This study was carried out on 10 adult females of albino mice , aged 8 – 10 weeks and 24 – 27 gm weight . In addition to 10 males were used for mating in order to determine the effect of injection of bromocriptine on the early stages of pregnancy and this was observed by measuring the weights of some component of female reproduction . The animals were divided into groups : the first group as the control which were injected subcutaneously with normal saline , while the second group as the treated which were injected subcutaneously with 0.5 mg of bromocriptine throughout the time of the expermint ( 5 days ). The results showed that there was a significant decrease ( P < 0.05 ) in consumpation of food and boody weight before killing , and also in weights of overies and uteri of treated animals in comparison with control . The result also showed the influence of bromocriptine in inhibiting the levels of prolactin hormone and the appearance of its negative effect on the earlier stages of pregnancy in mice through effect on the ovaries and uteri of these animals .
The reaction oisolated and characterized by elemental analysis (C,H,N) , 1H-NMR, mass spectra and Fourier transform (Ft-IR). The reaction of the (L-AZD) with: [VO(II), Cr(III), Mn(II), Co(II), Ni(II), Cu(II), Zn(II), Cd(II) and Hg(II)], has been investigated and was isolated as tri nuclear cluster and characterized by: Ft-IR, U. v- Visible, electrical conductivity, magnetic susceptibilities at 25 Co, atomic absorption and molar ratio. Spectroscopic evidence showed that the binding of metal ions were through azide and carbonyl moieties resulting in a six- coordinating metal ions in [Cr (III), Mn (II), Co (II) and Ni (II)]. The Vo (II), Cu (II), Zn (II), Cd (II) and Hg (II) were coordinated through azide group only forming square pyramidal
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