Background: Mouth breathing can lead to introduce cold, dry unprepared air that insults the tissue of oral cavity, nasopharynx and lung, leading in turn to pathological changes in oronasal cavity, nasopharyngeal and other respiratory tissue, mouth breathing associated with nasal obstruction may lead to many health problems, in particular oral health problems such as inflammation of gingiva, oral dryness, change in oral environment that may decrease pH, salivary flow rate and increase bacteria and dental caries.Aims of the present study were to assess the oral health condition among mouth breather associated with nasal obstruction, including dental caries, oral cleanliness and gingival health condition as well as to evaluate the changes in salivary physical characteristics and salivary mutans streptococci counts, and their relation to oral variables in comparison to a control group. Materials and Methods: Thirty patients with mouth breathing associated with nasal obstruction (15 females and 15 males) were selected as a study group with an age range (18-22) years old, all subjects were examined by ENT specialist to confirm mouth breathing. A 30 gender and age matched healthy looking subjects without nasal obstruction were selected as control. The diagnosis and recording of dental caries was according to severity of dental caries lesion through the application of D1_4MFS(Manji et al., 1989). Plaque index of (Silness and Loe, 1964) was used for plaque assessment; gingival index of (Loe and Silness, 1963) was used for gingival health condition assessment. Stimulated salivary samples were collected according to (Tenovuo and Lagerlof, 1996) and the following variables were recorded: microbiological analysis included the salivary counts of mutans streptococci, salivary flow rate, salivary pH (potential of hydrogen) and then measurement of salivary viscosity by using Ostwald's viscometer. Results: Results of the present study showed that the mouth breathing group had statistically highly significant, higher plaque and gingival indices than nose breathing group (P<0.01) with a positive highly significant correlation between them in mouth breathing and nose breathing groups (r=0.56, r= 0.64, respectively).The salivary flow rate was lower among mouth breathing with highly significant difference than nose breathing (P<0.01), also salivary pH was lower among mouth breathing but with significant differencecompare to nose breathing (P<0.05); statistically a negative highly significant correlation was recorded among mouth breathing group between salivary flow rate with gingival index (r= -0.56). It has been found that salivary viscosity was not statistically significant difference between mouth breathing group and nose breathing group. The salivary viscosity was found to be inversely significantly correlated with salivary flow rate among mouth breathing group (r= -0.38). While it was positively not significantly correlated with plaque index, gingival index and counts of mutans streptococci among mouth breathing group. Data analysis of the present study showed that salivary mutans streptococci counts among mouth breathing group were higher than that among nose breathing group, difference was statistically highly significant (P<0.01). Conclusion: Mouth breathing associated with nasal obstruction may have an effect on oral health status, leading to an increase in periodontal disease and changes in dental caries.
Recently emerging pandemic SARS CoV-2 conquered our world since December 2019. Continuous efforts have been done to find out effective immunization and precise treatment stetratigies A way from therapeutic options that were tried in SARS CoV-2, an increased attention is directed to predict natural products and mainly phytochemicals as collaborative measures for this crisis. In this review, most of the mentioned compounds specially flavonoids (biacalin, hesperidin, quercetin, luteolin,, and phenolic (resveratrol, curcumin, and theaflavin) exert their effect through interfering with the action of one or more of this proteins (spike protein, papain like protease, 3 chymotrypsin like cysteine protease, and RNA dependent RNA
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Industrial characteristics calculations concentrated on the physical properties for break down voltage in sf6, cf4 gases and their mixture with different concentrations are presented in our work. Calculations are achieved by using an improved modern code simulated on windows technique. Our results give rise to a compatible agreement with the other experimental published data.
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A Strength Pareto Evolutionary Algorithm 2 (SPEA 2) approach for solving the multi-objective Environmental / Economic Power Dispatch (EEPD) problem is presented in this paper. In the past fuel cost consumption minimization was the aim (a single objective function) of economic power dispatch problem. Since the clean air act amendments have been applied to reduce SO2 and NOX emissions from power plants, the utilities change their strategies in order to reduce pollution and atmospheric emission as well, adding emission minimization as other objective function made economic power dispatch (EPD) a multi-objective problem having conflicting objectives. SPEA2 is the improved version of SPEA with better fitness assignment, density estimation, an
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Malaysia's growing population and industrialisation have increased solid waste accumulation in landfills, leading to a rise in leachate production. Leachate, a highly contaminated liquid from landfills, poses environmental risks and affects water quality. Conventional leachate treatments are costly and time-consuming due to the need for additional chemicals. Therefore, the Electrocoagulation process could be used as an alternative method. Electrocoagulation is an electrochemical method of treating water by eliminating impurities by applying an electric current. In the present study, the optimisation of contaminant removal was investigated using Response Surface Methodology. Three parameters were considered for optimisation: the curr
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For many years, the construction industry damages have been overlooked such as unreasonable consumption of resources in addition to producing a lot of construction waste but with global awareness growth towards the sustainable development issues, the sustainable construction practices have been adopted, taking into account the environment and human safety. The research aims to propose a management system for construction practices which could be adopted during constructing different types of sustainable buildings besides formulating flowcharts which clarify the required whole phases of sustainable buildings life cycle. The research includes two parts: theoretical part which generally ,handles the sustainability concepts at construction i
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This research takes up address the practical side by taking case studies for construction projects that include the various Iraqi governorates, as it includes conducting a field survey to identify the impact of parametric costs on construction projects and compare them with what was reached during the analysis and the extent of their validity and accuracy, as well as adopting the approach of personal interviews to know the reality of the state of construction projects. The results showed, after comparing field data and its measurement in construction projects for the sectors (public and private), the correlation between the expected and actual cost change was (97.8%), and this means that the data can be adopted in the re
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Amorphization of drug has been considered as an attractive approach in improving drug solubility and bioavailability. Unlike their crystalline counterparts, amorphous materials lack the long-range order of molecular packing and present the highest energy state of a solid material. Co-amorphous systems (CAM) are an innovative formulation technique by where the amorphous drugs are stabilized via powerful intermolecular interactions by means of a low molecular co-former.
This review highlights the different approaches in the preparation of co-amorphous drug delivery system, the proper selection of the co-formers. In addition, the recent advances in characterization, Industrial scale and formulation will be discussed.
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