Background: Dental casts come into direct contact with impression materials and other items that are contaminated by saliva and blood from a patient's mouth, leaving the casts susceptible to cross-contamination. The disinfectant solutions of the impression materials cause various adverse reactions. Therefore, disinfection of dental casts may be effective in preventing cross infection. This study was carried out to evaluate the surface hardness, dimensional accuracy, reproduction of details and surface porosity of type III, type IV and type IV extra hard dental stone after immersion in and spray by using SOLO and Sodium hypochlorite disinfectant solutions. Materials and methods: 240 Stone samples were prepared in rubber rings, A total of 60 test block were prepared for each test (surface hardness, dimensional accuracy, reproduction of details and surface porosity).the samples were divided into three groups (20 for each type of stone) type (III, IV, IV extra hard); SOLO and Sodium hypochlorite disinfectant by 2 methods (immersion and spray) were used in each test. Results: the results of dimensional accuracy, reproduction of details, surface hardness and surface porosity revealed no significant difference for all types of tested stone samples after immersion or spraying in SOLO and NaOCl except the surface hardness of type IV extra hard showed significant difference after spray with SOLO and the surface porosity of type IV extra hard showed significant difference after immersed in both SOLO and NaOCl solutions. Conclusions: Based on the results of this study immersion in and spray by using SOLO and NaOCl disinfectant solutions produced no adverse effect on dimensional accuracy, reproduction of details, surface hardness and surface porosity for type III, type IV dental stone and for type IV extra hard dental stone except for the surface hardness for type IV extra hard when sprayed with SOLO and the surface porosity when type IV extra hard stone immersed in the SOLO and NaOCl solutions.