"Adenosine deaminase (ADA)
5´-Nucleotidase (5´-NT)
AMP – deaminase (AMPDA)
ovarian cancer
chemotherapy."
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Adenosine deaminase (ADA; Ec: 3.5.4.4), 5´- Nucleotidase (5´– NT; Ec: 3.1.3.5), and AMP – amino hydrolase (AMP – deaminase AMPDA; Ec: 3.5.4.6) activities were measured in sera of ovarian cancer patients before surgery, and after chemotherapy.
The results indicated that ADA specific activity increased significantly (P<0.05), while 5´-NT and AMPDA specific activity decreased significantly
(P<0.05) in ovarian cancer patients before surgery in comparison with those of their corresponding control women and benign tumors groups.
When the activities of these enzymes were measured after chemotherapy, a significant decrease (P<0.05) in ADA activity, and a significant increase (P<0.05) in 5´- NT and AMPDA activities w
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