Background: Malignant lymphoma is the generic term given to tumors of the lymphoid system and specifically of lymphocytes and their precursor cells, While all lymphomas are malignant neoplasms, there is a wide spectrum of clinical behavior, with some following an indolent clinical course and others behaving in an aggressive manner (will causing death in a short time frame if left untreated). The metastatic process involves intravasation and extravasation of tumor cells, followed by reimplantation of tumor cells, formation of a new tumor stoma, Degradation of the extracellular matrix and components of the basement membrane by proteases facilitates the detachment of tumor cells, their crossing of tissue boundaries, and invasion into adjacent tissue compartments. The importance of tumor-associated proteases in invasion and metastasis has been demonstrated for a variety of solid malignant tumors. MMP family has been implicated in tumor cell invasion and metastasis. Material and methods: This study included 67 formalin-fixed, paraffin-embedded histopathologically diagnosed lymphoma blocks (head and neck lesions), 24 Hodgkin’s Lymphoma and 43 Non Hodgkin’s Lymphoma. Immunohistochemical (IHC) evaluation of MMP-9 monoclonal antibodies), in relation to the clinicopathological parameters was assessed. Results: The mean of expression of MMP-9 in NHL was higher (65.4±18) than that in HL (56.7±21.4) though it did not reach the level of statistical difference P > (0.05), while the mean of expression of MMP-9 in relation to tumor grades was different as it had a value of (72±14.1) in low grade tumors, (68.3±15) in the intermediate grade tumor and (61.4±20.7) in high grade tumors; consequently, this difference did not reached the level of statistical significance P(ANOVA) >0.05 . MMP 9 had no statistical significant correlation in regard to its mean in HL subtypes. Conclusions: This study had shown that there was no significant correlation between age and mean of expression of MMP-9 in HL and NHL. There was no statistical significant difference in the mean of expression of MMP-9 between HL and NHL subtypes. Keywords: MMP-9, local invasion, Hodgkin’s lymphoma, Non Hodgkin’s Lymphoma.
The Tamarix aphylla is a wild perennial shrub with erect stems that are long and glabrous. They have leaves that are simple, alternate, sheathed, and the apex of the blade is acuminate. And a scaly clawed bract and the the inflorescences were simple, spike-like. The pistil consists of ovary pyramidal, 3 styles, and 3 stigmas. The androecium consists of five stamens that are antisepalous. The perianth was distinct with five sepals and five petals. The fruits were capsule-shaped, pyramidal, and smooth. The seed has an apical pappus of unicellular hygroscopic hairs; endosperm is absent. The anatomical study of the leaves contained a uniseriate epidermis consisting of one layer of elongated cells covered by a layer of papillary cuti
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Diabetic kidney disease is an illness of the glomerulus that interferes with the glomerular filtration barrier (GFB), which is worked to enable kidney to selective purification of water and solutes in addition to limiting the movement of large macromolecules such as albumin. In the glomerular endothelium, mesangial cells, foot cells, and the brush border of the proximal tubules, ACE-2 is expressed and that the kidneys represent the highest-expressing region of this enzyme. Thus, the current study aimed to evaluate ACE-2 level in this case compared to healthy condition. The study Conducted with 120 male and female ranging in age (30-65) years old. Ninety patients with type 2 diabetes subdivided into three groups on the basis of A
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Young people represent the power and cornerstone of societies and their superiority is linked to their well-being. Their empowerment is as essential as the heart to the body, if it is corrupt, then the whole body is corrupt, and vice versa. The exposure to extremism and pressure from their families leads to violent acts and crimes for obtaining money through unknown organized bodies. This will drive them to fail in their life in an attempt to fulfill their most basic needs, which they have been deprived of by their families, the government, and other institutions. Therefore, governments should provide job opportunities for young people and provide entertainment centers, sports clubs, and family education centers that raise awareness of s
... Show MoreThe world and the business environment are constantly witnessing many economic changes that have led to the expansion of the business' volume due to mergers and the increase in an investments volume and the complexity of business and the transformation of some systems, which was reflected on the size of the risk and uncertainty which led to necessity of a presence of transparent and objective accounting information In the way that reflects the financial performance of the economic units to be available to all users of that information, therefore, The need for the existence of indicators for transparency in the disclosure of accounting information that these units adhere to. Standards & Poor's indicators, which included items
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Background: Type 2 diabetes mellitus (T2DM) characterized by insulin resistance (IR) and progressive decline in functional beta (β) cell mass partially due to increased β cell apoptosis rate. Pancreatic stone protein /regenerating protein (PSP/reg) is produced mainly by the pancreas and elevated drastically during pancreatic disorder. Beta cells are experiencing apoptosis that stimulate the expression of PSP/reg gene in surviving neighboring cells, and that PSP/reg protein is subsequently secreted from these cells which could play a role in their regeneration.
Objectives: To analyze serum levels of PSP/reg protein in T2DM patients and evaluate its correlation with the microvasc
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Liquefied petroleum gas (LPG), Natural gas (NG) and hydrogen were all used to operate spark ignition internal combustion engine Ricardo E6. A comparison of CO emissions emitted from each case, with emissions emitted from engine fueled with gasoline as a fuel is conducted.
The study was accomplished when engine operated at HUCR for gasoline n(8:1), was compared with its operation at HUCR for each fuel. Compression ratio, equivalence ratio and spark timing were studied at constant speed 1500 rpm.
CO concentrations were little at lean ratios; it appeared to be effected a little with equivalence ratio in this side, at rich side its values became higher, and it appeared to be effected by equivalence ratio highly, the results s
... Show MoreBackground: Penetrating neck injuries are common problem in our country due to increasing violence, terrorist bombing and military operations.
These injuries are potentially life threating and need great attention and proper management.
Objective: The aim of this study is to focus on the importance of anatomical zonal classification of the neck in the management of penetrating injuries of the visceral compartment of the Neck.
Methods :70 patients with various injuries who were managed at causality unit and Otolaryngology department in Al-Kindy Teaching Hospital during aperiod from January 1st 2015 to October 31st 2015.
The study carried on those patient depending on proper clinical examination and their urgent management.