Background: Chronic myeloid leukemia is a cancer of the white blood cells characterized by the increased and unregulated growth of predominantly myeloid cells in the bone marrow. This study aimed to determine the effect of chronic myeloid leukemia on Dental caries and Oral health status including Gingivitis, Loss of attachment, Plaque index and Calculus index as well as evaluation of salivary flow rate and salivary interleukins-6 and tumor necrosis factor-?. Material and methods: Study group consisted of (75) subjects, (25) were newly diagnosed with chronic myeloid leukemia, (25) were taking medications (Glevic), and (25) were control subjects, all aged 45-55 years old. Collection of stimulated salivary samples was performed under standard conditions, then salivary flow rate and salivary cytokines estimation was done. Clinical examination and oral health assessment were carried out under the standardized conditions of oral health surveys of World Health organization. dental plaque was scored according to the criteria of plaque Index by Silness and Loe(1964), Dental calculus was scored following the criteria of calculus component of the periodontal Index (Ramfjord, 1959), assessment of gingival health done according to the criteria of gingival Index for Loe and Silness (1963) and loss of attachment done following the criteria of WHO (1997). Caries assessment was done according to the WHO modified Decayed-Missing-Filled Index (DMF) and examination was done with a plane mouth mirror and CPI probe. Results: DMFS index were higher in the newly diagnosed group followed by the control group and then the treated group but the LSD test showed that differences were statistically not significant between each two groups, Plaque index was higher in the newly diagnosed group, and the differences were statistically significant only between the newly and the control group (p<0.05), Calculus index was higher in the newly diagnosed group and the difference was statistically significant between the newly diagnosed group and the treated group. Gingival index was higher in the control group and the difference was statistically highly significant between the new and control groups (p<0.01) and also highly significant between control group and the treated group. Loss of attachment index was higher in the control group the LSD test show that the difference was statistically significant between the control group and each one of the other two groups. In regard to saliva, salivary flow rate was higher in the control group; the difference was significant between the control and the newly diagnosed group and highly significant between control and the treated group. Interleukin-6 level was higher in the newly diagnosed group then the treated group then the control group. LSD test show that the difference was statistically significant between the new and the treated group (p<0.05) and it was highly significant between the new and the control group (p<0.01) but it was not significant between the treated and control group. TNF-? level was higher in newly diagnosed group followed by the treated group then the control group and the difference was statistically significant with the treated group and highly significant with the control group, but the difference was not significant between the treated and the control group. Conclusion: Salivary Interluekine-6 and Tumor necrosis factor- ? levels were higher in the newly diagnosed group. Saliva provides an ideal tool for the detection of pro-inflammatory markers. Salivary IL-6and TNF-? may play an important role as biomarkers for CMLand IL-6 is more predictable for the response to the treatment than TNF-?.
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Aim: The aim of this study is to determine the correlation between levels of certain seminal biochemical parameters and serum reproductive hormones, on the one hand, and sperm function tests, on the other hand, in asthenospermic patients. Patients and Methods: Sixty asthenospermic patients and twenty fertile men as a control group were included in this study. Semen samples were collected to perform seminal fluid analysis. Total protein, cholesterol, calcium, creatine kinase, and fructose were measured in the seminal plasma. Blood samples were collected for hormonal assay of serum reproductive hormones: testosterone, prolactin, luteinizing hormone, and follicle-stimulating hormone. Results: The results revealed a significant positive correla
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The time series of statistical methods mission followed in this area analysis method, Figuring certain displayed on a certain period of time and analysis we can identify the pattern and the factors affecting them and use them to predict the future of the phenomenon of values, which helps to develop a way of predicting the development of the economic development of sound
The research aims to select the best model to predict the number of infections with hepatitis Alvairose models using Box - Jenkins non-seasonal forecasting in the future.
Data were collected from the Ministry of Health / Department of Health Statistics for the period (from January 2009 until December 2013) was used
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Neuron-derived neurotrophic factor [NENF], a human plasma neurotrophic factor, also increases neurotrophic activity in conjunction with Parkinson's disease-related proteins in Neudesin. Although Neudesin (neuron-derived neurotrophic secreted protein) is a member of the membrane-associated progesterone receptor (MAPR) protein subclass, it is not evolutionary related to the other members of the same family. The expression of Neudesin is found in both brain and spinal cord from embryonic stages to adulthood, as w Neudesin levels in Parkinson's patients with osteoporosis disease and Parkinson's patients without osteoporosis disease, as well as the relationship between Neudesin levels, Anthropometric and Clinical Features (Age, Gender, BMI) and
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protein oxidation through oxidative stress, which represents the overall status of the protein in the cell/tissue. Due to their increased levels of AOPPs were reported during T2DM. The aim of this study was to assess AOPP level in T2DM subjects with foot ulcer (DFU) and explore its correlation with infection. Type 2 diabetic patients (n=108) and healthy subjects (n=25) were enrolled in this study. The T2DM group was subdivided to diabetic patients without complications (n=25) and eighty-three (83) of them have diabetic foot. They were sub- grouped into two groups according to presence Osteomyelitis and abscess, and in reliance on medical analysis of WBC count and CRP. Group of diabetic without superficial or deep ulcer and no osteomyelitis
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BACKGROUND: CRC is one of the most common cancers in the world. K-ras is proto-oncogene with GTPase activity that is lost when the gene is mutated. Analysis of K-ras mutational status is very important for CRC treatment, being the most important predictors of resistance to targeted therapy. OBJECTIVE: This study aims to determine the frequency and spectrum of K-ras mutation among Iraqi patients with sporadic CRC. PATIENTS, MATERIALS AND METHODS: This study enrolled 35 cases with sporadic CRC; their clinicopathological parameters were analyzed. The FFPE blocks were used for DNA extraction; PCR amplification of K-ras gene and hybridization of allele-specific oligoprobes were performed. The assay covers 29 mutations in the K-ras gene (codons 1
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During infection, T. gondii disseminates by the circulatory system and establishes chronic infection in several organs. Almost third of humans, immunosuppressed individuals such as HIV/AIDS patients, cancer patients, and organ transplant recipients are exposed to toxoplasmosis. Therefore, the study aimed to investigate the possibility that Toxoplasma infection could be a risk factor for COVID-19 patients and its possible correlation with C-reactive protein and ferritin. Overall 220 patients referred to the Al Furat General Hospital, Baghdad, Iraq were enrolled from 2020–2021. All serum samples were tested for T. gondii immunoglobulins (IgG and IgM) antibodies, C-reactive protein and ferritin levels. In patients with COVID-19, the results
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