fhe .rudy has shad a light on the abi_ lity Qf aq,ueous. extract of
Mairlr:aria chamomile ibr eliminating growth of miconazole. .resistant
muta.nt of Candida albk·afzy. whi-ch i:,solated from . human. ruiil and vagina ;Tfl- inimJ.tJTI inhibition cohc!:lhtra_tion (MIC) is l6 Jrl'g/n: l. Spon-taneous tesistant .mutatiqns-.fot mic-onazole were also is:ola ed by using sp 1-f.g/ml of rni:comlzoJeThis ::onc ntrf}:ti:o:n is five times more than the MIC .Different c<:n'lcentnrtlo·ns. of aqu pus e trac.t of Mchr:ztno}Jiile'· ranging betweep 0.625 and 50 -:tg/ml w·.ere also -qsed
.The effec,t 9£ tb_ec- :ornc.entrations on the grov-.111 of isoJated Candida C:O!oi:lieS were sli0:wed a grf!QUal decreasing .ih the CQioni:es nqrnbe.tS after, increasing the aqueous extfact onc :mt-t:a,tions. One concentration of aqQegus e-xtrat was selected as optimal conc.;:ntr-atian. .This selected tbBcentration ws ;g ve sixn,jl· viabllity for the Candida.
isolate$ in comparison with th.e · controJ @'O\lp. The test of interacting
impact fo.r the optimal eoncentr_atioR 'With Candida Golonies _growtlL we.r'Studred wfth three tieatn1 nts; befo-r,. after arid with the m'iconazole antibjqti . The esults ·showed tlutt the optimal selected cor.mentratiort o£ aqueous exttact was q : i-te: effi.cient in r-educing the num:per 'Qf miconazole tesistant mutants co1onie.s before and in the· presence of micon:az.-qte . lo conclusion, the aqu ous ·extract .o:f M· cham.Qmile was. · considered s one q_£ :the direct i-nhibitocs for th miconazole resi!?t' rnutants of C(.mditla albicqns.
