Cancer is one of the critical health concerns. Health authorities around the world have devoted great attention to cancer and cancer causing factors to achieve control against the increasing rate of cancer. Carcinogens are the most salient factors that are accused of causing a considerable rate of cancer cases. Scientists, in different fields of knowledge, keep warning people of the imminent attack of carcinogens which are surrounding people in the environment and may launch their attack at any moment. The present paper aims to investigate the linguistic construction of the imminent carcinogen attack in English and Arabic scientific discourse. Such an investigation contributes to enhancing the scientists’ awareness of the linguistic conduct they follow in attracting people’s attention towards the risk of the approaching attack. The linguistic awareness also helps maintain better promotion of people’s pre-emptive responses that can reduce the potential for cancer cases. To achieve this aim, the paper adopts dual methodological procedures of qualitative and quantitative analyses. Cap’s (2013) proximization theory of threat and crisis construction is adopted for both qualitative and quantitative procedures. The mathematical calculations and statistical results for discourses in both languages are maintained by corpus linguistic analysis using Anthony’s (2019) software, AntConc. The paper has come up to certain conclusions that shed light on the similarities and differences in the construction of the imminent carcinogen attack in both languages. English scientific discourse has shown more reliance on temporal proximization to envisage the imminent attack of carcinogens against human bodies. Categories 1, 2, 3 and 5 are all more dominant in the English scientific discourse. However, both English and Arabic discourses show diversity in the density and employment of the lexico- grammatical tools (categories) that manifest the carcinogen attack.
على الرغم من أن الجامعات والمراكز والمؤسسات العلمية في الجامعات العراقية تزخر بالعديد من الكوادر والخبرات العلمية والأكاديمية المؤهلة علمياً وفنياً لانتاج البحوث العلمية والاشراف على طلبة الدراسات العليا، غير ان عملية انتاج الابحاث العلمية التطبيقية على وجه الخصوص تعترضها مجموعة من الصعوبات والمعوقات التي استطلعها الباحثين اما من خلال التجربة الشخصية, او من خلال استطلاعات اراء طلبة الدراسات العليا والب
... Show MoreOn the basis of known coumarin-based prodrug system, a novel coumarin-based mutual prodrug of 5-fluorouracil and dichloroacetic acid was designed, synthesized and evaluated as a promising oral chemotherapeutic agent basing on in vitro stability study in HCl buffer (pH 1.2) and in phosphate buffer (pH 7.4), as well as in vitro release study in human serum. The chemical structure of prodrug was confirmed by analyzing its FTIR, 1H NMR, 13C NMR and MS-ESI spectra. The results of in vitro kinetic study indicated that the prodrug was significantly stable in HCl and in phosphate buffers, and was hydrolyzed in human serum followed pseudo first order kinetics.
Keywords: Coumarin-bas
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