...Show More Authors
The cytotoxic effect of catechol was examined in two human cancer cell lines, Epidermoid larynx carcinoma (Hep-
2), Cerebral glioblastoma multiforme (AMGM-5) and Murine mammary adenocarcinomacell (AMN3) treated with half
concentrations of catechol (1000, 500, 250, 125, 62.5 and 32.25 μM) for 72 hr. The get hold of results showed catechol have a
toxic effect of the cell viability of three types of cell lines after 72h of exposure, the toxicity was dependent on catechol
concentrations and/or autoxidation for quinines formation, there were a marked decreased of cell viability in a dose dependent
manner in all cell line types. Inhibition concentration of catechol for 50% of cell viability (IC50) were calculated, they were at
581.5 μM, 478 μM
...
Show More