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A New Biological System For Detecting Environmetal Carcinogens And /Or Mutagenes And Their Adversary
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A  new  test  system  for  detecting  environment  carcinogenes and/or  mutagenes  and  their  adversary  It  has  been  induced.  One hundred and fifty   mutants   were isolated from   the basidiomycete fungus Coprinus cinereus   which were   resistant to guanine analogue S- az.aguanine .All the spontaneous and induced with UV light origin mutants were isolated from the wild type strains Bc9/6.6 and  Hd5.5

.These mutants were te ted on selective medium containing  different

concentrations of the analogue and also to their ability to usc purine bases and their degredated  products as  a sole  nitrogene source were tested ; and their ability to grow on HAT   medium was tested . According  to  the results obtained  from these test;  mutants  were

classified into four phenotypic groups for each  iJd -type strain .

All  the  8-az.aguanine  resistant  mutants  were  d.ikaryotized   with

compatible wild strains. The dikaryons produced were unable to grow on  medium           containing        8-az.aguanine                     which               establish the recessiveness of the mutations to their respective wi ld-type alleles. Complementation   test  detcrmind  four  genes   which  controll   the resi stance  to 8- azaguaninc in Coprinus cincres   .These genes were desi gnated  azg-1, azg-2, azg'-3, azg-4.Three of these genes azg-1, azg-2 and azg'-4werc carried by Bc9/6.6 and Hl /5.5 mutants. While, azg-3 gene  was found in Bc9/6.6 mutants only.

These  genes  are determ.ind for  the  first  time  in  fungus coprinus cinereus  .

Mutants which carry azg-1  gene were characterized by their inability to use   hypozanthine and                                              guanine as a sole nitrogen source in the

medium ; their failure to grow  on HAT medium  and their resistance

to all concentrations of 8- az.aguanine used.This gene is considered to

 

 

 

 

IBN AL- HAITHAM J.FOH PURE & API'L.SCI.         VOL.19(4) 2006

 

represent  a mutation led to   lose or   modify the specificity of the enzyme hypoxauthine -guanine phosphoribosyl transferase (HGPRT) whi ch play an important role in transferring hypoxauthine and guanine to their nucleotides  by salvage pathway.

Spore analysis indi cated that azg'-1  gene locted in linkage group II

,since it gave a distance of 28 map units with the mating type gene

B.

The assessment of the cytotoxic , mutagn ic and antimutagc•tic role of

the  aqueous extract of  garl ic     (Allium  sativum  L.)  against the genotoxic effect of mitomycin - C

( MMC ) evaluate the ability of the mutagen to induce mutation in

HGPRT gene by    using the asexual spores (oidia )of Copninus cineraus for the strain AZG78 and by depending on the viabil ity and mutation rate in HGPRT gene test .To assess cytotoxity and mutagenecity of garlic extract , gradual concentrations were prepared . The concentration of choice was considered with respect to  two factors ; high survi val rate and low mutagenic  activity (similar to negative control ). To examine the antimutagenic  effects of  the extract, an interation was made between the crude  extract and the mutagen   MMC with respect to three kinds of treatments before , aOer and with mutagen . The study concentrated on two sides 1- on the toxic and /or m utagenic effect of the aqueous extract of garlic . 2 - Antimutagenic activity of the extract with respect to   the mutageen MMC . However,   this activity was dependent on the type of the treatment . The extract showed best antimutagenic activity when it was used before the mutagen , so itis considered as desmutagen to the genotox i c effects of MMC.

These data support the hypothesis that garlic compounds may be eflicacius in preventions of cancer and also we could use the HGPRT

gene as  a  sensitive biological  system  in  detecting environmental mutagenes or carcinogens and their adversary .

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Publication Date
Tue Feb 05 2019
Journal Name
Journal Of The College Of Education For Women
System of governance and administration in the state of the Ottoman Algeria (1518-1830)
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Algeria is one of the states that are important to the Ottoman state, because of its geographic location is important to the Mediterranean Sea, as well as the economic resources of the nature of its soil geography and climate,diverse, making it the focus of attention of the Ottomans, along with the van, which has increased the interest of the Ottomans in Algeriais the fall Andalusat the hands of the Spaniardsin1492, and force the Muslims to get out of them, and did not Only Europeans do it, butrushed to the prosecution of Muslims tothe coast of North Africa and seizing control of manyofits ports and cities, prompting the Ottoman state to go forth and back to the barn Muslims,Especially after hehad appealed to the Arabs of the Ottoman sta

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Publication Date
Sun Jul 09 2023
Journal Name
Journal Of Engineering
An Investigation into Thermal Performance of Mist Water System and The Related Consumption Energy
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Experimental tests were conducted to investigate the thermal performance (cooling effect) of water mist system consisting of 5μm volume median diameter droplets in reducing the heat gain entering a room through the roof and the west wall by reducing the outside surface temperature due to the evaporative cooling effect during the hot dry summer of Baghdad/Iraq. The test period
was Fifty one days during the months May, June, and July 2012. The single test day consists of 16 test hours starting from 8:00 am to 12:00 pm. The results showed a reduction range of 1.71 to 15.5℃ of the roof outside surface temperature and 21.3 to 76.6% reduction in the daily heat flux entering the room through the roof compared with the case of not using w

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Publication Date
Tue Oct 08 2002
Journal Name
Iraqi Journal Of Laser
Laser Detection and Tracking System Using an Array of Photodiodes with Fuzzy Logic controller
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In this work laser detection and tracking system (LDTS) is designed and implemented using a fuzzy logic controller (FLC). A 5 mW He-Ne laser system and an array of nine PN photodiodes are used in the detection system. The FLC is simulated using MATLAB package and the result is stored in a lock up table to use it in the real time operation of the system. The results give a good system response in the target detection and tracking in the real time operation.

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Publication Date
Mon Sep 01 2014
Journal Name
Journal Of Accounting And Financial Studies ( Jafs )
Electronic payments system and its relationship to the effectiveness of commercial banks: Applied Research
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      That the electronic payments system plays an important role in the effectiveness of commercial banks by attracting domestic or foreign investors, especially in the banking sector , It must keep abreast of global developments and technology in the field of banking that lead to the effectiveness of the bank by providing modern banking services and good customer service that improves the reputation of the bank, as well as develop its activities and promotes economic development at the country level , The technological progress of the bank will increase the speed of conducting banking operations, accuracy and safer , here should be laws and regulations related to electronic payment systems keep pace with the la

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Publication Date
Mon Apr 20 2020
Journal Name
International Medical Journal
Cleaning efficacy and instrumentation time using rotary file system in primary molars (comparative study)
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ABSTRACT— In primary teeth, root canal treatment is a time consuming and challenging procedure, particularly during the most important step in endodontic treatment which is the preparation of the canal. Pulpectomy is the treatment of choice in all the necrotic primary teeth. For better treatment protocol, advancing technology brought the rotary system to reduce the manual dexterity and improve the quality of treatment for pulpectomy. This study aimed to compare and assess the efficacy of cleaning and the time required for the instrumentation during the preparation of root canals of the primary molars using the rotary and the manual (conventional) systems. Thirty root canals of primary teeth were selected. These teeth submitted to a

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Publication Date
Tue Sep 01 2020
Journal Name
Baghdad Science Journal
Developing Arabic License Plate Recognition System Using Artificial Neural Network and Canny Edge Detection
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In recent years, there has been expanding development in the vehicular part and the number of vehicles moving on the roads in all the sections of the country. Arabic vehicle number plate identification based on image processing is a dynamic area of this work; this technique is used for security purposes such as tracking of stolen cars and access control to restricted areas. The License Plate Recognition System (LPRS) exploits a digital camera to capture vehicle plate numbers is used as input to the proposed recognition system. Basically, the proposed system consists of three phases, vehicle license plate localization, character segmentation, and character recognition, the License Plate (LP) detection is presented using canny edge detection

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Publication Date
Thu Dec 06 2018
Journal Name
Iraqi Journal Of Pharmaceutical Sciences ( P-issn 1683 - 3597 E-issn 2521 - 3512)
Formulation and Characterization of Bromocriptine Mesylate as Liquid Self-Nano Emulsifying Drug Delivery System
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Bromocriptine mesylate is a semisynthetic ergot alkaloid derivative with potent dopaminergic activity, used in the treatment of pituitary tumors, Parkinson's disease (PD), hyperprolactinaemia, neuroleptic malignant syndrome, and type 2 diabetes ,the oral bioavailability is  approximately 6%, therefore aim  its  prepare and evaluate bromocriptine mesylate  as liquid self nano emulsifying drug delivery system to enhance its solubility , dissolution and stability . Solubility study was made in different vehicles to select the best excipients for dissolving bromocriptine mesylate. Pseudo-ternary phase diagrams were constructed at 1:1, 2:1, 3:1 and 4:1 ratios of surfactant and co-surfactant, four formulations were pre

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Publication Date
Tue Jan 31 2023
Journal Name
International Journal Of Nonlinear Analysis And Applications
Survey on intrusion detection system based on analysis concept drift: Status and future directions
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Nowadays, internet security is a critical concern; the One of the most difficult study issues in network security is "intrusion detection". Fight against external threats. Intrusion detection is a novel method of securing computers and data networks that are already in use. To boost the efficacy of intrusion detection systems, machine learning and deep learning are widely deployed. While work on intrusion detection systems is already underway, based on data mining and machine learning is effective, it requires to detect intrusions by training static batch classifiers regardless considering the time-varying features of a regular data stream. Real-world problems, on the other hand, rarely fit into models that have such constraints. Furthermor

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Publication Date
Mon Dec 01 2014
Journal Name
Advances In Engineering Software
System identification and control of robot manipulator based on fuzzy adaptive differential evolution algorithm
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Publication Date
Tue Sep 01 2020
Journal Name
Baghdad Science Journal
Developing Arabic License Plate Recognition System Using Artificial Neural Network and Canny Edge Detection
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            In recent years, there has been expanding development in the vehicular part and the number of vehicles moving on the roads in all the sections of the country. Arabic vehicle number plate identification based on image processing is a dynamic area of this work; this technique is used for security purposes such as tracking of stolen cars and access control to restricted areas. The License Plate Recognition System (LPRS) exploits a digital camera to capture vehicle plate numbers is used as input to the proposed recognition system. Basically, the proposed system consists of three phases, vehicle license plate localization, character segmentation, and character recognition, the

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Scopus (10)
Crossref (5)
Scopus Clarivate Crossref