The aim of this study was toward the possibility of producing antigen that has the ability to stimulate the immune response against the infection with the hydatid cyst. To do so antigens were extracted from sheep hydatid cyst fluid of Echinococcus granulosus .These were: 1- The hydatid cyst fluid called antigen B. 2- Excretion-secretion called ES antigen. 3-B/ES antigen is a mixture (1:1) of the above two antigens. Three concentrations (15, 30 and 60 µg/ml) from antigen B/ES were prepared to immunize the white mice (males) with 20 µg/gr body weight and one booster dose (10 µg/gr) to stimulate immunity. The efficiency of these antigen concentrations against secondary infections was investigated by the calculation of the reduction in percentage of cysts numbers The results revealed that the reduction percentages of cyst in immunized group were 91.5% , 92.3% and 100% for concentration antigen 15, 30 and 60µg/g for Thr Immunized groups respectively.. There was a significant difference (p≤0.05) between and the positive control group infection. After 45 days of infection, the sensitivity test showed that the highest cellular immune response occurred after three hours of the injection of the B/ES antigen in the left footpad of the animals. This response was measured through the increase in the thickness of the footpad. The reaction was clear in the positive control and in the infected immunized animals. When the test was repeated after 90 days of the infection, the results were similar to the above, but the reaction was more acute than in the first time especially in the positive control groups of mice.
Curcumin is a yellow pigment produced from the rhizomes of the Curcuma longa plant and a primary chemo preventive component of turmeric is used as a spice and food coloring ingredient. Curcumin has a large number of pharmacological activities, such as anticancer, anti-diabetic, antioxidant, anti-infectious, and anti-inflammatory properties.Investigation of the geno-protective effect of curcumin on methotrexate induces chromosomal aberrations of spleen and bone marrow cells. In this study, 32 mice were used and divided into four groups (eight mice at each group) as follows: Group1 (negative control): Dimethyl sulfoxide was given intraperitoneally to mice every day for ten days.Group2 (positive control): Mice were received a single do
... Show More
(2)
(1)
The efficacy of five insect growth regulators has been tested against white fly larva Alearoclava jasimini on citrus tree orchards. Data from field tl'ia ls con finned that percent mortalities were 43.7, 33.9, 23.7, 20.8 and 12.3 for Admiral ( I miL) pyriproxefen, Nomol t 1 5 SC (!milL) Teflubenzuren , Match 050 EC ( I milL ) Lufenuren , cascade I 0 F.C (
0.9mi/L) flufenoxaron, and Dimiline 10 EC ( I milL) Difluben- zuron. The result indicated that Admiral and Nomolt have a continuous effect for one month , so the treatment needs to be repeated for each four weeks. Also, Admiral and Nomolt effect against eggs hatching by 41. 3 % and
(1)
(1)
Irinotecan induced-mucositis is an inflammatory event of intestine caused by an increase in concentration of active metabolite 7ethyl10-hydroxycamptothecin (SN38) in the intestine. Irinotecan must first be converted by a carboxylesterase (CES) to the active metabolite (SN38), which is subsequently glucuronidated by the hepatic enzyme to SN38G. The SN-38G is deconjugated in the intestine to SN-38 via ?-glucuronidase produced by the intestinal bacterial flora, which accounts for SN-38 delayed intestinal mucositis of irinotecan. To study the protective effect of mentha in irinotecan-induced mucositis, intestinal mucositis induced by I.P injection of irinotecan (75mg/Kg/day) for 4 days. Mentha ethanolic extract orally administered to
... Show More
(15)
(1)
The role of specific amino acids namely cysteine, methionine, threonine and asparagine in the protection provided by vamin solution against B-lactam inhibition to E. coli was evaluated in vitro In minimal medium, cells were treated with 32 ug/ml of penicillin G, carbenciLlin, hostacillin, cloxacillin and cephalotin in the presence of specific amino acid supplementation. Deletion of specific amino acids from the media abolished the protection provided by vamin. Threonine was essential for the protection of cells against all tested antibiotics, while cysteine was essential for protection against carbencillin and sephalotin. Deletion of methionine or asparagine abolished the protection against carbencillin and to a less extent cephalotin.
... Show MoreBackground: To elucidate distinctive CT imaging features that allows a diagnosis of hepatic hydatidosis.
Patients and methods : The computed tomographic (CT) findings of 58 patients with sonographically detected cystic liver lesions were prospectively analyzed. These patients were
followed up until a final diagnosis was reached.
Results : By CT scanning we correctly localized and diagnosed 81 hepatic hydatid cysts in 50 patients. These were all proved by surgery or endoscopic retrograde cholangio-pancreatography (ERCP). Stage III and II hydatid cysts were the commonest types (29 % and 25 % respectively ). 52 % of the cysts were 5-10 cm at presentation. At CT, we identified some ancillary imaging fea
Background: Echinococcus granulosus is a one major species of medical and public health importance which causes cystic echinococcosis.Hydatid disease is able to modulate antiparasite immune responses, persist and flourish in humans.
Objective: The main objective of this study is to diagnostic value for hydatidosis and to identify the prevalence in human in two different areas of Baghdad city which include urban and rural areas. Evaluating hydatid fluid antigen and hydatid cyst wall antigen for diagnosis of cystic echinococcosis(CE). preparation ELISA kit for detecting specific antibodies in patients and relative sera is considered as an important step in determining the recurrent case after surgical opera
(1)
We presented here a 25years old lady with a multiple hatdtid cysts in lung and liver and spleen in large number in each organ. Which regarded inoperable and difficult to treared.We use medical treatment with antihelimenthes drugs in new regime and follow-up over 1year clinically, laboratory investigations, U/s and CT.scan. There was good disappearance of liver and spleen cysts with very good response in lungs.
Cranberry (Vaccinium macrocarpon) is a North American natural fruit. consumed as food and used for health promotion and prevention of various diseases. Aim. The present study was designed to evaluate the protective effect of cranberry fruit extract on nephrotoxicity induced by cisplatin in mice by measuring selected oxidative stress markers. Methods. Twenty-eight male albino mice were used in this study. The animals were divided into 4 groups as follows: Group I [Negative Control]/orally-administered normal saline for 7 successive days; Group II [Orally-administered cranberry fruit extract alone (200 mg/kg) for 7 successive days; Group III/Mice IP injection with cisplatin (12mg/kg) on day 7 and; Group IV [Orally-administered cr
... Show More