Background: techniques of image analysis have been used extensively to minimize interobserver variation of immunohistochemical scoring, yet; image acquisition procedures are often demanding, expensive and laborious. This study aims to assess the validity of image analysis to predict human observer’s score with a simplified image acquisition technique. Materials and methods: formalin fixed- paraffin embedded tissue sections for ameloblastomas and basal cell carcinomas were immunohistochemically stained with monoclonal antibodies to MMP-2 and MMP-9. The extent of antibody positivity was quantified using Imagej® based application on low power photomicrographs obtained with a conventional camera. Results of the software were employed to predict human visual scoring results with stepwise multiple regression analysis. Results: the overall prediction of epithelial score depicted as r square value was 0.26 (p<0.001) which was obviously higher than that of stromal score (0.10; p<0.01). Epithelial and stromal MMP-2 score prediction was generally higher than that of MMP-9. Collectively, ameloblastomas had a more efficient score prediction compared to basal cell carcinomas. Conclusion: there is a considerable variability in the prediction capacity of the technique with respect to different antibodies, different tumors and cellular versus stromal score.
Computer analysis of simple eye model is performed in the present work by using the Zemax optical design software 2000E . The most important optical parameters of the eye were calculated such as the effective focal length (EFL) , the image spot size at the retina and found to be in a reasonable agreement with the values needed for the laser retinal treatment .The present eye model leads to an effective wavelength and we found the image spot diagram at the surface of the retina and the wavefront error which are provided at zero field angle. This gives a good evidence of the validity of the model in one hand, and can be used to determine the compatibility of any optical design intended for visual applications. By using the pulse fre
... Show MoreA promotion to a previous computer programmed technique "Photo-Micro Estimation Program" was carried out to compute the exact dimensions of cell and cell fraction in photographs of
histological sections. "Visual Basic 6" was used as a language for building of the antecedent application forms. With the aid of a slide micrometer, pixels were substituted for micrometer
(μm). The new procedure was termed "Photo-histometry program". To test the suitability of this program, eight photographs of histological sections were selected randomly to be tested. Results were contrasted with those calculated by using ocular lens (calibrated by a slide micrometer). Estimation of RBC diameter (well known, =7-8 μm) was
Background: Many thymoma classifications have been followed and have been updated by newer or alternative schemes. Many classifications were based on the morphology and histogenesis of normal thymus as the backbone, while other classifications have followed a more simplified scheme, whereby thymomas were grouped based on biological behavior. The WHO classification is currently the advocated one, which is based on “organotypical” features (i.e. histological characteristics mimicking those observed in the normal thymus) including cytoarchitecture (encapsulation and a “lobular architecture”) and the cellular composition, mostly the nuclear morphology is generally appreciated.
Objectives: Thi
... Show MoreNative speakers of English from different parts of the world have different accents,but the differences of accents are mainly the result of differences in the sound of vowels and consonants . The actual use of all these sounds in combination leads the speaker to produce a number of segments which only appear on the production level and realized on the perceptual one . RP pronunciation represents the teachable variety in all Iraqi universities because it is the most acceptable and understandable accent all over the world and not only in South East London ..The structure of the English syllable in RP pronunciation is influenced by the appearance of certain allophones especially aspiration and glottalization which ch
... Show MoreThis paper introduced an algorithm for lossless image compression to compress natural and medical images. It is based on utilizing various casual fixed predictors of one or two dimension to get rid of the correlation or spatial redundancy embedded between image pixel values then a recursive polynomial model of a linear base is used.
The experimental results of the proposed compression method are promising in terms of preserving the details and the quality of the reconstructed images as well improving the compression ratio as compared with the extracted results of a traditional linear predicting coding system.
This paper presents the matrix completion problem for image denoising. Three problems based on matrix norm are performing: Spectral norm minimization problem (SNP), Nuclear norm minimization problem (NNP), and Weighted nuclear norm minimization problem (WNNP). In general, images representing by a matrix this matrix contains the information of the image, some information is irrelevant or unfavorable, so to overcome this unwanted information in the image matrix, information completion is used to comperes the matrix and remove this unwanted information. The unwanted information is handled by defining {0,1}-operator under some threshold. Applying this operator on a given ma
... Show MoreSolid dispersion (SD) is one of the most widely used methods to resolve issues accompanied by poorly soluble drugs. The present study was carried out to enhance the solubility and dissolution rate of Aceclofenac (ACE), a BCS class II drug with pH-dependent solubility, by the SD method. Effervescent assisted fusion technique (EFSD) using different hydrophilic carriers (mannitol, urea, Soluplus®, poloxamer 188, and poloxamer 407) in the presence of an effervescent base (sodium bicarbonate and citric acid) in different drug: carrier: effervescent base ratio and the conventional fusion technique (FSD) were used to prepare ACE SD. Solubility, dissolution rate, Fourier transformation infrared spectroscopy (FTIR), PowderX-ray diffraction
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