Doxorubicin (DOX) is an efficient antineoplastic agent with a broad antitumor spectrum; however, doxorubicin-associated cardiotoxic adverse effect through oxidative damage and apoptosis limits its clinical application. Cafestol (Caf) is a naturally occurring diterpene in unfiltered coffee with unique antioxidant, antimutagenic, and anti-inflammatory activities by activating the Nrf2 pathway. The present study aimed to investigate the potential chemoprotective effect of cafestol on DOX-induced cardiotoxicity in rats. Wistar albino rats of both sexes were administered cafestol (5 mg/kg/day) for 14 consecutive days by oral gavage alone or with doxorubicin which was injected as a single dose (15 mg/kg intraperitoneally at day 14) to i

Cyclophosphamide which acts as cytotoxic alkylating agent can induce a renal damage through the toxic metabolites which result from metabolic activation of Cyclophosphamide by cytochrome P-450 inside hepatocyte and develop renal toxicity by direct binding with cellular organelles in the urinary tract cells. Guggulsterone is a sterol derived from plant has ability to bind to farsenoid X receptor, mineral corticosteroid receptor, androgen receptor, glucocorticoid receptor and estrogen receptor.

The gravity field of southern Iraq shows steep gradient of regional trend. The gravity contours over the anticline structures in this area do not show the closure characteristic of these structures. The effect of lateral density variation for Hormuz Salt complicates the case in the area. Higher derivatives are one of the means that have been used to remove the effect of such regional gravity variations, which can easily mask significant structures. Biharmonic Operator is used to delineate these distort structures, follow their extent and at the same time distinguish new features. The Biharmonic operator manipulation has ability to suppress the effect of regional and enhance the local anomalies. The problem with higher derivatives operati

Abstract

The current research aims to identify the effect of the proposed strategy in accordance with realistic mathematics on the achievement and mathematical Interrelation of third Intermediate students. Two samples were tested from the middle third grade in a school affiliated with the General Directorate of Baghdad- Rusafa, the first for the academic year (2022-2021). The experimental group is (30) students taught according to the proposed strategy, and the control group is (30) students based on the traditional method. To achieve the research objective, the researchers developed a test for achievement consisting of (30) items and a test of sports interconnection composed of (20) items. The results of the stu

         تعد البيئة في يومنا المعاصر من الجوانب التي توليها المجتمعات البشرية اهمية كبرى لما لها من انعكاسات مباشرة وغير مباشرة على حياة الانسان ،وصحته، ومتطلبات حياته ،وأمنه، ومستقره في اي مكان في العالم تبرز مشكلة البحث ، في ان ما من سبيل صحيح لآعداد الاجيال القادمة إعدادا بيئيا ألا من خلال زيادة الوعي البيئي باستعمال كافة الوسائل التربوية المتخصصة، فالمعلومات ضرورية ولكنها لاتمنح

إن الغرض من هذه الدراسة هو التعرف على مدى موضوعية التقييم في المواد التي ليس فيها امتحانات نهائية وهي التربيةُ العمليةُ ومشروعُ البحثِ وذلك بمقارنتها بالمعدل العام للتخرج. وقد أستعملت درجات 450 طالباً وطالبةً من خريجي كلية التربية في الجامعة المستنصرية للعام الدراسي 2003- 2004 ومن الدورين الأول والثاني في هذه الدراسة. وأشارت النتائج إلى وجودِ فروقٍ ذاتِ دلالةٍ إحصائيةٍ بين مادة التربية العملية والمعدل العا

In this research, the stopping power and range of protons in biological human soft and hard tissues (blood, brain, skeleton-cortical bone, and skin) of both child and adult are calculated at the energies ranging from 1MeV to 350 MeV. The data is collected from ICRU Report 46 and calculated the stopping power employing the Bethe formula. Moreover, the simple integration (continuous slowing down approximation) method is employed for calculating protons range at the target. Then, the stopping power and range of protons value in human tissues have been compared with the program called SRIM. Moreover, the results of the stopping power vs energy and the range vs energy have been presented graphically. Proper agreement is found between the gain

The research aims to recognize the impact of the training program based on integrating future thinking skills and classroom interaction patterns for mathematics teachers and providing their students with creative solution skills. To achieve the goal of the research, the following hypothesis was formulated: There is no statistically significant difference at the level (0.05) between the mean scores of students of mathematics teachers whose teachers trained according to the proposed training program (the experimental group) and whose teachers were not trained according to the proposed training program (the control group) in Pre-post creative solution skills test. Research sample is consisted of (31) teachers and schools were distribut

The goal of modern education is to achieve healthy growth of the individual and
society Since childhood is one of the most serious developmental stages in the human
identity, which is not limited to the threat to it stage the foundations of personal sound is
placed where the dimensions of the various components and based on the foregoing targets
Current Search: "Measuring the level of psychological health kindergartens"
And it included a sample search on the kindergarten children in the province of
Baghdad and achieve the objectives of research have been prepared in scale mental health and
concluded the researcher through the search results that kindergarten children suffering from
disorders in mental health, the