Obesity is a common disease that resulted from over-nutrition in adults and children. It rarely causes damage to the centers of food in the brain. Obesity is defined as an increased body weight from its natural limit which is resulted from the accumulation of excessive amounts of fatty tissue incredibly up to 20% in males, 30 % in females unless this increase is not due to an increase in muscles as in athletes or accumulation of water in the body which is resulted from Mesothelioma or the magnitude of the skeleton.Obesity is the increase of the total average of fat in the body compared to other tissues, which causes an increasing body weight, thereby increasing body mass. The fatty child has an increase in the stored fatty layer under the skin, and increased weight 20%more than the normal weight of other children in the same age and height.
This thesis focuses on identifying showing the relationship between obesity and some of the variables. Moreover, the thesis reflects the importance of maintaining the ideal weight of the child and his role in the growth and health. The evidence shows that children who suffer from obesity are more likely to become fat adults, so they are exposed to increased risk of serious health problems. Hence, protecting children from obesity and treating them is possible through changing lifestyle, improving the child's nutrition system, and urging him to exercise to improve their health at the present time and in the future.
Therefore, the thesis aims: to detect significant differences in obesity for kindergarten children depending on certain variables through the testing hypothesis as followed: Statistically there are no significant differences in obesity with kindergarten children that are attributable to the following variables:
(A)Sex variable.
(B) The sequence of the child in the family..
(C) Dietary habits of the family.
To achieve the objectives of this study, 300 children were selected as samples, 166 males and 134 females. One of the most important tools that were used is:
1 - an electronic device for measuring weight.
2 - Length measuring tape.
3 - Measurement of body mass index (BMI)..
The researcher used in data statistical analysis:
(1) One way Anova.
(2) The T- test for two independent samples: Independent Samples Test.
(3) The real bilateral correlation coefficient (Point Bay Cyril).
The most important results that have been reached:
(1) That females suffer from obesity more than males because the body mass index of females is greater than the body mass index (BMI) for males.
(2) There is no statistically significant difference between the averages of body mass index (BMI) scores for kindergarten children due to the variable of the sequence of the child within his brothers.
(3) There is no statistically significant difference between the averages of body mass index (BMI) scores for obese kindergarten children that is attributed to behavioral tendencies variable of the child.
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Allosteric inhibition of EGFR tyrosine kinase (TK) is currently among the most attractive approaches for designing and developing anti-cancer drugs to avoid chemoresistance exhibited by clinically approved ATP-competitive inhibitors. The current work aimed to synthesize new biphenyl-containing derivatives that were predicted to act as EGFR TK allosteric site inhibitors based on molecular docking studies.
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Abstract
Mitoxantrone is an antitumor agent used in the treatment of breast and prostate cancer, acute leukemia, lymphoma, and also in the treatment of multiple sclerosis due to its immunosuppressive properties. The mitoxantrone's cardiotoxicity is irreversible, dose-dependent, and it may occur years after treatment. Zinc is considered as an essential mineral for cell division and the synthesis of DNA and protein; furthermore, such mineral has an important role in states of cardiovascular diseases; and may have protective effects in coronary artery disease and cardiomyopathy.
Objective: The current study is designed to investigate effects of two different doses of zinc sulfat
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