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Depression status in relation to dental caries and salivary C-Reactive Protein among 17 years old secondary school female in Baghdad City/Iraq.
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Background: Depression is a state of low mood and aversion to activity, it can affect a person's thoughts, behavior and sense of well-being. It can affect oral health and lead to an increased risk of dental caries. Dental caries is the most common oral infectious diseases that stresses the immune system and causes changes in cellular and molecular components of peripheral blood and C-Reactive Protein is one of these components, considered a key biomarker of inflammation. This study was conducted to assess the effect of depression status on dental caries among 17 years old secondary school female students in relation to salivary C-Reactive Protein. Materials and Methods: A cross sectional study was carried and the whole sample composed of 500 female students selected from First Alrasafa Directorate schools in Baghdad/ Iraq. Consent form was achieved from the ethical approval committee in College of Dentistry/University of Baghdad. All students were subjected to Children Depression Inventory questionnaire by Kovacs in 2011. Dental caries was registered according to Manji et al. 1989, Decay (1-4) Missing-Filled surface index. Subsamples were selected from high and low grade of depression to analyze C-Reactive Protein. Results: The percentage of occurrence of depression was 100%. The mean value of caries experience and severity were found to be higher among female students with high depression grade in comparison with low depression grade. The mean value for C-Reactive Protein was higher in high depression grade. There is a diversity in the results of caries experience with C-Reactive Protein. The percentage of depression occurrence was 100% which means a high degree of depression, and this could be due to the life difficulties, tension and economic issues that all lead to mental problems. The severity of dental caries increased as a result of stress and anxiety that may cause poor dental health. Psychological factors interact through complex pathophysiological and behavioral mechanisms that may cause elevated C-Reactive Protein. Conclusion: Depression has a negative impact on a person’s oral health including dental caries. Elevated C-Reactive Protein levels have been associated with psychological depression.

 

 

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Publication Date
Thu Dec 06 2018
Journal Name
Iraqi Journal Of Pharmaceutical Sciences ( P-issn 1683 - 3597 E-issn 2521 - 3512)
Formulation and Characterization of Bromocriptine Mesylate as Liquid Self-Nano Emulsifying Drug Delivery System
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Bromocriptine mesylate is a semisynthetic ergot alkaloid derivative with potent dopaminergic activity, used in the treatment of pituitary tumors, Parkinson's disease (PD), hyperprolactinaemia, neuroleptic malignant syndrome, and type 2 diabetes ,the oral bioavailability is  approximately 6%, therefore aim  its  prepare and evaluate bromocriptine mesylate  as liquid self nano emulsifying drug delivery system to enhance its solubility , dissolution and stability . Solubility study was made in different vehicles to select the best excipients for dissolving bromocriptine mesylate. Pseudo-ternary phase diagrams were constructed at 1:1, 2:1, 3:1 and 4:1 ratios of surfactant and co-surfactant, four formulations were pre

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Publication Date
Tue Feb 01 2022
Journal Name
Journal Of Structural Engineering
Experimental and Numerical Evaluation of a Welded Demountable Shear Connector through Horizontal Pushout Tests
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Extraction and mass transfer study of Cupressus sempervirens L. oil by hydro-distillation method
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Structural Performance of Slender RC Columns with Cross and Square-Shaped under Compression Load
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