Piperine, a crystalline alkaloid compound isolated from Piper nigrum, piper longum, and other types of piper, has had many fabulous pharmacological advantages for preventing and treating some specific diseases, such as analgesic, anti-inflammatory, hepatoprotective, antimetastatic, antithyroid, immunomodulatory, antitumor, rheumatoid arthritis, osteoarthritis, Alzheimer's, and improving the bioavailability of other drugs. However, its potential for clinical use through oral usage is hindered by water solubility and poor bioavailability. The low level of oral bioavailability is caused by low solubility in water and is photosensitive, susceptible to isomerization by UV light, which causes piperine concentration to decrease. Many different

       This paper uses Artificial Intelligence (AI) based algorithm analysis to classify breast cancer Deoxyribonucleic (DNA). Main idea is to focus on application of machine and deep learning techniques. Furthermore, a genetic algorithm is used to diagnose gene expression to reduce the number of misclassified cancers. After patients' genetic data are entered, processing operations that require filling the missing values using different techniques are used. The best data for the classification process are chosen by combining each technique using the genetic algorithm and comparing them  in terms of accuracy.

In this paper, we investigate some methods to solve one of the multi-criteria machine scheduling problems. The discussed problem is the total completion time and the total earliness jobs  To solve this problem, some heuristic methods are proposed which provided good results. The Branch and Bound (BAB) method is applied with new suggested upper and lower bounds to solve the discussed problem, which produced exact results for  in a reasonable time.

    The depth conversion process is a significant task in seismic interpretation to establish the link between the seismic data in the time domain and the drilled wells in the depth domain. To promote the exploration and development of the Subba oilfield, more accurate depth conversion is required. In this paper, three approaches of depth conversions: Models 1, 2, and 3 are applied from the simplest to the most complex on Nahr Umr Reservoir in Suba oilfield. This is to obtain the best approach, giving less mistakes with the actual depth at well locations and good inter/extrapolation between or away from well controls. The results of these approaches, together with the uncertainty analysis provide a reliable velocity model

      A specialized irradiation instrument "created instrument" was  designed and created from various kinds and sizes of available plastic household-waste materials. In addition, a neutron beam collimator with a lid was designed  and implemented. The collimator is with dimensions of 25 cm in height and 10 cm in inner diameter, while the lid dimensions are 11.5 cm height and outer diameter of 9.9 cm  to perfectly match the inner diameter of the collimator with the possibility of movement (opening and closing), and also the shielding of the radioactive ²⁴¹Am/Be neutron source with a recent activity of 37.5 mCi.

To investigate the efficiency of the "created instrument", ten hydrogenous material samples (ordinary p

  The purpose of this work is to determine the points and planes of 3-dimensional projective space PG(3,2) over Galois field GF(q), q=2,3 and 5 by designing a computer program.

In this paper, variable gain nonlinear PD and PI fuzzy logic controllers are designed and the effect of the variable gain characteristic of these controllers is analyzed to show its contribution in enhancing the performance of the closed loop system over a conventional linear PID controller. Simulation results and time domain performance characteristics show how these fuzzy controllers outperform the conventional PID controller when used to control a nonlinear plant and a plant that has time delay.

In this paper, a single link flexible joint robot is used to evaluate a tracking trajectory control and vibration reduction by a super-twisting integral sliding mode (ST-ISMC). Normally, the system with joint flexibility has inevitably some uncertainties and external disturbances. In conventional sliding mode control, the robustness property is not guaranteed during the reaching phase. This disadvantage is addressed by applying ISMC that eliminates a reaching phase to ensure the robustness from the beginning of a process. To design this controller, the linear quadratic regulator (LQR) controller is first designed as the nominal control to decide a desired performance for both tracking and vibration responses. Subsequently, discontinuous con

The study presents the modification of the Broyden-Flecher-Goldfarb-Shanno (BFGS) update (H-Version) based on the determinant property of inverse of Hessian matrix (second derivative of the objective function), via updating of the vector s ( the difference between the next solution and the current solution), such that the determinant of the next inverse of Hessian matrix is equal to the determinant of the current inverse of Hessian matrix at every iteration. Moreover, the sequence of inverse of Hessian matrix generated by the method would never  approach a near-singular matrix, such that the program would never break before the minimum value of the objective function is obtained. Moreover, the new modification of BFGS update (H-vers