This comprehensive review examines the efficacy and safety of tumor necrosis factor-alpha (TNF-α) inhibitors in treating various autoimmune diseases, and focuses on their application in Iraqi patients. Elevated TNF-α levels are linked to autoimmune disorders, leading to the development of anti-TNF-α therapies such as infliximab, etanercept, adalimumab, certolizumab pegol, and golimumab, which have gained FDA approval for conditions like psoriasis, in¬flammatory bowel disease, ankylosing spondylitis, and rheumatoid arthritis. While these therapies demonstrate sig¬nificant therapeutic benefits, including improved quality of life and disease management, they also carry risks, such as increased susceptibility to infections and pote

Theatrical art, from (Plato) to (Heidegger), passing through (Husserl) and (Husserl) has propagated the parallel relations between the overlapping formal patterns in the world of hypotheses crowded with diaspora and scattering, leading to the manifestations of implicit meaning in the intellectual and aesthetic discourse, through the deconstructive pattern that restructures The aesthetic image according to the aesthetic data to be employed, so the effectiveness of the deconstructive system had an important role in authorizing the Ghanaian logic and continuity on which the Western meta meaning was based, and the artistic scene was subjected to it in line with literature and art to be able to pay attention to the achievement and clarify it

In recent years, the attention of the international community and intergovernmental and non-governmental organizations has grown into a new dimension of population displacement, called displacement within the country as a result of conflicts and the expansion of tacit groups, using sentences to describe such conflicts as "identity-based conflict", "ethnic conflict" "Sectarian conflict", in an attempt to determine the nature and characterization of those conflicts. In such conflict-stricken conditions, the value of a citizen - a person not directly involved in the conflict - is measured by the potential gains that that person has made to the conflicting parties, as civilians have been indirect victims of military operations, Favor

underemployment

الخطاب السياسي الاسلامي واشكالية المراوحة بين الشورى والديمقراطية

Los enunciados interrogativos desempeñan un papel de sumo interés en el habla del ser humano en todo el mundo, además de la gran importancia que desempeñan sus distintos enunciados y partículas en abreviar las oraciones y hacer llegar a nuestro interlocutor nuestra intención con pocas palabras, por eso a través de esta investigación vamos a enfocar la luz sobre uno de sus tipos fundamentales "los enunciados interrogativos directos", a través de un estudio morfológico contrastivo entre el árabe y el español, este fue el principal motivo para elegir este tema.
A pesar de que los enunciados interrogativos directos aparentemente no ofrecen mucha dificultad, pero dominar a dicho tipo de enunciados con todas sus divisiones, sus

The penalized least square method is a popular method to deal with high dimensional data ,where  the number of explanatory variables is large than the sample size . The properties of  penalized least square method are given high prediction accuracy and making estimation and variables selection

 At once. The penalized least square method gives a sparse model ,that meaning a model with small variables so that can be interpreted easily .The penalized least square is not robust ,that means very sensitive to the presence of outlying observation , to deal with this problem, we can used a robust loss function to get the robust penalized least square method ,and get robust penalized estimator and

he public federal budget of the state includes estimated figures for state revenues and expenditures for the next fiscal year. The estimation process is one of the main parts of the preparation of the general budget of the state and the accuracy in the estimation of revenues and expenditures of the most important principles that should be based on the process of making estimates and should not overestimate the assessment process to ensure the availability of funds in the future in all cases, which lead to unfair distribution of allocations, so the research aims to study The case of preparing the budget in the Directorate and how to estimate the expenditure in, by the analysis of operating budgets and identify deviations in the implementa

José Echegaray, dramaturgo español, obtuvo premio Nóbel de literatura en (1904), político, orador, economista y dramaturgo. Con su obra "El gran Galeoto" en 1881, llegó a la cumbre de la popularidad.
Henrik Ibsen, dramaturgo noruega, creador del drama moderno, por sus obras realistas que abordan problemas psicológicos y sociales. Y a que fue el iniciador del teatro de tesis del teatro social. Ibsen, dramaturgo noruega, cuya obra influyó notablemente en el teatro europeo de finales del s. XIX y principios del XIX ; en gran parte en la obra de Echegaray, Galdós (1) y Benavente (2).
Los presentes autores empezaron sus producciones bajo el romanticismo que fue poco a poco añadiendo ideas del naturalismo y el realismo dramátic