Type 2 diabetesmellitus . Glycemic control .HbA1c target .Obesity .Body weight . Liraglutide .Dose titration . Iraq
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Background This study aimed to evaluate the efficacy of once-daily liraglutide as an add-on to oral antidiabetics (OADs) on
glycemic control and body weight in obese patients with inadequately controlled type 2 diabetes (T2D).
Methods A total of 27 obese T2D patients who received 7 months (0.6 mg/day for the first month, 1.2 mg/day for
3 months, and 1.8 mg/day for 3 months) of liraglutide treatment as an add-on to OADs were included. Data on body
weight (kg), fasting plasma glucose (FPG, mg/dL), postprandial glucose (PPG, mg/dL), and HbA1c (%), were
recorded.
Results Liraglutide doses of 1.2 mg/day and 1.8 mg/day were associated with significant decreases in body weight
(by 8.0% and 11.9%, respectively, p < 0.01 for each) and HbA1c (by 20.0
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