Background: It has been well known that the success of mandibular implant- retained overdenture heavily depends on initial stability, retention and long term osseointegration this is might be due to optimal stresses distribution in surrounding bones. Types of mandibular implant- retained overdenture anchorage system and number of dental implants play an important role in stresses distribution at the implant-bone interface. It is necessary to keep the stresses below the physiologic tolerance level of the bone .since. And it is difficult to measure these stresses around bone in vivo. In the present study, finite element analysis used to study the stresses distribution around dental implant supporting Mandible implant retained overdenture Materials and methods: Eight models were constructed including four designs of anchorage system (ball-cup, ball-O Ring, bar without distal extension and bar with distal extension).The first group of models were supported by four dental implant and second group of models were supported by two dental implant only. Models constructed from the data obtained directly from patient The contour of bone was obtained from C.T scan image of patient, then data transferred to ANSYS program for modeling then load applied and solve the equation by the program, Specified nodes were selected at the rings of crestal bone (cortical bone) and cortical cancellous interface around each dental implant and fixed for all models to monitor the stress change in that regions of different design of MIR-OD.. After load application, Specified nodes were selected at the rings of crestal bone (cortical bone) and cortical cancellous interface around each dental implant and fixed for all models to monitor the stress change in that regions of different design of MIR-OD . Results: In the present study the stress distribution and maximum stresses value around dental implant had a relationship to the number of dental implant. , The result appeared that the maximum stresses and means of stresses value was lower in the first group of models (which was supported through the use four dental implant) than the second group of models (which was supported through the use of two dental implant only). For the first group of models the maximum stresses value around mesial implant was11.67, 10.51, 10.98 and 10.72 Mpa, while the maximum stresses around distal implant was 21.33, 18.51, 18.86, and17.56 Mpa for models 1,2,3 and 4respectively ,and the stresses around implant supporting second group of models was 22.52, 22.16, 20.51 and 19.60 Mpa for models 5,6,7and8 respectively .Statistical analyses of means value appeared that there was statistically significant difference in stresses means value around implant of the second group with that’s values around mesial and distal implant supporting first group of model . Regarding the result of both ball and bar system, it has been demonstrated that stress was greater with ball attachment and MIR-OD supported by the use of four dental implants and anchored by bar attachments with distal extension gives the minimum values of stresses than the rest models. Also the results show that higher stresses value was appeared at the cortical bone ring surrounding dental implant especially the distal implant nearest to the free end extension area. Also it was appeared that the best model was Mandible implant- retained overdenture that’s anchored by bar with distal extension and support by four dental implant. Conclusions: Bar-clips with distal extension mode of attachment considered the best type in producing the least stresses around dental implant regardless number of dental implant used.
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The aim of the study was comparative between oxidative stress in diabetes mellitus using the measurement of some biophysical and biochemical parameters on two groups of diabetic patients, were conducted in the Al-Yarmuk Teaching Hospital,30 patients insulin dependent diabetes mellitus (IDDM) or type 1 ,their ages ranged between (15-45) and30 patients non- insulin dependent diabetes mellitus (NIDDM) or type 2,their ages ranged between (42-65).This study has been compared with 30 healthy subjects. The present study was demonstrated to evaluate the alteration in oxidative stress as measured by plasma and red blood cells Malondialdehyde (MDA) andchanges in antioxidant mechanism as measured by plasma and red blood cells Glutathione (GSH)
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DBN Rashid, Rimak International Journal of Humanities and Social Sciences, 2020
Abstract Background: Acute myeloid leukemia (AML) results from sequential genetic alterations in a normal hematopoietic stem cell or its progenitors giving rise to an autonomous clone that dominates the bone marrow leading to marrow failure. MicroRNAs are short non-coding nucleic acid sequences that regulate post-transcriptional gene expression by base-pairing with their target mRNAs. MiRNAs can be secreted into extracellular fluids and carried to target cells by vesicles or bound to proteins. Intracellular and circulating miRNAs are believed to be useful markers in the diagnosis, prognosis, and treatment of various cancers. Practically, circulating miRNAs are more stable at room temperatures and extreme conditions. Purpose: This study aim
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The study aimed to compare the expression of miR-126-3p and miR-423-5p in patients and normal subjects, and correlate their expression with response to induction therapy. Circulating miR-126-3p and miR-423-5p were measured in the plasma of 43 adult AML patients and 35 age- and sex-matched controls by real time PCR. The foldchange in differential expression for each gene was calculated using the comparative cycle threshold (CT) method (also known as the 2−CT method). For statistical purposes, the fold change was calculated using DDCT (or 2–∆∆Ct) method to find the relative expression of miRNAs. The expression fold change of miR-126-3p was 1.73-fold increase in patients than controls (p= 0.010). The expression fold change of miR-423-5
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Background: The Initial (primary) stability is one of the factors that play an important role in the success of the dental implants. The purpose of this study was to evaluate the initial stability of dental implant with horizontal plate by using five analytical tests: insertion torque, removal torque, resonance frequency analysis, push-in test and pull-out test. Materials and methods: Two different lengths of dental implants (5mm and 10mm) were tested in this study; each dental implant was 4mm in diameter with a square threads shape of 1mm pitch and 0.5mm depth. The crestal area was 4.2mm diameter contained a right angle margin circumferential ring while the apical area was tapered with two self-tapping grooves. In this study, the initial s
... Show MoreRotating blades are the important parts in gas turbines. Hence, an accurate mathematical estimation (F.E.M) of the stresses and deformations characteristics was required in the design applications to avoid failure. In recent year’s there are researchers interest in the effect of temperature on solid bodies has greatly increased, The main of this study investigated the thermal and rotational effects. So, the thermal stresses due to high pressure and temperature are studies, also determine the steady state stresses and deformations of rotating blades due to mechanical effect. Many parameters such as thickness and centre of rotating are investigated in this paper. The
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Four different spectrophotometric methods are used in this study for the determination of Sulfamethoxazole and sulfanilamide drugs in pharmaceutical compounds, synthetic samples, and in their pure forms. The work comprises four chapters which are shown in the following: Chapter One: Includes a brief for Ultraviolet-Visible (UV-VIS) Absorption spectroscopy, antibacterial drugs and sulfonamides with some methods for their determination. The chapter lists two methods for optimization; univariate method and multivariate method. The later includes different types, two of these were mentioned; simplex method and design of experiment method. Chapter Two: Includes reaction of the two studied drugs with sodium nitrite and hydrochloric acid for diazo
... Show MoreIn this paper the effect of engagement length, number of teeth, amount of applied load, wave propagation time, number of cycles, and initial crack length on the principal stress distribution, velocity of crack propagation, and cyclic crack growth rate in a spline coupling subjected to cyclic torsional impact have been investigated analytically and experimentally. It was found that the stresses induced due to cyclic impact loading are higher than the stresses induced due to impact loading with high percentage depends on the number of cycles and total loading time. Also increasing the engagement length and the number of teeth reduces the principal stresses (40%) and
(25%) respectively for increasing the engagement length from (0.15 to 0