Background: Orthodontic tooth movement is characterized by tissue reactions, which consist of an inflammatoryresponse in periodontal ligament and followed by bone remodeling in the periodontium depending on the forces applied. These processes trigger the secretion of various proteins and enzymes into the saliva.The purpose of thi study was to evaluate the activity of alkaline phosphatase (ALP) in saliva during orthodontic tooth movement using different magnitude of continuous orthodontic forces.
Materials and Methods: Thirty orthodontic patients (12 males and 18 females) aged 17-23 years with class II division I malocclusion all requiring bilateral maxillary first premolar extractions were randomly divided into three groups according to the magnitude of the force application (40, 60 and 80gm). A sectional fixed appliance was bonded and designed to give labial force to the maxillary first premolar for three weeks. Unstimulated saliva was collected from the patients before force application, then 1 hour after force application, followed by 1 day, 7 days, 14 days and 21 days.Salivary levels of ALP were measured using spectrophotometer and compared with the baseline level.
Results: The results revealed that ALP enzymelevel increased with increasing magnitude of orthodontic force (from 40 to 80gm). This was statistically insignificant after 1 hour and 1 day of force application, but significant after 7, 14 and 21 days.The ALP level significantly increased from baseline after 7 days of force application and peaked at 21 day for all the three force levels.
Conclusions: The ALP level reflect the biological activity that takes place in the periodontium during orthodontic tooth movement, and therefore they can be used as a diagnostic tool for monitoring of correct orthodontic tooth movement in clinical practice.
The method of heavy metals deposition which is based on cobalt in detection of Carbonic anhydrase enzyme in the Sulcus median in the hid brain (fourth ventricle) in the adult white rat (Rutts rutts). An essential amended in the method has been done by using cobalt chloride (CoCl2) instead of cobalt phosphate (Co3(PO4)2) in the reaction medium. Any efficacy of enzymic histochemical for carbonic anhydrase enzyme did not show in histological sections. The floor of the fourth ventricle of the brain is specific, clearly any histochemical reaction sediments have not been found in sulcus median of the floor of the fourth ventricle. The corresponding stain to green methyl which was observed clearly in sulcus median region. The ventral surface of
... Show MoreA new heterocyclic Schiff bases ligand (HL) derived from condensation of 2-Amino-4-methylbenzothiazole with 4-Diethylaminosalicylaldehyde have been synthesized and characterized by (FTIR & UV.Vis) spectroscopies, (1H & 13C)NMR spectra, mass spectrum, elemental microanalysis (C,H,N,S). Metal complexes with Co(II), Ni(II), Cu(II), Zn(II) and Cd(II) ions have been also synthesized and characterized by (FTIR & UV.Vis) spectroscopies, flame atomic absorption, molar conductivity measurements and magnetic susceptibility. These studies indicate that the mole ratio (L:M) is (2:1) for Co(II) complex and (1:1) for other complexes. The spectral results indicate that the ligand coordinates with met
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The aim of this study was intended to study the effect of rifadin drug on lipids metabolism in the blood of the rabbits .Eight rabbits were used in the experiment ,they were divided into two groups ,first group(control group ) was administrated with 15mg/ml /day normal saline for 35 days ,while the second group (treated group )was administrated with (15/mg /kg/day) for 35 days of rifadin( capsule 300mg/kg).This study examined the influences of rifadin drug on the concentration of cholesterol , triglycerides , HDL ,LDL and VLDL in rabbits sera .The result showed that there were no significant increased (p>0.05) in cholesterol concentration in rifadin treated group compared with control group ,and th
... Show More The ceramics specimens as superconducting phase (Bi2PbxSr2Ca2Cu3O10+δ) with different concentrations of Pb from (0.0-0.5) were prepared by solid-state reaction method. Superconducting samples were exposed to high humidity (RH 75% at 25ºC) for seven weeks time interval. The humidity has a negative effect on the transition temperature of superconductor phase .It destroys the superconducting phase and the samples were converting to insulator.
Background: Levetiracetam is a member of the new antiepileptic drugs and has a broad spectrum effect, used as an adjunctive therapy in addition to monotherapy in the treatment of partial onset-seizures. The effect of levetiracetam on the development of embryo nervous system after maternal exposure during pregnancy has not been identified. Objective: to evaluate the effect of antiepileptic drug, levetiracetam (LEV) within its therapeutic dose 350mg/Kg body weight on albino female rat to clarify its effect on the developing cerebral cortex histologically. Material And Methods: Ten pregnant female rats were separated into two groups, control group and experimental group. They were obtained from the animal house of the high institute of inferti
... Show MoreExpansive soil spreads in Iraq and some countries of the world. But there are many problems can be occurred to the structures that built on, so we must study the characteristics of these soils due to the problems that may be caused to these structures which built on these kinds of soil and then study the methods of treatment. The present study focuses on improving the geotechnical properties of expansive soils by treating it Metakaolin(M). Metakaolin (M) has never been used before as an improvement material for stabilizing the expansive soil . Metakaolin is a pozzolanic material. It’s obtained by calcination of kaolinite clay at temperatures from 700°C to 800°C. Kaolin chemical composition is
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A chemical study was carried out to evaluate the efficiency of the liver enzyme concertation and uric acid level and its antagonists in the serum of the professors exposed to chemicals in the laboratories of the University of Samarra and their comparison with the healthy people. The research included 25 samples of the exposed professors and 20 samples as a group of officers.
The results of the current study showed a significant increase in the level of AST, ALT in the serum of professors exposed to chemicals compared to healthy people. The results showed no significant increase in
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