

 

represent  a mutation led to   lose or   modify the specificity of the enzyme hypoxauthine -guanine phosphoribosyl transferase (HGPRT) whi ch play an important role in transferring hypoxauthine and guanine to their nucleotides  by salvage pathway.

Spore analysis indi cated that azg'-1  gene locted in linkage group II

,since it gave a distance of 28 map units with the mating type gene

B.

The assessment of the cytotoxic , mutagn ic and antimutagc•tic role of

the  aqueous extract of  garl ic     (Allium  sativum  L.)  against the genotoxic effect of mitomycin - C

( MMC ) evaluate the ability of the mutagen to induce mutation in

HGPRT gene by    using the asexual spores (oidia )of Copninus cineraus for the strain AZG78 and by depending on the viabil ity and mutation rate in HGPRT gene test .To assess cytotoxity and mutagenecity of garlic extract , gradual concentrations were prepared . The concentration of choice was considered with respect to  two factors ; high survi val rate and low mutagenic  activity (similar to negative control ). To examine the antimutagenic  effects of  the extract, an interation was made between the crude  extract and the mutagen   MMC with respect to three kinds of treatments before , aOer and with mutagen . The study concentrated on two sides 1- on the toxic and /or m utagenic effect of the aqueous extract of garlic . 2 - Antimutagenic activity of the extract with respect to   the mutageen MMC . However,   this activity was dependent on the type of the treatment . The extract showed best antimutagenic activity when it was used before the mutagen , so itis considered as desmutagen to the genotox i c effects of MMC.

These data support the hypothesis that garlic compounds may be eflicacius in preventions of cancer and also we could use the HGPRT

gene as  a  sensitive biological  system  in  detecting environmental mutagenes or carcinogens and their adversary .

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Publication Date
Tue Dec 31 2019
Journal Name
Journal Of Economics And Administrative Sciences
The Role of Information Technology Competency in Activating of Human Resources Management Practices/ Applied Study in the Informatics and Communications Public Company in Iraq
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This research aims to clarify the role of Information Technology Competency (ITC) with dimensions' (IT Usage, IT Knowledge, and IT Operations) as an independent variable in the activation of Human Resources Management Practices (HRM Practices) as a dependent variable with dimensions' (Training and Development, Recruitment, Job Design, and Performance appraisal). Based on this, the correlation and effect relationships between the independent and dependent variables are determined by formulating two main hypotheses. There are a significant relationship and effect of IT competency with HRM practices within the dimensions. Furthermore, the scope and population of this research are the Informatics and Communications P

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Publication Date
Mon Mar 25 2019
Journal Name
Al-academy
The Aesthetic Discourse of the Pop Artists and its Representations in the Output of Students of the Department of Art Education: هند عبدالله عبد
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The emergence of artistic movements in Western countries was after the period of modernity. They have introduced a great dialectical problem at the level of thought and discourse, which necessitated a change in the course of the aesthetic discourse into new visions. Thus, the present research aims to identify the aesthetic discourse of pop artists' Art and its representations in the outputs of the students of the Department of Art Education. The theoretical framework included two sections: the first one, what is the aesthetic discourse and the second is the educational bases of the students' outputs. The procedures of the current research included the analytical descriptive approach. The research sample consisted of (4) outputs chosen ac

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Publication Date
Sun Jun 01 2014
Journal Name
Baghdad Science Journal
The construction of Complete (kn,n)-arcs in The Projective Plane PG(2,5) by Geometric Method, with the Related Blocking Sets and Projective Codes
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A (k,n)-arc is a set of k points of PG(2,q) for some n, but not n + 1 of them, are collinear. A (k,n)-arc is complete if it is not contained in a (k + 1,n)-arc. In this paper we construct complete (kn,n)-arcs in PG(2,5), n = 2,3,4,5, by geometric method, with the related blocking sets and projective codes.

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Publication Date
Fri Sep 15 2017
Journal Name
Journal Of Baghdad College Of Dentistry
The Effect of Enamel Protective Agent on Shear and Tensile Bond Strength of Stainless Steel Brackets by Using Different Adhesive Agents (In Vitro Study)
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Background: Decalcification of surface enamel adjacent to fixed orthodontic appliances, in the form of white spot lesions, is a wide spread and familiar well-known side effect of orthodontic treatment. The present study was carried out to evaluate the effect of enamel protective agent (Clinpro white varnish) on shear and tensile bond strength of Dentaurum orthodontic stainless steel brackets by using 3M Unitek and Ormco as orthodontic adhesive agents. Materials and methods: Sixty-four extracted human upper first premolar teeth were selected and randomly divided into two groups with 32 teeth each, representing the shear and tensile bond strength testing groups. Then according to the type of bonding adhesive and the addition of Clinpro before

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Publication Date
Tue Jan 24 2023
Journal Name
Journal Of Advanced Biotechnology And Experimental Therapeutics
Influence of the high mobility group A1 genetic polymorphism on indices of metabolic syndrome and insulin resistance in the Iraqi population: Case-control study
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The high mobility group A1 gene (HMGA1) rs139876191 variant has been related to metabolic syndrome and type 2 diabetes, but data are lacking in Middle Eastern populations. The study aimed to assess whether the HMGA1 rs139876191 variant is associated with metabolic syndrome risk and whether this variant predicts the risk of insulin resistance. This case-control study was carried out at single center in Kirkuk city/ Iraq from February to August 2022. Polymorphisms in HMGA1 and genotyping were identified by Sanger sequencing of genomic DNA obtained from 91 Iraqi participants (61 patients with metabolic syndrome and 30 control). Lipid profile, serum (glucose and insulin), glycated hemoglobin, blood pressure, body mass index, and waist circumfer

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Publication Date
Sun Sep 01 2019
Journal Name
Journal Of Engineering And Applied Sciences
The role of e-Government on corruption and its impact on the financial performance of the government: An empirical analysis on the Iraqi government
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This study aimed to provide a conceptual model for the use and benefits of the e-Government as related to administrative fraud and financial corruption. The study also looked into their concepts, forms, dimensions and types and the role of e-Government on fraud reduction, corruption in administration and finance and its impact on the government performance. From the result, it is revealed that there is need for electronic government for implementation in order to curb the rate of fraud and administrative and financial corruption and improve the quality of service provision for better performance

Scopus (15)
Scopus
Publication Date
Mon Oct 01 2018
Journal Name
Journal Of Educational And Psychological Researches
Conflict management and its relation to functional performance as perceived by secondary school managers toward the directors of directorates of education in wassat province
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The research aims to; identify the management of conflict as perceived by secondary school managers toward the directors of directorates of education in wassat province, identify functional performance as perceived by secondary school managers toward the directors of directorates of education in wassat province. Besides, explore the relationship between Conflict management and functional performance among the directors of directorates of education in wassat province. A descriptive approach deemed more appropriate with study design. As a tool to collect the data of current research, the author used a questionnaire. Spss tools were used for data analysis

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Publication Date
Fri Apr 01 2016
Journal Name
Journal Of Economics And Administrative Sciences
Empowerment administrative Factors and its impact on Performance of the service organization An analytic Research at the Ministry of Interior – General Directorate of Traffic
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Abstract

The research study about the empowerment as an independent variable, in which details include (training and improvement, incentives, information sharing, trust, and delegation), has also focused on the performance of the service organization as a dependent variable in all dimensions which include (improve work efficiency, building the core competencies, focus on the beneficiary of the service, increasing the feeling of satisfaction of the employees, and the organizational support commitment). The research has been based on the opinions of a chosen sample of 75 service officers of the Ministry of Interior who work at the General Directorate of Traffic. The research problem has been identified by t

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Publication Date
Sun Apr 23 2017
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
The Construction of Complete (kn,n)-Arcs in The Projective Plane PG(2,11) by Geometric Method, with the Related Blocking Sets and Projective Codes
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   In this paper,we construct complete (kn,n)-arcs in the projective plane PG(2,11),  n = 2,3,…,10,11  by geometric method, with the related blocking sets and projective codes.
 

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Publication Date
Wed Oct 11 2023
Journal Name
Journal Of Educational And Psychological Researches
The Effectiveness of Cognitive-Behavioral Counseling in Reducing Symptoms of Social Anxiety and Improving Social Skills among Intermediate School Students in Dhi Qar Governorate
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The study aims to investigate the effectiveness of cognitive-behavioral counseling in reducing symptoms of social anxiety and improving social skills among a sample of intermediate school students in the city of Souq Al-Shuyukh at Dhi Qar Governorate. The sample consisted of (40) female students, their ages ranged (14-15). They were selected based on their high scores on the social anxiety scale. The sample was divided into two groups: an experimental group, and a control group, equal in number (20) students in each group. The researcher used the social anxiety scale and the social skills scale. In addition, he used the cognitive-behavioral counseling program, consisting of (11) counseling sessions, with a rate of (45) minutes per sessio

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